Extrastriatal and striatal D₂ dopamine receptor blockade with haloperidol or new antipsychotic drugs in patients with schizophrenia

Positron Emission Tomographic Analysis of Central D1 and D2 Dopamine Receptor Occupancy in Patients Treated With Classical Neuroleptics and Clozapine

1992 • 1,420 citations

Verapamil

1978 • 829 citations

Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients

1993 • 529 citations

Neurochemical characteristics of amisulpride, an atypical dopamine D2/D3 receptor antagonist with both presynaptic and limbic selectivity.

1997 • 358 citations

Controlled, dose-response study of sertindole and haloperidol in the treatment of schizophrenia. Sertindole Study Group

1997 • 311 citations

Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography.

1985 • 304 citations

The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophrenia

1999 • 282 citations

Clozapine

1990 • 272 citations

Suggested Minimal Effective Dose of Risperidone Based on PET-Measured D₂ and 5-HT_2A Receptor Occupancy in Schizophrenic Patients

1999 • 243 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex.

1994 • 175 citations

Identification of extrastriatal dopamine D2 receptors in post mortem human brain with [125I]epidepride

1993 • 157 citations

On the significance of regional dopamine metabolism in the rat brain for the classification of centrally acting drugs

1977 • 117 citations

Binding interactions of lysergic acid diethylamide and related agents with dopamine receptors in the brain.

1976 • 109 citations

Brain Dopamine and Serotonin Receptor Sites Revealed by Digital Subtraction Autoradiography

1985 • 106 citations

Amisulpride

1996 • 105 citations

Fast Nonsupervised 3D Registration of PET and MR Images of the Brain

1994 • 96 citations

Effects of typical and atypical neuroleptics on Fos protein expression in the rat forebrain

1994 • 94 citations

In Vivo Extrastriatal and Striatal D2 Dopamine Receptor Blockade by Amisulpride in Schizophrenia

2001 • 93 citations

Striatal and temporal cortical D2/D3 receptor occupancy by olanzapine and sertindole in vivo: a [ 123 I]epidepride single photon emission tomography (SPET) study

2000 • 88 citations

Striatal and extra-striatal D₂/D₃ dopamine receptor occupancy by quetiapine in vivo

2000 • 83 citations

Quantitation of Extrastriatal D2 Receptors Using a Very High-Affinity Ligand (FLB 457) and the Multi-Injection Approach

1999 • 71 citations

Comparison of the In-vitro Receptor Selectivity of Substituted Benzamide Drugs for Brain Neurotransmitter Receptors

1988 • 58 citations

Risperidone and olanzapine

1998 • 54 citations

A common action of clozapine, haloperidol, and remoxipride on D1- and D2-dopaminergic receptors in the primate cerebral cortex

1994 • 54 citations

In vivo occupancy of striatal and temporal cortical D₂/D₃ dopamine receptors by typical antipsychotic drugs

1999 • 49 citations

State of the Art of Drug Treatment of Schizophrenia and the Future Position of the Novel/Atypical Antipsychotics

2000 • 48 citations

Effects of chronic administration of neuroleptic and anticholinergic agents on densities of D2 dopamine and muscarinic cholinergic receptors in rat striatum.

1988 • 36 citations

Preparation of [76Br]FLB 457 and [76Br]FLB 463 for examination of striatal and extrastriatal dopamine D-2 receptors with PET

1996 • 31 citations

Central D₂receptor blockade and antipsychotic effects of neuroleptics. Preliminary study with positron emission tomography

1990 • 21 citations

A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Efficacy in the Management of Schizophrenia

1996 • 17 citations