Amiodarone-induced enhancement of doxorubicin and 4'-deoxydoxorubicin cytotoxicity to rat colon cancer cells in vitro and in vivo.

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil.

1981 • 1,463 citations

Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.

1982 • 667 citations

Amiodarone

1981 • 577 citations

Reversal of Adriamycin Resistance by Verapamil in Human Ovarian Cancer

1984 • 398 citations

Potentiation of vincristine and Adriamycin effects in human hemopoietic tumor cell lines by calcium antagonists and calmodulin inhibitors.

1983 • 250 citations

Effects of quinidine and related compounds on cytotoxicity and cellular accumulation of vincristine and adriamycin in drug-resistant tumor cells.

1984 • 231 citations

Chemotherapy of Gastrointestinal Cancer

1978 • 229 citations

Steady-State Serum Amiodarone Concentrations: Relationships with Antiarrhythmic Efficacy and Toxicity

1984 • 203 citations

Pharmacokinetics of amiodarone after intravenous and oral administration

1981 • 198 citations

Evaluation of single agents and combinations of chemotherapeutic agents in mouse colon carcinomas

1977 • 184 citations

Reversal of acquired resistance to doxorubicin in P388 murine leukemia cells by tamoxifen and other triparanol analogues.

1984 • 182 citations

Cardiac actions in the dog of a new antagonist of adrenergic excitation which does not produce competitive blockade of adrenoceptors

1970 • 180 citations

Selection by trypsin of two sublines of rat colon cancer cells forming progressive or regressive tumors

1983 • 176 citations

Verapamil Restoration of Daunorubicin Responsiveness in Daunorubicin-resistant Ehrlich Ascites Carcinoma

1982 • 157 citations

Differential killing efficacy of twenty antitumor drugs on proliferating and nonproliferating human tumor cells.

1981 • 149 citations

Anthracycline resistance in P388 murine leukemia and its circumvention by calcium antagonists.

1985 • 149 citations

Carrier-mediated transport of daunorubicin, adriamycin, and rubidazone in ehrlich ascites tumour cells

1978 • 121 citations

Interaction between two cellular subpopulations of a rat colonic carcinoma when inoculated to the syngeneic host

1985 • 119 citations

Cellular pharmacodynamics of several anthracycline antibiotics

1976 • 109 citations

High calcium content of pleiotropic drug-resistant P388 and K562 leukemia and Chinese hamster ovary cells.

1984 • 65 citations

Flow cytometric studies on modulation of cellular adriamycin retention by phenothiazines.

1985 • 63 citations

Differential effect of the calmodulin inhibitor trifluoperazine on cellular accumulation, retention, and cytotoxicity of anthracyclines in doxorubicin (adriamycin)-resistant P388 mouse leukemia cells.

1984 • 63 citations

Restored in vitro sensitivity of adriamycin- and vincristine-resistant P388 leukemia with reserpine

1981 • 58 citations

Cytofluorescence localization of adriamycin in resistant colon cancer cells

1984 • 44 citations

A carcinofetal antigen located on the membrane of cells from rat intestinal carcinoma in culture.

1975 • 37 citations

Effect of cell density on intracellular adriamycin concentration and cytotoxicity in exponential and plateau phase EMT6 cells

1984 • 36 citations

Chemotherapy of human colorectal tumor xenografts in athymic mice with clinically active drugs: 5‐fluorouracile and 1‐3‐bis‐(‐2‐chloroethyl)‐1‐nitrosourea (bcnu). Comparison with doxorubicin derivatives: 4′deoxydoxorubicin and 4′‐0‐methyldoxorubicin

1981 • 29 citations

Enhancement of doxorubicin and vinblastine sensitivity in anthracycline-resistant P388 cells.

1983 • 27 citations

Evidence of altered influx of adriamycin into anthracycline-resistant cells.

1981 • 25 citations

Comparison of the activity of doxorubicin analogues using colony-forming assays and human xenografts

1982 • 23 citations

The antitumoral activity of 4′-deoxydoxorubicin compared to doxorubicin and 5-fluorouracil on methylazoxymethanol acetate-induced colon tumors in CF1 mice

1984 • 10 citations