UBPY: a growth-regulated human ubiquitin isopeptidase

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

Cell Cycle Control and Cancer

1994 • 2,575 citations

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

1995 • 1,848 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control

1993 • 1,096 citations

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

1994 • 930 citations

Ubiquitin, proteasomes, and the regulation of intracellular protein degradation

1995 • 862 citations

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway.

1997 • 747 citations

Regulation of ubiquitin‐dependent processes by deubiquitinating enzymes

1997 • 576 citations

Prediction of the Coding Sequences of Unidentified Human Genes. II. The Coding Sequences of 40 New Genes (KIAA0041-KIAA0080) Deduced by Analysis of cDNA Clones from Human Cell Line KG-1

1994 • 500 citations

A novel ubiquitin-specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein

1997 • 484 citations

A Link Between Cyclin A Expression and Adhesion-Dependent Cell Cycle Progression

1993 • 399 citations

The yeast DOA4 gene encodes a deubiquitinating enzyme related to a product of the human tre-2 oncogene

1993 • 379 citations

Functions of the Proteasome: the Lysis at the End of the Tunnel

1995 • 302 citations

Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts.

1994 • 296 citations

Metabolism of the polyubiquitin degradation signal: structure, mechanism, and role of isopeptidase T

1995 • 292 citations

Control of Cell Fate by a Deubiquitinating Enzyme Encoded by the fat facets Gene

1995 • 262 citations

Ubiquitin-specific proteases of Saccharomyces cerevisiae. Cloning of UBP2 and UBP3, and functional analysis of the UBP gene family

1992 • 250 citations

A Deubiquitinating Enzyme Interacts with SIR4 and Regulates Silencing in S. cerevisiae

1996 • 228 citations

Cell cycle regulation by the ubiquitin pathway

1997 • 214 citations

Epitope-tagged ubiquitin. A new probe for analyzing ubiquitin function.

1991 • 212 citations

Degradation of E2F by the ubiquitin-proteasome pathway: regulation by retinoblastoma family proteins and adenovirus transforming proteins.

1996 • 207 citations

Induction of S-Phase Entry by E2F Transcription Factors Depends on Their Nuclear Localization

1997 • 195 citations

The fat facets gene is required for Drosophila eye and embryo development

1992 • 187 citations

Physical Interaction between Specific E2 and Hect E3 Enzymes Determines Functional Cooperativity

1997 • 150 citations

A novel transcriptional unit of the tre oncogene widely expressed in human cancer cells.

1992 • 117 citations

The ubiquitin-mediated proteolytic pathway as a therapeutic area

1997 • 113 citations

DUB-2 Is a Member of a Novel Family of Cytokine-inducible Deubiquitinating Enzymes

1997 • 111 citations

Elevated expression of Unph, a proto-oncogene at 3p21.3, in human lung tumors

1995 • 92 citations

The Unp proto-oncogene encodes a nuclear protein.

1994 • 66 citations

Unp, a mouse gene related to the tre oncogene.

1993 • 58 citations

The MurineDUB-1Gene Is Specifically Induced by the βc Subunit of the Interleukin-3 Receptor

1996 • 54 citations

The Dose of a Putative Ubiquitin-Specific Protease Affects Position-Effect Variegation in Drosophila melanogaster

1996 • 51 citations

JAK2 Is Required for Induction of the Murine DUB-1 Gene

1997 • 49 citations

A human de‐ubiquitinating enzyme with both isopeptidase and peptidase activities in vitro

1995 • 47 citations

A ubiquitin C-terminal hydrolase gene on the proximal short arm of the X chromosome: implications for X-linked retinal disorders

1996 • 34 citations

A rearranged transforming gene, tre, is made up of human sequences derived from chromosome regions 5q, 17q and 18q.

1988 • 34 citations

Expression and accurate processing of yeast penta-ubiquitin in Escherichia coli.

1987 • 27 citations

Molecular cloning of a novel oncogene generated by DNA recombination during transfection.

1988 • 26 citations

cDNA cloning of a human 100 kDa de‐ubiquitinating enzyme: the 100 kDa human de‐ubiquitinase belongs to the ubiquitin C‐terminal hydrolase family 2 (UCH2)

1995 • 22 citations

Protein degradation: De-ubiquitinate to decide your fate

1996 • 21 citations

Targeting Ubiquitin-Mediated Degradation for Proliferation Inhibitors

1996 • 13 citations

Cell cycle control and cancer

1996 • 5 citations