Distinct pathways regulate transforming growth factor β1‐stimulated proto‐oncogene and extracellular matrix gene expression

Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

1986 • 2,878 citations

Transforming growth factor beta

2011 • 1,990 citations

pl Bl5: A cDNA Clone of the Rat mRNA Encoding Cyclophilin

1988 • 1,039 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

Growth Inhibitor from BSC-1 Cells Closely Related to Platelet Type β Transforming Growth Factor

1984 • 779 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

G protein involvement in receptor-effector coupling.

1988 • 618 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

1986 • 541 citations

Polypeptide Transforming Growth Factors Isolated from Bovine Sources and Used for Wound Healing in Vivo

1983 • 451 citations

Reversible Inhibition of Mammary Gland Growth by Transforming Growth Factor-β

1987 • 408 citations

Transforming growth factor-β inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor

1989 • 325 citations

Antiphosphotyrosine Recovery of Phospholipase C Activity After EGF Treatment of A-431 Cells

1988 • 324 citations

Phosphoinositides and receptor mechanisms

1987 • 320 citations

Two growth factor signalling pathways in fibroblasts distinguished by pertussis toxin

1987 • 254 citations

Thrombin stimulates c-sis gene expression in microvascular endothelial cells.

1986 • 235 citations

The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane protein

1983 • 215 citations

Type beta transforming growth factor/growth inhibitor stimulates entry of monolayer cultures of AKR-2B cells into S phase after a prolonged prereplicative interval.

1985 • 191 citations

The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.

1987 • 140 citations

Ras p21 proteins with high or low GTPase activity can efficiently transform NIH3T3 cells

1986 • 118 citations

Transforming growth factor type β regulation of actin mRNA

1986 • 116 citations

TGF‐β inhibits growth factor‐induced DNA synthesis in hamster fibroblasts without affecting the early mitogenic events

1988 • 99 citations

Regulation of platelet-derived growth factor gene expression by transforming growth factor beta and phorbol ester in human leukemia cell lines.

1987 • 86 citations

Possible involvement of a GTP-binding protein, the substrate of islet-activating protein, in receptor-mediated signaling responsible for cell proliferation.

1987 • 85 citations

G-protein-mediated epidermal growth factor signal transduction in a human breast cancer cell line. Evidence for two intracellular pathways distinguishable by pertussis toxin.

1988 • 71 citations

Transforming growth factor β1 treatment of AKR-2B cells is coupled through a pertussis-toxin-sensitive G-protein(s)

1989 • 57 citations

Identification of a new GTP-binding protein. A Mr = 43,000 substrate for pertussis toxin.

1987 • 57 citations

Coupling of TGF-β-induced mitogenesis to G-protein activation in AKR-2B cells

1988 • 52 citations

Transforming growth factor beta modulates epidermal growth factor-induced phosphoinositide metabolism and intracellular calcium levels.

1988 • 49 citations

Modulation of transforming growth factor type beta action by activated ras and c-myc.

1987 • 40 citations

Distinct pathways mediate transcriptional regulation of platelet-derived growth factor B/c-sis expression.

1988 • 34 citations

Cell-Type-Specific Synthesis of Murine Immunoglobulin μ RNA from an Adenovirus Vector

1986 • 28 citations

G proteins flex their muscles

1988 • 25 citations

Transforming Growth Factors

1987 • 14 citations

Cell-type-specific synthesis of murine immunoglobulin mu RNA from an adenovirus vector.

1986 • 12 citations