Control of gene expression and assembly of chromosomal subdomains by chromatin regulators with antagonistic functions

Translating the Histone Code

2001 • 9,488 citations

Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

2017 • 5,610 citations

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

2004 • 3,675 citations

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

2001 • 2,768 citations

Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

2001 • 2,746 citations

Regulation of chromatin structure by site-specific histone H3 methyltransferases

2000 • 2,709 citations

Active genes are tri-methylated at K4 of histone H3

2002 • 2,064 citations

X-inactivation profile reveals extensive variability in X-linked gene expression in females

2005 • 1,968 citations

Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability

2001 • 1,672 citations

Histone and chromatin cross-talk

2003 • 1,187 citations

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

2002 • 1,176 citations

Partitioning and Plasticity of Repressive Histone Methylation States in Mammalian Chromatin

2003 • 1,109 citations

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

2004 • 1,073 citations

Heterochromatin and Epigenetic Control of Gene Expression

2003 • 1,039 citations

Human PAD4 Regulates Histone Arginine Methylation Levels via Demethylimination

2004 • 955 citations

Histone Deimination Antagonizes Arginine Methylation

2004 • 796 citations

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

2004 • 788 citations

Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains

2003 • 776 citations

Histone H3 lysine 4 methylation patterns in higher eukaryotic genes

2003 • 772 citations

The Establishment, Inheritance, and Function of Silenced Chromatin inSaccharomyces cerevisiae

2003 • 717 citations

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing

2002 • 691 citations

Establishment of Histone H3 Methylation on the Inactive X Chromosome Requires Transient Recruitment of Eed-Enx1 Polycomb Group Complexes

2003 • 646 citations

Binary switches and modification cassettes in histone biology and beyond

2003 • 628 citations

Conserved Histone Variant H2A.Z Protects Euchromatin from the Ectopic Spread of Silent Heterochromatin

2003 • 619 citations

Maintenance of Stable Heterochromatin Domains by Dynamic HP1 Binding

2003 • 608 citations

Correlation Between Histone Lysine Methylation and Developmental Changes at the Chicken β-Globin Locus

2001 • 582 citations

PR-Set7 Is a Nucleosome-Specific Methyltransferase that Modifies Lysine 20 of Histone H4 and Is Associated with Silent Chromatin

2002 • 571 citations

The role of RNA interference in heterochromatic silencing

2004 • 563 citations

Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin

2004 • 554 citations

Conserved Organization of Centromeric Chromatin in Flies and Humans

2002 • 526 citations

Histone Methylation

2002 • 525 citations

Sequencing of a rice centromere uncovers active genes

2004 • 519 citations

Purification and Functional Characterization of a Histone H3-Lysine 4-Specific Methyltransferase

2001 • 511 citations

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin

2001 • 495 citations

Types of visible variations induced by X-rays inDrosophila

1930 • 462 citations

Sir2p and Sas2p opposingly regulate acetylation of yeast histone H4 lysine16 and spreading of heterochromatin

2002 • 428 citations

Transient Inhibition of Histone Deacetylation Alters the Structural and Functional Imprint at Fission Yeast Centromeres

1997 • 367 citations

Position effect variegation at fission yeast centromeres

1994 • 332 citations

Purification and Functional Characterization of SET8, a Nucleosomal Histone H4-Lysine 20-Specific Methyltransferase

2002 • 321 citations

Methylation at arginine 17 of histone H3 is linked to gene activation

2002 • 319 citations

H2A.Z Alters the Nucleosome Surface to Promote HP1α-Mediated Chromatin Fiber Folding

2004 • 300 citations

Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A

2001 • 289 citations

Methylation of Histone H3 K4 Mediates Association of the Isw1p ATPase with Chromatin

2003 • 279 citations

The Heterochromatin Protein 1 Prevents Telomere Fusions in Drosophila

1998 • 274 citations

Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila

2004 • 271 citations

Position-effect variegation and the new biology of heterochromatin

1994 • 244 citations

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes

2002 • 234 citations

Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development

2003 • 230 citations

Multiple spatially distinct types of facultative heterochromatin on the human inactive X chromosome

2004 • 228 citations

The JIL-1 Tandem Kinase Mediates Histone H3 Phosphorylation and Is Required for Maintenance of Chromatin Structure in Drosophila

2001 • 215 citations

Regulation of heterochromatin by histone methylation and small RNAs

2004 • 207 citations

The role of histone H2Av variant replacement and histone H4 acetylation in the establishment of Drosophila heterochromatin

2005 • 166 citations

Variegation in Drosophila and the Inert Chromosome Regions

1936 • 164 citations

A solid foundation: functional specialization of centromeric chromatin

2001 • 161 citations

Proteolytic processing of histone H3 in chromatin: a physiologically regulated event in tetrahymena micronuclei

1980 • 143 citations

SU(VAR)3-7, a Drosophila heterochromatin-associated protein and companion of HP1 in the genomic silencing of position-effect variegation

1997 • 141 citations

The Activation of a Neocentromere in Drosophila Requires Proximity to an Endogenous Centromere

2001 • 128 citations

Methylation of H3 Lysine 4 at Euchromatin Promotes Sir3p Association with Heterochromatin

2004 • 117 citations

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere

2004 • 84 citations

Histone H4 Hyperacetylation Precludes Histone H4 Lysine 20 Trimethylation

2004 • 68 citations

Promoter-restricted H3 Lys 4 di-methylation is an epigenetic mark for monoallelic expression

2003 • 41 citations