Estrogens, apoptosis and cells of neural origin.

Cloning of a novel receptor expressed in rat prostate and ovary.

1996 • 4,782 citations

MOLECULAR MECHANISMS OF ACTION OF STEROID/THYROID RECEPTOR SUPERFAMILY MEMBERS

1994 • 2,875 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

Comparative distribution of estrogen receptor-? and -? mRNA in the rat central nervous system

1997 • 2,244 citations

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease

1996 • 1,640 citations

Cell Membrane and Nuclear Estrogen Receptors (ERs) Originate from a Single Transcript: Studies of ERα and ERβ Expressed in Chinese Hamster Ovary Cells

1999 • 1,046 citations

A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease

1997 • 965 citations

Estrogen Therapy in Postmenopausal Women

1998 • 927 citations

Cloning, Chromosomal Localization, and Functional Analysis of the Murine Estrogen Receptor β

1997 • 862 citations

Estrogens Attenuate and Corticosterone Exacerbates Excitotoxicity, Oxidative Injury, and Amyloid β‐Peptide Toxicity in Hippocampal Neurons

1996 • 833 citations

Neuroprotection against Oxidative Stress by Estrogens: Structure-Activity Relationship

1997 • 769 citations

17-β Estradiol Protects Neurons from Oxidative Stress-Induced Cell Death in Vitro

1995 • 612 citations

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

1991 • 577 citations

Membrane estrogen receptors identified by multiple antibody labeling and impeded‐ligand binding

1995 • 532 citations

Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor.

1992 • 486 citations

Estrogen-Induced Activation of Mitogen-Activated Protein Kinase in Cerebral Cortical Explants: Convergence of Estrogen and Neurotrophin Signaling Pathways

1999 • 474 citations

Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins

1994 • 467 citations

Estradiol Modulates bcl-2 in Cerebral Ischemia: A Potential Role for Estrogen Receptors

1999 • 453 citations

Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I.

1993 • 442 citations

Estrogen Modulates Neuronal Bcl‐x_l Expression and β‐Amyloid‐Induced Apoptosis

1999 • 390 citations

A potential role for apoptosis in neurodegeneration and Alzheimer's disease

1995 • 382 citations

Differential Regulation of NMDAR1 mRNA and Protein by Estradiol in the Rat Hippocampus

1996 • 376 citations

The Estrogen Receptor Enhances AP-1 Activity by Two Distinct Mechanisms with Different Requirements for Receptor Transactivation Functions

1999 • 369 citations

17β-Estradiol Potentiates Kainate-Induced Currents via Activation of the cAMP Cascade

1996 • 347 citations

Estrogen-induced activation of mitogen-activated protein kinase requires mobilization of intracellular calcium

1999 • 336 citations

The distribution of estrogen receptor-β mRNA in the rat hypothalamus

1996 • 288 citations

Mechanism of the Rapid Effect of 17β-Estradiol on Medial Amygdala Neurons

1986 • 266 citations

17α-Estradiol Exerts Neuroprotective Effects on SK-N-SH Cells

1997 • 259 citations

Estradiol upregulates Bcl-2 expression in adult brain neurons

1998 • 253 citations

Rapid Action of 17β-Estradiol on Kainate-Induced Currents in Hippocampal Neurons Lacking Intracellular Estrogen Receptors*

1999 • 233 citations

Demonstration of steroid hormone receptors and steroid action in primary cultures of rat glial cells

1992 • 188 citations

Phosphorylation of the human estrogen receptor on tyrosine 537 in vivo and by src family tyrosine kinases in vitro.

1995 • 183 citations

The role of estrogen in the treatment of Alzheimer's disease

1997 • 176 citations

Estrogen Receptor Is Expressed in Different Types of Glial Cells in Culture

1994 • 162 citations

The Alzheimer's disease assessment scale

1997 • 157 citations

Estrogen and microglia: A regulatory system that affects the brain

1999 • 151 citations

Estradiol 17β increases the number of muscarinic receptors in hypothalamic nuclei

1980 • 146 citations

Estrogens attenuate neuronal injury due to hemoglobin, chemical hypoxia, and excitatory amino acids in murine cortical cultures

1997 • 138 citations

Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3.

1994 • 136 citations

Electrophysiological evidence for a rapid membrane action of the gonadal steroid, 17β-estradiol, on CA1 pyramidal neurons of the rat hippocampus

1991 • 120 citations

Estrogen receptor-dependent regulation of sensory neuron survival in developing dorsal root ganglion

1999 • 112 citations

Comment

1995 • 105 citations

Estrogen Receptor β: Re-evaluation of Estrogen and Antiestrogen Signaling

1998 • 105 citations

Activated estrogen receptor mediates growth arrest and differentiation of a neuroblastoma cell line.

1993 • 85 citations

Estrogen Induction of Cytochrome c Oxidase Subunit III in Rat Hippocampus

1992 • 84 citations

Cross-coupling between insulin and estrogen receptor in human neuroblastoma cells.

1996 • 84 citations

Estrogen- and tamoxifen-induced rearrangement of cytoskeletal and adhesion structures in breast cancer MCF-7 cells.

1986 • 83 citations

Estrogen‐Induced Up‐Regulation of γ‐Aminobutyric Acid Receptors in the CNS of Rodents

1986 • 81 citations

Effects of estradiol and progesterone on voltage-gated calcium and potassium conductances in rat CA1 hippocampal neurons

1995 • 81 citations

Estrogen Induces Accumulation of the Mitochondrial Ribonucleic Acid for Subunit II of Cytochrome Oxidase in Pituitary Tumor Cells

1988 • 79 citations

Estradiol Induces Differential Neuronal Phenotypes by Activating Estrogen Receptor α or β¹

2000 • 72 citations

Divergent Pathways Regulate Ligand-Independent Activation of ERα in SK-N-BE Neuroblastoma and COS-1 Renal Carcinoma Cells

1998 • 71 citations

Steroid Hormone Influences on Spatial Memory

1994 • 67 citations

Identification of Estrogen-Responsive Genes in Neuroblastoma SK-ER3 Cells

1997 • 65 citations

Sex steroids modulate motor-correlated increases in cerebellar discharge

1989 • 60 citations

Estrogen-induced efflux of endogenous catecholamines from the hypothalamus in vitro

1979 • 60 citations

Effect of estrogen on the expression of mRNAs of different actin isoforms in immature rat uterus. Cloning of alpha-smooth muscle actin message.

1987 • 52 citations

Distribution and Localization of Estrogen‐Sensitive Dopamine Receptors in the Rat Brain

1982 • 48 citations

Oestrogen Prevention of Neural Cell Death Correlates with Decreased Expression of mRNA for the Pro‐Apoptotic Protein Nip‐2

2000 • 43 citations

SK-ER3 Neuroblastoma Cells as a Model for the Study of Estrogen Influence on Neural Cells

1997 • 37 citations

Dopaminergic Phenotype Induced by Oestrogens in a Human Neuroblastoma Cell Line

1997 • 34 citations

Activation of kappa B-specific proteins by estradiol.

1992 • 33 citations

Short-term effect of estrogen on release of prolactin by pituitary cells in culture

1981 • 31 citations

Diethylstilbestrol regulates the number of α- and β-adrenergic binding sites in incubated hypothalamus and amygdala

1982 • 31 citations

Effects of Estrogen and Epidermal Growth Factor on Prolactin and Pit-1 mRNA in GH3 Cells

1993 • 30 citations

Estrogen as a Psychotherapeutic Agent

1998 • 23 citations

Increase of serotonin receptors in rat uterus induced by estradiol.

1983 • 20 citations

Decrease of the Number of Opioid Receptors and of the Responsiveness to Morphineduring Neuronal Differentiation Induced by 17β-Estradiol in Estrogen Receptor-Transfected Neuroblastoma Cells (SK-ER3)

1999 • 15 citations