Brain mechanisms in cytokine-induced anorexia

Tumor necrosis factor and interleukin-1β: suppression of food intake by direct action in the central nervous system

1988 • 414 citations

Immunoregulators in the nervous system

1991 • 380 citations

Anorexia during acute and chronic disease

1996 • 248 citations

Anorexia induced by cytokine interactions at pathophysiological concentrations

1996 • 186 citations

Anorexia induced by chronic central administration of cytokines at estimated pathophysiological concentrations

1996 • 152 citations

Interleukin-1β inhibits Ca2+ channel currents in hippocampal neurons through protein kinase C

1994 • 136 citations

Mode of action of OB protein (leptin) on feeding

1998 • 118 citations

Interleukin-1β depresses calcium currents in CA1 hippocampal neurons at pathophysiological concentrations

1992 • 116 citations

Neuropeptide Y blocks and reverses interleukin-1β-induced anorexia in rats

1996 • 103 citations

Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells

1998 • 101 citations

Cytokines and anorexia: a brief overview.

1998 • 97 citations

Meal patterns in response to the intracerebroventricular administration of interleukin-1β in rats

1994 • 96 citations

Intracerebroventricular administration of a specific IL-1 receptor antagonist blocks food and water intake suppression induced by interleukin-1β

1992 • 94 citations

Central Nervous System IL-1β System and Neuropeptide Y mRNAs During IL-1β-induced Anorexia in Rats

1997 • 91 citations

Immunomodulators and feeding regulation: A humoral link between the immune and nervous systems

1989 • 86 citations

Lipopolysaccharide (LPS)- and muramyl dipeptide (MDP)-induced anorexia during refeeding following acute fasting: characterization of brain cytokine and neuropeptide systems mRNAs

1998 • 77 citations

Chemokines/intercrines and central regulation of feeding

1994 • 75 citations

Interleukin-1β System (Ligand, Receptor Type I, Receptor Accessory Protein and Receptor Antagonist), TNF-α, TGF-β1 and Neuropeptide Y mRNAs in Specific Brain Regions During Bacterial LPS-Induced Anorexia

1998 • 73 citations

Centrally administered bacterial lipopolysaccharide depresses feeding in rats

1993 • 65 citations

Anorexia induced by activators of the signal transducer gp 130

1996 • 63 citations

Interferons and central regulation of feeding

1992 • 62 citations

Cytokines and feeding suppression: an integrative view from neurologic to molecular levels.

1995 • 60 citations

Interleukin-1? (IL-1?)-induced modulation of the hypothalamic IL-1? system, tumor necrosis factor-?, and transforming growth factor-?1 mRNAs in obese (fa/fa) and lean (Fa/Fa) Zucker rats: Implications to IL-1? feedback systems and cytokine-cytokine interactions

1997 • 55 citations

Gram-negative and gram-positive bacterial products induce differential cytokine profiles in the brain: analysis using an integrative molecular-behavioral in vivo model.

1998 • 51 citations

Regulation of Hunger and Satiety in Man

1991 • 44 citations

Interleukin-2 modulates calcium currents in dissociated hippocampal CA1 neurons

1993 • 41 citations

Interleukin-8 modulates feeding by direct action in the central nervous system

1993 • 41 citations

Dexamethasone inhibits food intake suppression induced by low doses of interleukin-1 β administered intracerebroventricularly

1991 • 40 citations

Differential Responsiveness of Obese (fa/fa) and Lean (Fa/Fa) Zucker Rats to Cytokine‐Induced Anorexia

1997 • 39 citations

In Vivo Regulation of the IL-1β System (Ligand, Receptors I and II, Receptor Accessory Protein, and Receptor Antagonist) and TNF-α mRNAs in Specific Brain Regions

1996 • 38 citations

Interleukin-1 (IL-1) Receptor Type I Mediates Anorexia but not Adipsia Induced by Centrally Administered IL-1β

1997 • 37 citations

HIV-1 gp120 Modulates Hypothalamic Cytokine mRNAsin Vivo:Implications to Cytokine Feedback Systems

1997 • 34 citations

HIV-1 Envelope Glycoprotein 120 Regulates Brain IL-1 β System and TNF- α mRNAs In Vivo

1997 • 33 citations

Cytokines and Feeding

1998 • 33 citations

Residual Ca2+ channel current modulation by megestrol acetate via a G‐protein alpha s‐subunit in rat hypothalamic neurones.

1995 • 28 citations

Modulation of TNF-α mRNA production in rat C6 glioma cells by TNF-α, IL-1β, IL-6, and IFN-α: In vitro analysis of cytokine-cytokine interactions

1998 • 27 citations

Cytokine-induced fever in obese (fa/fa) and lean (Fa/Fa) Zucker rats

1998 • 21 citations

Interleukin-1α (IL-1α), IL-1β, IL-1 receptor type I, IL-1 receptor antagonist, and TGF-β1 mRNAs in pediatric astrocytomas, ependymomas, and primitive neuroectodermal tumors

1998 • 20 citations

Regulation of brain interleukin-1β (IL-1β) system mRNAs in response to pathophysiological concentrations of IL-1β in the cerebrospinal fluid

1996 • 19 citations

Antisense oligodeoxynucleotides to G-protein α-subunit subclasses identify a transductional requirement for the modulation of normal feeding dependent on GαOA subunit

1995 • 19 citations

In vivo IL-1β-induced modulation of G-protein αO subunit subclass in the hypothalamic ventromedial nucleus: implications to IL-1β-associated anorexia

1998 • 18 citations

Molecular regulation of the brain interleukin-1β system in obese (fa/fa) and lean (Fa/Fa) Zucker rats

1996 • 15 citations

Cytokines and Ingestive Behavior: Methods and Overview

1993 • 14 citations

Strategies for potential manipulation of anorexia during acute and chronic disease.

1995 • 13 citations

Hypothalamus and the Control of Feeding: Fifteen Decades of Direct Association

1998 • 13 citations

Modulation of feeding by beta 2-microglobulin, a marker of immune activation

1995 • 12 citations

Cytokine Action in the Nervous System at Pathophysiological Versus Pharmacological Concentrations

1996 • 9 citations

An approach to study molecular mechanisms involved in cytokine-induced anorexia

1996 • 8 citations

Polyunsaturated Fatty Acids and Disease-associated and Cytokine-induced Neurological Manifestations

1998 • 1 citations