Elevated Prenatal Homocysteine Levels as a Risk Factor for Schizophrenia

Statistical methods in cancer research. Volume I - The analysis of case-control studies.

1980 • 4,991 citations

Diagnostic Interview for Genetic Studies

1994 • 2,004 citations

The neuropathology of schizophrenia

1999 • 1,664 citations

Child developmental risk factors for adult schizophrenia in the British 1946 birth cohort

1994 • 1,326 citations

Obstetric Complications and Schizophrenia: Historical and Meta-Analytic Review

2002 • 1,103 citations

Serologic Evidence of Prenatal Influenza in the Etiology of Schizophrenia

2004 • 1,017 citations

MTHFR 677C→T Polymorphism and Risk of Coronary Heart Disease

2002 • 934 citations

Homocystine-induced arteriosclerosis. The role of endothelial cell injury and platelet response in its genesis.

1976 • 933 citations

The Emerging Role of Glutamate in the Pathophysiology and Treatment of Schizophrenia

2001 • 915 citations

Neurotoxicity associated with dual actions of homocysteine at the N -methyl- <scp>d</scp> -aspartate receptor

1997 • 830 citations

Endothelial cell injury due to copper-catalyzed hydrogen peroxide generation from homocysteine.

1986 • 826 citations

Rates of Adult Schizophrenia Following Prenatal Exposure to the Chinese Famine of 1959-1961

2005 • 798 citations

Schizophrenia After Prenatal Famine

1996 • 740 citations

Schizophrenia as a Long-Term Outcome of Pregnancy, Delivery, and Perinatal Complications: A 28-Year Follow-Up of the 1966 North Finland General Population Birth Cohort

1998 • 486 citations

Childhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11

1994 • 486 citations

Plasma total cysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study

2003 • 477 citations

IQ and risk for schizophrenia: a population-based cohort study

1997 • 473 citations

Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine.

1991 • 451 citations

Activation of endogenous factor V by a homocysteine-induced vascular endothelial cell activator.

1986 • 390 citations

Obstetric complications and risk of schizophrenia

2001 • 279 citations

Fetal responses to placental insufficiency: an update

2004 • 279 citations

In utero infection and adult schizophrenia

2002 • 251 citations

Handbook of Longitudinal Research

1981 • 241 citations

Long-term behavioral and neurodegenerative effects of perinatal phencyclidine administration: implications for schizophrenia

2001 • 234 citations

Accelerated folate breakdown in pregnancy

1993 • 208 citations

Evaluating the spectrum concept of schizophrenia in the Roscommon Family Study

1995 • 190 citations

Hyperhomocyst(e)inemia and Endothelial Dysfunction in IDDM

1998 • 185 citations

Signs of asphyxia at birth and risk of schizophrenia

2001 • 175 citations

Long‐term behavioural, molecular and morphological effects of neonatal NMDA receptor antagonism

2003 • 160 citations

Elevated Homocysteine Levels in Young Male Patients With Schizophrenia

2002 • 149 citations

Elevated Plasma Homocysteine Level in Patients With Parkinson Disease

2004 • 147 citations

Folate, Homocysteine, and Negative Symptoms in Schizophrenia

2004 • 137 citations

Maternal Homocysteine before Conception and throughout Pregnancy Predicts Fetal Homocysteine and Birth Weight

2004 • 137 citations

Head Growth in Infants With Hypoxic–Ischemic Encephalopathy: Correlation With Neonatal Magnetic Resonance Imaging

2000 • 132 citations

Power Calculations for Likelihood Ratio Tests in Generalized Linear Models

1992 • 125 citations

Spatial Memory Deficits Induced by Perinatal Treatment of Rats with PCP and Reversal Effect of D-Serine

2004 • 124 citations

Maternal homocysteine and chorionic vascularization in recurrent early pregnancy loss

2000 • 121 citations

Hyperhomocysteinemia and pregnancy — review of our present understanding and therapeutic implications

2000 • 111 citations

The Design of the Prenatal Determinants of Schizophrenia Study

2000 • 106 citations

Role of homocysteine in age-related vascular and non-vascular diseases

1997 • 106 citations

Fetal alcohol syndrome at the cellular level

2004 • 106 citations

Homocysteinemia is a common feature of schizophrenia

1995 • 104 citations

Schizophrenia and impaired homocysteine metabolism: a possible association

1998 • 97 citations

Neurobiological Plausibility of Prenatal Nutritional Deprivation as a Risk Factor for Schizophrenia

1996 • 95 citations

Repeated asphyxia causes loss of striatal projection neurons in the fetal sheep brain

1995 • 92 citations

Plasma homocysteine levels elevated and inversely related to insulin sensitivity in preeclampsia

1999 • 90 citations

Maternal and fetal plasma homocysteine concentrations at birth: The influence of folate, vitamin B12, and the 5,10-methylenetetrahydrofolate reductase 677C→T variant

2002 • 87 citations

Plasma Total Homocysteine, Pregnancy Complications, and Adverse Pregnancy Outcomes: The Hordaland Homocysteine Study

2000 • 81 citations

Homocysteine Metabolism: From Basic Science to Clinical Medicine

1997 • 73 citations

Plasma Folate Adequacy as Determined by Homocysteine Level^a

1992 • 71 citations

Plasma homocysteine and the methylenetetrahydrofolate reductase C677T gene variant

1999 • 68 citations

Do Maternal Folate and Homocysteine Levels Play a Role in Neurodevelopmental Processes That Increase Risk for Schizophrenia?

2005 • 64 citations

Mild hyperhomocysteinemia is a risk-factor in all etiological subtypes of stroke

2004 • 62 citations

Homocysteine Is Lower in the Third Trimester of Pregnancy in Women with Enhanced Folate Status from Continued Folic Acid Supplementation

2004 • 62 citations

Effect of folic acid on homocysteine-induced trophoblast apoptosis

2004 • 54 citations

Genetic analysis of the thermolabile methylenetetrahydrofolate reductase variant in schizophrenia and mood disorders

2004 • 53 citations

Blockade of N-methyl-d-aspartate receptors by phencyclidine causes the loss of corticostriatal neurons

2004 • 51 citations

Homocysteine thiolactone induces apoptosis in cultured human trophoblasts: a mechanism for homocysteine-mediated placental dysfunction?

2004 • 49 citations

Changes in haemostasis during normal pregnancy: does homocysteine play a role in maintaining homeostasis?

2003 • 33 citations

Plasma total homocysteine measurement by ion-paired reversed-phase hplc with electrochemical detection

1999 • 23 citations

The California Child Health and Development Studies: twenty years of research.

1979 • 23 citations

Effects of birth insult and stress at adulthood on excitatory amino acid receptors in adult rat brain

2004 • 20 citations