Comparison of the acute effects of a selective endothelin ETA and a mixed ETA/ETB receptor antagonist in heart failure

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1988 • 10,786 citations

A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

1991 • 2,867 citations

Cloning and expression of a cDNA encoding an endothelin receptor

1990 • 2,590 citations

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Attenuation of Compensation of Endogenous Cardiac Natriuretic Peptide System in Chronic Heart Failure

1997 • 965 citations

Mechanisms regulating renin release

1976 • 886 citations

Major role of bacteria in biogeochemical fluxes in the ocean's interior

1988 • 759 citations

Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure.

1992 • 653 citations

Inhibition of myocardial endothelin pathway improves long-term survival in heart failure

1996 • 630 citations

Integrated cardiac, renal, and endocrine actions of endothelin.

1989 • 481 citations

Role of Endogenous Endothelin in Chronic Heart Failure

1997 • 367 citations

Endothelin is a potent secretagogue for atrial natriuretic peptide in cultured rat atrial myocytes

1988 • 299 citations

Increased endothelin in experimental heart failure.

1990 • 288 citations

Endothelin ET_A and ET_B receptors mediate vascular smooth muscle contraction

1992 • 286 citations

Pharmacological profile of FR139317, a novel, potent endothelin ETA receptor antagonist.

1993 • 217 citations

Relation between endothelin-1 spillover in the lungs and pulmonary vascular resistance in patients with chronic heart failure

1994 • 168 citations

Cardiorenal and neurohumoral effects of endogenous atrial natriuretic peptide in dogs with severe congestive heart failure using a specific antagonist for guanylate cyclase-coupled receptors.

1994 • 128 citations

Endothelin Adrenocortical Secretagogue Effect Is Mediated by the B Receptor in Rats

1996 • 114 citations

Clinical importance of the renin-angiotensin system in chronic heart failure: double blind comparison of captopril and prazosin.

1985 • 114 citations

Endothelin: A new inhibitor of renin release

1988 • 105 citations

Comparison of the Effects of Selective Endothelin ETaand ETbReceptor Antagonists in Congestive Heart Failure

1997 • 92 citations

Endothelin B receptor mediates ET-1 effects on cAMP and PGE2 accumulation in rat IMCD

1993 • 89 citations

Role of endothelin receptor subtypes in the in vivo regulation of renal function

1995 • 85 citations

Short-term Hemodynamic Effects of Endothelin Receptor Blockade in Dogs With Chronic Heart Failure

1996 • 74 citations

The increase in human plasma immunoreactive endothelin but not big endothelin‐1 or its C‐terminal fragment induced by systemic administration of the endothelin antagonist TAK‐044

1996 • 67 citations

A new endothelin receptor antagonist, TAK-044, shows long-lasting inhibition of both ETA- and ETB-mediated blood pressure responses in rats.

1994 • 59 citations

Endogenous atrial natriuretic peptide inhibits endothelin-1 secretion in dogs with severe congestive heart failure

1996 • 45 citations

Role of ET(A) and ET(B) receptors in endothelin-1-induced adrenal catecholamine secretion in vivo

1997 • 25 citations

Endothelin antagonists in renal disease

1997 • 9 citations

The endothelin system in the kidney

1996 • 2 citations