FireDB--a database of functionally important residues from proteins of known structure

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

1997 • 71,835 citations

MUSCLE: multiple sequence alignment with high accuracy and high throughput

2004 • 41,103 citations

Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences

2006 • 9,849 citations

T-coffee: a novel method for fast and accurate multiple sequence alignment 1 1Edited by J. Thornton

2000 • 6,765 citations

The Universal Protein Resource (UniProt)

2004 • 3,591 citations

Evolution of function in protein superfamilies, from a structural perspective 1 1Edited by A. R. Fersht

2001 • 665 citations

The Catalytic Site Atlas: a resource of catalytic sites and residues identified in enzymes using structural data

2003 • 611 citations

Databases in Protein Crystallography

1998 • 466 citations

PDBsum more: new summaries and analyses of the known 3D structures of proteins and nucleic acids

2004 • 426 citations

The Protein Data Bank and structural genomics

2003 • 395 citations

The Impact of Structural Genomics: Expectations and Outcomes

2006 • 376 citations

Relibase: Design and Development of a Database for Comprehensive Analysis of Protein–Ligand Interactions

2003 • 324 citations

dbPTM: an information repository of protein post-translational modification

2005 • 235 citations

Ligand Depot: a data warehouse for ligands bound to macromolecules

2004 • 209 citations

Automated prediction of protein function and detection of functional sites from structure

2004 • 179 citations

[30] Macromolecular crystallographic information file

1997 • 167 citations

E-MSD: an integrated data resource for bioinformatics

2003 • 156 citations

The Protein Mutant Database

1999 • 147 citations

Using a Library of Structural Templates to Recognise Catalytic Sites and Explore their Evolution in Homologous Families

2005 • 120 citations

Protein Ligand Database (PLD): additional understanding of the nature and specificity of protein–ligand complexes

2003 • 94 citations

PDBSite: a database of the 3D structure of protein functional sites

2004 • 82 citations

LigBase: a database of families of aligned ligand binding sites in known protein sequences and structures

2002 • 68 citations

Marrying structure and genomics

1998 • 67 citations

The Macromolecular Crystallographic Information File (mmCIF)

2001 • 62 citations

Predicting Reliable Regions in Protein Alignments from Sequence Profiles

2003 • 61 citations

FK506 Binding Protein Mutational Analysis

1995 • 58 citations

PDB-Ligand: a ligand database based on PDB for the automated and customized classification of ligand-binding structures

2004 • 57 citations

IUPAC—IUBMB Joint Commission on Biochemical Nomenclature (JCBN) and Nomenclature Committee of IUBMB (NC-IUBMB)

1999 • 26 citations

Assigning new GO annotations to protein data bank sequences by combining structure and sequence homology

2005 • 23 citations

The past and future of structure databases

1999 • 13 citations