Consistent loss of the D5S89 locus mapping telomeric to the interleukin gene cluster and centromeric to EGR-1 in patients with 5q- chromosome

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

Identification and characterization of the familial adenomatous polyposis coli gene

1991 • 2,806 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

Cloning of Large Segments of Exogenous DNA into Yeast by Means of Artificial Chromosome Vectors

1987 • 1,517 citations

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1990 • 1,107 citations

Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements

1988 • 984 citations

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

1979 • 905 citations

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

1988 • 883 citations

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

1991 • 758 citations

Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7.

1986 • 704 citations

Radiation Hybrid Mapping: A Somatic Cell Genetic Method for Constructing High-Resolution Maps of Mammalian Chromosomes

1990 • 630 citations

An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor

1990 • 577 citations

Anti-Oncogenic and Oncogenic Potentials of Interferon Regulatory Factors-1 and -2

1993 • 449 citations

Distinct haematological disorder with deletion of long arm of No. 5 chromosome

1974 • 432 citations

Deletion of IRF-1 , Mapping to Chromosome 5q31.1, in Human Leukemia and Preleukemic Myelodysplasia

1993 • 392 citations

The 5q− anomaly

1985 • 330 citations

Insertional mutagenesis of the myc locus by a LINE-1 sequence in a human breast carcinoma

1988 • 320 citations

Induction of the transcription factor IRF-1 and interferon-beta mRNAs by cytokines and activators of second-messenger pathways.

1989 • 292 citations

A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter.

1993 • 256 citations

Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.

1993 • 247 citations

Chromosomal Region of the Cystic Fibrosis Gene in Yeast Artificial Chromosomes: A Model for Human Genome Mapping

1990 • 238 citations

Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders

1986 • 233 citations

Lack of linkage of familial Wilms' tumour to chromosomal band 11 p13

1988 • 215 citations

Hematologic and cytologic characterization of 8/21 translocation acute granulocytic leukemia

1979 • 204 citations

Retinoblastoma: a prototypic hereditary neoplasm.

1978 • 197 citations

The interleukin 3 gene is located on human chromosome 5 and is deleted in myeloid leukemias with a deletion of 5q.

1987 • 173 citations

The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes

1992 • 164 citations

Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.

1987 • 158 citations

Interferon regulatory factor 1 is a myeloid differentiation primary response gene induced by interleukin 6 and leukemia inhibitory factor: role in growth inhibition.

1991 • 155 citations

The 5q- abnormality

1987 • 132 citations

Interleukin-5 is at 5q31 and is deleted in the 5q- syndrome

1988 • 96 citations

[17] Preparation of clone libraries in yeast artificial-chromosome vectors

1991 • 96 citations

Clinical characteristics and prognosis of 50 patients with a myeloproliferative syndrome and deletion of part of the long arm of chromosome 5

1985 • 93 citations

Chromosomal deletions in the myelodysplastic syndrome

1992 • 90 citations

A Chinese^Gγ⁺(^Aγδβ)⁰thalassemia deletion: comparison to other deletions in the human β-globin gene cluster and sequence analysis of the breakpoints

1985 • 89 citations

A Novel Interferon-Inducible Domain: Structural and Functional Analysis of the Human Interferon Regulatory Factor 1 Gene Promoter

1993 • 88 citations

Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.

1989 • 87 citations

The 5q‐ chromosome abnormality in haematological disorders:|a collaborative study of 34 cases from the Netheralands

1982 • 85 citations

A radiation hybrid map of 18 growth factor, growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5

1992 • 81 citations

Rapid identification of yeast artificial chromosome clones by matrix pooling and crude Iysate PCR

1990 • 77 citations

Chromosome study of 85 patients with myelodysplastic syndrome

1988 • 73 citations

Linkage of theleuS, emtB, andchr genes on chromosome 5 in humans and expression of human genes encoding protein synthetic components in human-Chinese hamster hybrids

1982 • 72 citations

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

1979 • 69 citations

Clinical and prognostic implications of chromosome 5q deletions: 96 high resolution studied patients.

1991 • 66 citations

Characterization of the human PIM-1 gene: a putative proto-oncogene coding for a tissue specific member of the protein kinase family.

1987 • 62 citations

A Physical Map of 15 Loci on Human Chromosome 5q23-q33 by Two-Color Fluorescence in Situ Hybridization

1993 • 61 citations

Loss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletion.

1991 • 58 citations

Report of the committee on the genetic constitution of chromosome 5

1990 • 57 citations

Radiation hybrid map of 13 loci on the long arm of chromosome 5

1991 • 48 citations

Molecular characterization of chromosome 7 long arm deletions in myeloid disorders

1987 • 48 citations

Order of genes on human chromosome 5q with respect to 5q interstitial deletions.

1990 • 44 citations

Molecular anatomy of a 5q interstitial deletion

1990 • 40 citations

Members of the RTVL-H family of human endogenous retrovirus-like elements are expressed in placenta

1989 • 39 citations

A major segment of the neurofibromatosis type 1 gene: cDNA sequence, genomic structure, and point mutations

1990 • 32 citations

Report of the committee on the genetic constitution of chromosome 3

1989 • 23 citations

Human Interferon Regulatory Factor 1: Intron-Exon Organization

1992 • 16 citations

Hematologic and cytologic characterization of 8/21 translocation acute granulocytic leukemia

1979 • 10 citations

Single copy gene detection requiring minimal cell numbers.

1989 • 9 citations

Interleukin-5 is at 5q31 and is deleted in the 5q- syndrome

1988 • 8 citations

HOMOZYGOUS DELETION OF FMS IN A PATIENT WITH THE 5q— SYNDROME

1990 • 8 citations

SstI polymorphism revealed by anonymous probe cpl 2.6 [D5S89] which maps to 5q21–5q31

1989 • 3 citations

Molecular anatomy of a 5q interstitial deletion

1990 • 3 citations