Investigation of the inhibitory effect of broussochalcone A on respiratory burst in neutrophils

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

[1] Role of free radicals and catalytic metal ions in human disease: An overview

1990 • 5,041 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Protein Kinase C: Structure, Function, and Regulation

1995 • 1,640 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977 • 865 citations

The biochemical basis of the NADPH oxidase of phagocytes

1993 • 631 citations

Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils.

1990 • 615 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase

1986 • 551 citations

Role of phosphoinositides in transmembrane signaling.

1990 • 491 citations

Phagocytosis

1974 • 392 citations

Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components.

1991 • 346 citations

Phorbol myristate acetate mediates redistribution of protein kinase C in human neutrophils: potential role in the activation of the respiratory burst enzyme.

1985 • 300 citations

Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein

1985 • 286 citations

Inhibition by islet-activating protein of a chemotactic peptide-induced early breakdown of inositol phospholipids and Ca2+ mobilization in guinea pig neutrophils.

1985 • 250 citations

Activation of the respiratory burst enzyme in human polymorphonuclear leukocytes by chemoattractants and other soluble stimuli. Evidence that the same oxidase is activated by different transductional mechanisms.

1983 • 225 citations

Metabolic, membrane, and functional responses of human polymorphonuclear leukocytes to platelet-activating factor

1982 • 177 citations

Protein kinase C isotypes and signaling in neutrophils. Differential substrate specificities of a translocatable calcium- and phospholipid-dependent beta-protein kinase C and a phospholipid-dependent protein kinase which is inhibited by long chain fatty acyl coenzyme A

1991 • 163 citations

The lipid binding, regulatory domain of protein kinase C. A 32-kDa fragment contains the calcium- and phosphatidylserine-dependent phorbol diester binding activity.

1986 • 140 citations

Superoxide release by neutrophils: Synergistic effects of a phorbol ester and a calcium ionophore

1984 • 129 citations

Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease.

1988 • 127 citations

Isozymes of protein kinase C in human neutrophils and their modification by two endogenous proteinases.

1990 • 106 citations

Rapid Assay of Binding of Tumor-Promoting Phorbol Esters to Protein Kinase C1

1986 • 84 citations

Daphnoretin-induced respiratory burst in rat neutrophils is, probably, mainly through protein kinase C activation

1995 • 65 citations

Components of Broussonetia papyrifera (L.) Vent. I. Structures of two new isoprenylated flavonols and two chalcone derivatives.

1985 • 57 citations

Inhibition by gomisin C (a lignan from Schizandra chinensis) of the respiratory burst of rat neutrophils

1994 • 47 citations

Phagocytes, Oxygen Radicals, and Lung Injury

1984 • 33 citations

Immunocharacterization of β‐ and ζ‐subspecies of protein kinase C in bovine neutrophils

1990 • 25 citations

Phenolic constituents of formosan Broussonetia papyrifera

1994 • 18 citations

Metabolic, membrane, and functional responses of human polymorphonuclear leukocytes to platelet-activating factor

1982 • 14 citations