Significant Evidence for Linkage of Mite-Sensitive Childhood Asthma to Chromosome 5q31–q33 near the Interleukin 12 B Locus by a Genome-wide Search in Japanese Families

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Linkage Analysis of IL4 and Other Chromosome 5q31.1 Markers and Total Serum Immunoglobulin E Concentrations

1994 • 1,025 citations

Patterns of single-nucleotide polymorphisms in candidate genes for blood-pressure homeostasis

1999 • 1,023 citations

Complete multipoint sib-pair analysis of qualitative and quantitative traits.

1995 • 929 citations

A genome-wide search for quantitative trait loci underlying asthma

1996 • 797 citations

Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy

1995 • 774 citations

A genome-wide search for asthma susceptibility loci in ethnically diverse populations

1997 • 712 citations

LINKAGE BETWEEN IMMUNOGLOBULIN E RESPONSES UNDERLYING ASTHMA AND RHINITIS AND CHROMOSOME 11q

1989 • 624 citations

The relative risks of sensitivity to grass pollen, house dust mite and cat dander in the development of childhood asthma

1989 • 611 citations

Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma

1998 • 396 citations

Evidence for a Locus Regulating Total Serum IgE Levels Mapping to Chromosome 5

1994 • 395 citations

Genetic Linkage of Hyper-IgE Syndrome to Chromosome 4

1999 • 387 citations

Multistage Regulation of Th1-Type Immune Responses by the Transcription Factor IRF-1

1997 • 354 citations

A Genome-wide Search for Linkage to Asthma22See the Appendix.

1999 • 351 citations

Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy.

1997 • 275 citations

Allelic association of gene markers on chromosomes 5q and 11q with atopy and bronchial hyperresponsiveness.

1996 • 263 citations

DOES T4 TOXICOSIS EXIST ?

1975 • 252 citations

Linkage of Asthma and Total Serum IgE Concentration to Markers on Chromosome 12q: Evidence from Afro-Caribbean and Caucasian Populations

1996 • 226 citations

Genetic linkage of T-cell receptor $alpha;/$delta; complex to specific IgE responses

1994 • 219 citations

Interleukin-12 inhibits antigen-induced airway hyperresponsiveness in mice.

1996 • 206 citations

Evidence for Linkage Between Asthma/Atopy in Childhood and Chromosome 5q31-q33 in a Japanese Population

1997 • 187 citations

Reduced production of IL-12 and IL-12-dependent IFN-gamma release in patients with allergic asthma.

1997 • 176 citations

Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5

1992 • 130 citations

Genetic regulation of Dermatophagoides pteronyssinus–specific IgE responsiveness: A genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs

1998 • 99 citations

Interferon regulatory factors: growth control and histone gene regulation - it's not just interferon anymore

1997 • 94 citations

Evidence for two unlinked loci regulating total serum IgE levels.

1995 • 92 citations

Linkage of Circulating Eosinophils to Markers on Chromosome 5q

1998 • 76 citations

Importance of lnterleukin-4 and lnterleukin-12 in Allergen-Induced Airway Changes in Mice

1995 • 74 citations

Linkage of Asthma to Markers on Chromosome 12 in a Sample of 240 Families Using Quantitative Phenotype Scores

1998 • 72 citations

Asthma and Bronchial Hyperresponsiveness Linked to the XY Long Arm Pseudoautosomal Region

1998 • 67 citations

Asthma in Children

1992 • 67 citations

Genetic influences of chromosomes 5q31-q33 and 11q13 on specific IgE responsiveness to common inhaled allergens among African American families

1998 • 66 citations

The role of NF-Y and IRF-2 in the regulation of human IL-4 gene expression.

1994 • 64 citations

Linkage and Association of Atopic Asthma to Markers on Chromosome 13 in the Japanese Population

1999 • 61 citations

Relative risks of bronchial hyper‐responsiveness associated with skin‐prick test responses to common antigens in young adults

1991 • 59 citations

Detection of a recessive major gene for high IgE levels acting independently of specific response to allergens

1995 • 54 citations

Administration of Interleukin‐12 Prevents Mite Der p 1 Allergen‐IgE Antibody Production and Airway Eosinophil Infiltration in an Animal Model of Airway Inflammation

1999 • 52 citations

Demonstration of a common major gene with pleiotropic effects on immunoglobulin E levels and allergy

1985 • 47 citations

High-Resolution Physical Mapping of Human 5q31-q33 Using Three Methods: Radiation Hybrid Mapping, Interphase Fluorescence in Situ Hybridization, and Pulsed-Field Gel Electrophoresis

1994 • 41 citations

HLA haplotype segregation in families with allergic asthma

1990 • 37 citations

Relation between frequency of asthma and IgE antibody levels against Dermatophagoides farinae and total serum IgE levels in schoolchildren

1988 • 36 citations

Evidence for linkage of total serum IgE and bronchial hyperresponsiveness to chromosome 5q: a major regulatory locus important in asthma

1995 • 33 citations

Linkage analysis of Dermatophagoides pteronyssinus–specific IgE responsiveness with polymorphic markers on chromosome 6p21 (HLA-D region) in Caucasian families by the transmission/disequilibrium test

1998 • 32 citations

Evidence for Linkage between the Development of Asthma in Childhood and the T-Cell Receptor β Chain Gene in Japanese

1998 • 31 citations

Interleukin-12 Inhibits Production of Interleukin-5 but Not of Granulocyte/Macrophage Colony-Stimulating Factor by Antigen-Stimulated Blood Mononuclear Cells in Allergic Bronchial Asthmatics

1997 • 20 citations

Regulation of the interferon system, immune response and oncogenesis by the transcription factor interferon regulatory factor-1.

1998 • 18 citations

NF-Y, IRF-2, and C/EBP Proteins are Involved in Regulation of Human IL-4 Gene Expression

1995 • 1 citations

Deleted Work

1955 • 0 citations