Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice

The Response-to-Retention Hypothesis of Early Atherogenesis

1995 • 1,365 citations

CD36 is a receptor for oxidized low density lipoprotein

1993 • 1,271 citations

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1997 • 1,210 citations

Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice

2000 • 1,020 citations

Subendothelial retention of atherogenic lipoproteins in early atherosclerosis

2002 • 979 citations

Scavenger Receptors Class A-I/II and CD36 Are the Principal Receptors Responsible for the Uptake of Modified Low Density Lipoprotein Leading to Lipid Loading in Macrophages

2002 • 947 citations

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways

2004 • 624 citations

Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins.

1979 • 545 citations

The scavenger cell pathway for lipoprotein degradation: Specificity of the binding site that mediates the uptake of negatively‐charged LDL by macrophages

1980 • 543 citations

The role of PPAR-γ in macrophage differentiation and cholesterol uptake

2001 • 507 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

Role of Lipoprotein-Associated Phospholipase A ₂ in Atherosclerosis

2005 • 458 citations

CD36 Mediates the Innate Host Response to β-Amyloid

2003 • 448 citations

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.

1990 • 360 citations

Oxidized low-density lipoprotein-induced apoptosis

2002 • 323 citations

A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid

2002 • 315 citations

Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice

2003 • 311 citations

Macropinocytosis Is the Endocytic Pathway That Mediates Macrophage Foam Cell Formation with Native Low Density Lipoprotein

2004 • 266 citations

Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice

2003 • 255 citations

Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.

1994 • 248 citations

Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.

1991 • 214 citations

Increased atherosclerosis in streptozotocin-induced diabetic mice.

1996 • 182 citations

Low density lipoprotein metabolism by human macrophages activated with low density lipoprotein immune complexes. A possible mechanism of foam cell formation.

1988 • 174 citations

Genetic Background Determines the Extent of Atherosclerosis in ApoE-Deficient Mice

1999 • 168 citations

Stem Cell Transplantation Reveals That Absence of Macrophage CD36 Is Protective Against Atherosclerosis

2004 • 166 citations

Reduced Atherosclerotic Lesions in Mice Deficient for Total or Macrophage-Specific Expression of Scavenger Receptor-A

2000 • 159 citations

Macrophage Foam Cell Formation with Native Low Density Lipoprotein

2002 • 157 citations

LDL Receptor–Related Protein Mediates Uptake of Aggregated LDL in Human Vascular Smooth Muscle Cells

2000 • 151 citations

Role of macrophage scavenger receptors in diet-induced atherosclerosis in mice.

1998 • 144 citations

Fibrillar Amyloid Protein Present in Atheroma Activates CD36 Signal Transduction

2004 • 135 citations

Accumulation of Biglycan and Perlecan, but Not Versican, in Lesions of Murine Models of Atherosclerosis

2002 • 113 citations

Sequestration of aggregated low-density lipoproteins by macrophages

2002 • 109 citations

Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice

1999 • 99 citations

Lipoprotein-antibody immune complexes their catabolism and role in foam cell formation

1985 • 97 citations

Macrophage foam cells and atherosclerosis

2001 • 90 citations

Genetic Background Selectively Influences Innominate Artery Atherosclerosis

2003 • 75 citations

Low-density lipoprotein concentration in interstitial fluid from human atherosclerotic lesions

1983 • 70 citations

Effect of Human Scavenger Receptor Class A Overexpression in Bone Marrow–Derived Cells on Cholesterol Levels and Atherosclerosis in ApoE-Deficient Mice

2000 • 62 citations

Aggregated Low Density Lipoprotein Induces and Enters Surface-connected Compartments of Human Monocyte-Macrophages

1997 • 60 citations

Macrophage-specific expression of class A scavenger receptors in LDL receptor−/− mice decreases atherosclerosis and changes spleen morphology

2002 • 55 citations

Ceramide in Lipid Particles Enhances Heparan Sulfate Proteoglycan and Low Density Lipoprotein Receptor-related Protein-mediated Uptake by Macrophages

2004 • 51 citations

Low-Density Lipoprotein From Apolipoprotein E-Deficient Mice Induces Macrophage Lipid Accumulation in a CD36 and Scavenger Receptor Class A-Dependent Manner

2004 • 51 citations

Effect of human scavenger receptor class A overexpression in bone marrow-derived cells on lipoprotein metabolism and atherosclerosis in low density lipoprotein receptor knockout mice

2000 • 50 citations

Lipoprotein concentrations in serum and in biopsy samples of arterial intima A quantitative comparison

1976 • 43 citations

Macrophage foam cells and atherosclerosis

2001 • 30 citations

Scavenger Receptor Activity Is Increased in Macrophages From Rabbits With Low Atherosclerotic Response:

1999 • 27 citations

Hepatic overexpression of bovine scavenger receptor type I in transgenic mice prevents diet-induced hyperbetalipoproteinemia.

1995 • 21 citations

Scavenger receptor activity and expression of apolipoprotein E mRNA in monocyte-derived macrophages of young and old healthy men

1997 • 19 citations

Transgenic mouse models to study the role of the macrophage scavenger receptor class A in atherosclerosis.

2000 • 16 citations