Inhibition of NF-κB activation in macrophages increases atherosclerosis in LDL receptor–deficient mice

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Inflammation in atherosclerosis

2002 • 7,873 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

Atherosclerosis

2000 • 4,558 citations

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

1999 • 1,987 citations

Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB

1995 • 1,849 citations

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

1993 • 1,578 citations

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

1999 • 1,381 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

1999 • 922 citations

Protective Role of Interleukin-10 in Atherosclerosis

1999 • 805 citations

Activated transcription factor nuclear factor-kappa B is present in the atherosclerotic lesion.

1996 • 795 citations

Possible new role for NF-κB in the resolution of inflammation

2001 • 741 citations

NF-κB: pivotal mediator or innocent bystander in atherogenesis?

2001 • 729 citations

Expression of Toll-Like Receptors in Human Atherosclerotic Lesions

2002 • 669 citations

Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice

1999 • 581 citations

Decrease in reactive amino groups during oxidation or endothelial cell modification of LDL. Correlation with changes in receptor-mediated catabolism.

1987 • 473 citations

TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

2002 • 465 citations

NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

2000 • 435 citations

Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic mice.

1994 • 248 citations

Macrophage Class A Scavenger Receptor-Mediated Phagocytosis ofEscherichia coli: Role of Cell Heterogeneity, Microbial Strain, and Culture Conditions In Vitro

2000 • 228 citations

Accelerated Atherosclerosis in Mice Lacking Tumor Necrosis Factor Receptor p55

1996 • 183 citations

IκB Kinase Signaling Is Essential for Maintenance of Mature B Cells

2002 • 179 citations

Autocrine Deactivation of Macrophages in Transgenic Mice Constitutively Overexpressing IL-10 Under Control of the Human CD68 Promoter

2002 • 175 citations

Loss of Lymphotoxin-α but Not Tumor Necrosis Factor-α Reduces Atherosclerosis in Mice

2002 • 140 citations

Detection of B Cells and Proinflammatory Cytokines in Atherosclerotic Plaques of Hypercholesterolaemic Apolipoprotein E Knockout Mice

1999 • 139 citations

Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17β-estradiol in apolipoprotein E-deficient mice

2001 • 121 citations

Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice

1999 • 99 citations

Optimal conditions for proliferation of bone marrow‐derived mouse macrophages in culture: The roles of CSF‐1, serum, Ca²⁺, and adherence

1983 • 94 citations

Progression and regression of atherosclerosis in APOE3-Leiden transgenic mice: an immunohistochemical study

1999 • 80 citations

Lipoprotein lipase stimulates the binding and uptake of moderately oxidized low-density lipoprotein by J774 macrophages

1996 • 57 citations

Autocrine and Exocrine Regulation of Interleukin-10 Production in THP-1 Cells Stimulated withBorrelia burgdorferiLipoproteins

2002 • 51 citations