Genetic footprinting with mariner -based transposition in Pseudomonas aeruginosa

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A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

The changing epidemiology of cystic fibrosis

1993 • 930 citations

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1996 • 911 citations

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1994 • 886 citations

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Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells

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Chromosomal genetics of Pseudomonas

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1990 • 670 citations

Microbiology of airway disease in patients with cystic fibrosis

1991 • 531 citations

A purified mariner transposase is sufficient to mediate transposition in vitro.

1996 • 452 citations

Induction of Homologous Recombination in Mammalian Chromosomes by Using the I-SceI System of Saccharomyces cerevisiae

1995 • 438 citations

Plasmid vectors for the genetic analysis and manipulation of rhizobia and other gram-negative bacteria

1986 • 381 citations

The response of Pseudomonas aeruginosa to iron: genetics, biochemistry and virulence

1999 • 364 citations

In vivo transposition of mariner -based elements in enteric bacteria and mycobacteria

1999 • 349 citations

An improved system for gene replacement and xylE fusion analysis in Pseudomonas aeruginosa

1995 • 344 citations

Introduction of Double-Strand Breaks into the Genome of Mouse Cells by Expression of a Rare-Cutting Endonuclease

1994 • 321 citations

Alielic exchange in Pseudomonas aeruginosa using novel ColE1‐type vectors and a family of cassettes containing a portable oriT and the counter‐selectable Bacillus subtilis sacB marker

1992 • 288 citations

Systematic identification of essential genes by in vitro mariner mutagenesis

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Universal code equivalent of a yeast mitochondrial intron reading frame is expressed into E. coli as a specific double strand endonuclease

1986 • 266 citations

Homologous recombination in plant cells is enhanced byin vivoinduction of double strand breaks into DNA by a site-specific endonuclease

1993 • 266 citations

Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleus.

1992 • 225 citations

Improved Broad-Host-Range RK2 Vectors Useful for High and Low Regulated Gene Expression Levels in Gram-Negative Bacteria

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Purification and characterization of thein vitroactivity of I-SceI, a novel and highly specific endonuclease encoded by a group I intron

1990 • 167 citations

cumA , a Gene Encoding a Multicopper Oxidase, Is Involved in Mn ²⁺ Oxidation in Pseudomonas putida GB-1

1999 • 166 citations

Genetic footprinting: a genomic strategy for determining a gene's function given its sequence.

1995 • 162 citations

Mini-Tn10 transposon derivatives for insertion mutagenesis and gene delivery into the chromosome of Gram-negative bacteria

1995 • 105 citations

Analysis of an Escherichia coli mutant strain resistant to the cell‐killing function encoded by the gef gene family

1992 • 30 citations

Orotidine-5′-monophosphate decarboxylase fromPseudomonas aeruginosa PAO1: Cloning, overexpression, and enzyme characterization

1994 • 8 citations

A NewBradyrhizobium japonicumGene Required for Free-Living Growth and Bacteroid Development Is Conserved in Other Bacteria and in Plants

1995 • 6 citations