Protein-tyrosine Phosphatase (PTP) Wedge Domain Peptides

Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling

1995 • 2,907 citations

Trk Receptors: Roles in Neuronal Signal Transduction

2003 • 2,410 citations

The protein Id: A negative regulator of helix-loop-helix DNA binding proteins

1990 • 2,273 citations

Neurotrophin signal transduction in the nervous system

2000 • 1,910 citations

Helix-Loop-Helix Proteins: Regulators of Transcription in Eucaryotic Organisms

2000 • 1,761 citations

Signaling Pathways for PC12 Cell Differentiation: Making the Right Connections

2002 • 788 citations

Id proteins in development, cell cycle and cancer

2003 • 565 citations

Combinatorial control of the specificity of protein tyrosine phosphatases

2001 • 500 citations

Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro

1987 • 486 citations

Protein transduction technology

2002 • 483 citations

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains.

1996 • 452 citations

Protein Tyrosine Phosphatases: Structure and Function, Substrate Specificity, and Inhibitor Development

2002 • 426 citations

Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases

2001 • 385 citations

Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.

1990 • 365 citations

Structural basis for inhibition of receptor protein-tyrosine phosphatase-α by dimerization

1996 • 324 citations

Liprins, a Family of LAR Transmembrane Protein-tyrosine Phosphatase-interacting Proteins

1998 • 288 citations

A Novel Neurotrophic Property of Glucagon-Like Peptide 1: A Promoter of Nerve Growth Factor-Mediated Differentiation in PC12 Cells

2002 • 284 citations

Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation

1993 • 268 citations

Receptor Protein Tyrosine Phosphatases in Nervous System Development

2003 • 223 citations

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells

1999 • 221 citations

Peptide modulators of protein–protein interactions in intracellular signaling

1998 • 216 citations

Crystal Structure of the Tandem Phosphatase Domains of RPTP LAR

1999 • 174 citations

Caveolin Interacts with Trk A and p75NTR and Regulates Neurotrophin Signaling Pathways

1999 • 163 citations

In vitro assay to test differential substrate affinities of growing axons and migratory cells

1990 • 136 citations

The Transmembrane Protein-tyrosine Phosphatase LAR Modulates Signaling by Multiple Receptor Tyrosine Kinases

1996 • 130 citations

PTPμ Regulates N-Cadherin–dependent Neurite Outgrowth

1999 • 120 citations

The Crystal Structure of Domain 1 of Receptor Protein-tyrosine Phosphatase μ

1997 • 115 citations

Deficient LAR expression decreases basal forebrain cholinergic neuronal size and hippocampal cholinergic innervation

1997 • 114 citations

Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu.

1994 • 112 citations

The Second Catalytic Domain of Protein Tyrosine Phosphatase δ (PTPδ) Binds to and Inhibits the First Catalytic Domain of PTPς

1998 • 102 citations

SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase

2003 • 91 citations

Receptor protein tyrosine phosphatases regulate neural development and axon guidance

2004 • 86 citations

LAR tyrosine phosphatase receptor: alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats.

1995 • 79 citations

The Leukocyte Common Antigen-Related Protein Tyrosine Phosphatase Receptor Regulates Regenerative Neurite OutgrowthIn Vivo

2001 • 75 citations

Intra- and Intermolecular Interactions between Intracellular Domains of Receptor Protein-tyrosine Phosphatases

2002 • 73 citations

Multiple Levels for Regulation of TrkA in PC12 Cells by Nerve Growth Factor

1995 • 71 citations

Receptor tyrosine phosphatases in axon growth and guidance

2001 • 70 citations

Leukocyte common antigen-related receptor-linked tyrosine phosphatase. Regulation of mRNA expression.

1993 • 68 citations

Some protein tyrosine phosphatases target in part to lipid rafts and interact with caveolin-1

2002 • 67 citations

Changes in extracellular potassium concentration in cat spinal cord in response to innocuous and noxious stimulation of legs with healthy and inflamed knee joints

1990 • 66 citations

A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration.

1996 • 62 citations

Multiple Interactions between Receptor Protein-tyrosine Phosphatase (RPTP) α and Membrane-distal Protein-tyrosine Phosphatase Domains of Various RPTPs

2000 • 59 citations

Leukocyte Antigen-Related Protein Tyrosine Phosphatase Receptor: A Small Ectodomain Isoform Functions as a Homophilic Ligand and Promotes Neurite Outgrowth

2003 • 53 citations

LAR Tyrosine Phosphatase Receptor: A Developmental Isoform Is Present in Neurites and Growth Cones and Its Expression Is Regional- and Cell-Specific

1998 • 45 citations

Delayed peripheral nerve regeneration and central nervous system collateral sprouting in leucocyte common antigen‐related protein tyrosine phosphatase‐deficient mice

2003 • 44 citations

Downregulation of LAR tyrosine phosphatase prevents apoptosis and augments NGF-induced neurite outgrowth

2000 • 41 citations

Oligomerization Mediated by a Helix-Loop-Helix-Like Domain of Baculovirus IE1 Is Required for Early Promoter Transactivation

2001 • 40 citations

Regulatory Mechanisms for Receptor Protein Tyrosine Phosphatases

2001 • 39 citations

Receptor tyrosine phosphatases in axon growth and guidance

2000 • 38 citations

Protein Tyrosine Phosphatase-μ Differentially Regulates Neurite Outgrowth of Nasal and Temporal Neurons in the Retina

2002 • 35 citations

Pattern of distribution and co-localization of NOS and ATP in the myenteric plexus of human fetal stomach and intestine

2000 • 31 citations

Intramolecular Interactions between the Juxtamembrane Domain and Phosphatase Domains of Receptor Protein-tyrosine Phosphatase RPTPμ

2000 • 30 citations

Sequence specific peptidomimetic molecules inhibitors of a protein–protein interaction at the helix 1 level of c‐Myc

2005 • 28 citations

PTPμ signaling via PKCδ is instructive for retinal ganglion cell guidance

2004 • 27 citations

Determinants of Helix-Loop-Helix Dimerization Affinity

1996 • 24 citations

PTPμ expression and catalytic activity are required for PTPμ-mediated neurite outgrowth and repulsion

2004 • 22 citations

PTPμ‐dependent growth cone rearrangement is regulated by Cdc42

2003 • 14 citations

Nerve growth factor regulates neuroectodermal tumor cell responses to mitogenic growth factors

2003 • 4 citations