PTPμ signaling via PKCδ is instructive for retinal ganglion cell guidance

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

The Molecular Biology of Axon Guidance

1996 • 3,246 citations

Protein Kinase C: Structural and Spatial Regulation by Phosphorylation, Cofactors, and Macromolecular Interactions

2001 • 966 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

The Neural Cell Adhesion Molecule (NCAM) as a Regulator of Cell-Cell Interactions

1988 • 790 citations

Conversion of Neuronal Growth Cone Responses from Repulsion to Attraction by Cyclic Nucleotides

1998 • 784 citations

Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins.

1994 • 715 citations

cAMP-induced switching in turning direction of nerve growth cones

1997 • 614 citations

Signal Transduction in Neuronal Migration

2001 • 541 citations

Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

2001 • 540 citations

Mechanisms and Molecules that Control Growth Cone Guidance

1996 • 515 citations

Identification of intracellular receptor proteins for activated protein kinase C.

1991 • 505 citations

Cyclic AMP-specific PDE4 Phosphodiesterases as Critical Components of Cyclic AMP Signaling

2003 • 486 citations

Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro

1987 • 486 citations

An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension.

1987 • 464 citations

Ephrin-A5 Induces Collapse of Growth Cones by Activating Rho and Rho Kinase

2000 • 393 citations

Cyclic AMP/GMP-dependent modulation of Ca2+ channels sets the polarity of nerve growth-cone turning

2003 • 374 citations

A Protein Kinase C Translocation Inhibitor as an Isozyme-selective Antagonist of Cardiac Function

1996 • 371 citations

Avoidance of posterior tectal membranes by temporal retinal axons

1987 • 370 citations

Adaptor proteins in protein kinase C-mediated signal transduction

2001 • 352 citations

Membrane glycoproteins involved in neurite fasciculation.

1987 • 347 citations

Neural Cell Adhesion Molecule-Stimulated Neurite Outgrowth Depends on Activation of Protein Kinase C and the Ras–Mitogen-Activated Protein Kinase Pathway

2000 • 328 citations

Phosphorylation of Collapsin Response Mediator Protein-2 by Rho-kinase

2000 • 315 citations

Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo.

1995 • 313 citations

The enrichment of a neuronal growth cone collapsing activity from embryonic chick brain

1990 • 279 citations

Turning of nerve growth cones induced by localized increases in intracellular calcium ions

2000 • 278 citations

Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation

1993 • 268 citations

Protein kinase C binding partners

2000 • 264 citations

Receptor Protein Tyrosine Phosphatases in Nervous System Development

2003 • 223 citations

Nerve growth cone guidance mediated by G protein–coupled receptors

2002 • 222 citations

Neurite growth on different substrates: permissive versus instructive influences and the role of adhesive strength

1992 • 217 citations

Axonal guidance in the chick visual system: Posterior tectal membanes induce collapse of growth cones from the temporal retina

1990 • 208 citations

Translocation Inhibitors Define Specificity of Protein Kinase C Isoenzymes in Pancreatic β-Cells

1997 • 173 citations

FGF signaling and target recognition in the developing xenopus visual system

1995 • 168 citations

Distinct Neurite Outgrowth Signaling Pathways Converge on ERK Activation

1999 • 168 citations

The role of cell adhesion molecules in neurite outgrowth on Müller cells

1990 • 164 citations

Dynamic Interaction of PTPμ with Multiple Cadherins In Vivo

1998 • 157 citations

Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse

1995 • 148 citations

Drosophila LAR Regulates R1-R6 and R7 Target Specificity in the Visual System

2001 • 141 citations

Inhibition of FGF Receptor Activity in Retinal Ganglion Cell Axons Causes Errors in Target Recognition

1996 • 139 citations

In vitro assay to test differential substrate affinities of growing axons and migratory cells

1990 • 136 citations

Retinal Axon Target Selection in Drosophila Is Regulated by a Receptor Protein Tyrosine Phosphatase

1999 • 135 citations

Cell-Autonomous and -Nonautonomous Functions of LAR in R7 Photoreceptor Axon Targeting

2001 • 124 citations

PTPμ Regulates N-Cadherin–dependent Neurite Outgrowth

1999 • 120 citations

Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms.

1990 • 116 citations

Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu.

1994 • 112 citations

Development of the visual system of the chick

2001 • 111 citations

The PTPμ Protein-tyrosine Phosphatase Binds and Recruits the Scaffolding Protein RACK1 to Cell-Cell Contacts

2001 • 107 citations

Protein Kinase C Activation Promotes Microtubule Advance in Neuronal Growth Cones by Increasing Average Microtubule Growth Lifetimes

2001 • 100 citations

Oriented axon outgrowth from avian embryonic retinae in culture

1983 • 98 citations

Ephrins regulate the formation of terminal axonal arbors during the development of thalamocortical projections

2002 • 87 citations

Cell signalling cascades regulating neuronal growth-promoting and inhibitory cues

2001 • 84 citations

The Receptor-like Protein-tyrosine Phosphatase, RPTPα, Is Phosphorylated by Protein Kinase C on Two Serines Close to the Inner Face of the Plasma Membrane

1995 • 78 citations

Growth cone behavior on gradients of substratum bound laminin

1988 • 72 citations

Manipulation of EphB2 Regulatory Motifs and SH2 Binding Sites Switches MAPK Signaling and Biological Activity

2003 • 71 citations

How do Rho family GTPases direct axon growth and guidance? A proposal relating signaling pathways to growth cone mechanics

2002 • 70 citations

In the eye of the beholder

2003 • 68 citations

Opposing Effects of δ and ξ PKC in Ethanol-induced Cardioprotection

2001 • 59 citations

Complex Genetic Interactions among Four Receptor Tyrosine Phosphatases Regulate Axon Guidance in Drosophila

2001 • 58 citations

Protein Kinase C δ (PKCδ) Is Required for Protein Tyrosine Phosphatase μ (PTPμ)-Dependent Neurite Outgrowth

2002 • 52 citations

PKC is required for activation of ROCK by RhoA in human endothelial cells

2003 • 47 citations

A Soluble Version of the Receptor-like Protein Tyrosine Phosphatase κ Stimulates Neurite Outgrowth via a Grb2/MEK1-Dependent Signaling Cascade

1999 • 45 citations

Growth Cone Steering by Receptor Tyrosine Phosphatase δ Defines a Distinct Class of Guidance Cue

2000 • 43 citations

CRYP-2/cPTPRO is a neurite inhibitory repulsive guidance cue for retinal neurons in vitro

2001 • 42 citations

Regulation of retinal neurite growth by alterations in MAPK/ERK kinase (MEK) activity

2000 • 38 citations

Physical and Functional Interactions between Protein Tyrosine Phosphatase α, PI 3-Kinase, and PKCδ

2001 • 37 citations

Fibroblast growth factors redirect retinal axons in vitro and in vivo

2003 • 37 citations

Protein kinase C mediates neurite guidance at an astrocyte boundary

2001 • 35 citations

Protein Tyrosine Phosphatase-μ Differentially Regulates Neurite Outgrowth of Nasal and Temporal Neurons in the Retina

2002 • 35 citations

Eicosanoid Activation of Protein Kinase C ϵ

2003 • 33 citations

Purification and characterization of the human protein tyrosine phosphatase, PTP?, from a baculovirus expression system

1993 • 19 citations

The receptor protein tyrosine phosphatase mu, PTPμ, regulates histogenesis of the chick retina

2003 • 14 citations

PTPμ‐dependent growth cone rearrangement is regulated by Cdc42

2003 • 14 citations

Purification and characterization of the human protein tyrosine phosphatase, PTPμ, from a baculovirus expression system

1993 • 8 citations