Exploiting different ways to die: Figure 1.

The Hallmarks of Cancer

2000 • 27,569 citations

Cell Death

2004 • 4,599 citations

Development by Self-Digestion

2004 • 3,562 citations

Autophagy as a Regulated Pathway of Cellular Degradation

2000 • 3,453 citations

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1999 • 3,194 citations

Apoptosis

2002 • 2,190 citations

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

2003 • 2,136 citations

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

2003 • 2,041 citations

The Bcl-2 family: roles in cell survival and oncogenesis

2003 • 1,448 citations

Ways of dying: multiple pathways to apoptosis

2003 • 786 citations

The Role of Apoptosis in Creating and Maintaining Luminal Space within Normal and Oncogene-Expressing Mammary Acini

2002 • 763 citations

Necrosis: a specific form of programmed cell death?

2003 • 710 citations

Alkylating DNA damage stimulates a regulated form of necrotic cell death

2004 • 618 citations

Is Cisplatin-Induced Cell Death Always Produced by Apoptosis?

2001 • 556 citations

The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis

1994 • 428 citations

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro

2004 • 238 citations

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

2003 • 213 citations

Cancer Therapy with ß-Lapachone

2002 • 209 citations

BAX and BAK mediate p53-independent suppression of tumorigenesis

2002 • 135 citations

Targeting Bcl-2 Related Proteins in Cancer Therapy

2003 • 86 citations

Inhibition of platelet-derived growth factor signalling induces autophagy in malignant glioma cells

2004 • 69 citations

Tumor Cells Utilize Multiple Pathways to Down‐modulate Apoptosis: Lessons from a Mouse Model of Islet Cell Carcinogenesis

1999 • 46 citations

Bcl-2 accelerates multistep prostate carcinogenesis in vivo

2000 • 43 citations