Afferent Arteriolar Vasodilation to the Sulfonimide Analog of 11,12-Epoxyeicosatrienoic Acid Involves Protein Kinase A

Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells.

1990 • 1,507 citations

Identification of Epoxyeicosatrienoic Acids as Endothelium-Derived Hyperpolarizing Factors

1996 • 1,226 citations

Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.

1993 • 713 citations

Characterization of endothelium‐derived hyperpolarizing factor as a cytochrome P450‐derived arachidonic acid metabolite in mammals.

1994 • 430 citations

Role of Cytochrome P-450 Enzymes and Metabolites of Arachidonic Acid in the Control of Vascular Tone

1995 • 302 citations

Primary Structural Determinants Essential for Potent Inhibition of cAMP-dependent Protein Kinase by Inhibitory Peptides Corresponding to the Active Portion of the Heat-Stable Inhibitor Protein

1989 • 278 citations

Epoxyeicosatrienoic Acids Activate K ⁺ Channels in Coronary Smooth Muscle Through a Guanine Nucleotide Binding Protein

1997 • 262 citations

Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: characterization of selective inhibitors.

1998 • 234 citations

Actions of epoxygenase metabolites on the preglomerular vasculature.

1996 • 206 citations

Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid

1993 • 196 citations

Towards an Understanding of the Mechanism of Action of Cyclic AMP and Cyclic GMP in Smooth Muscle Relaxation

1991 • 191 citations

Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet.

1994 • 190 citations

Stereospecific effects of epoxyeicosatrienoic acids on renal vascular tone and K(+)-channel activity

1996 • 182 citations

Inhibition of renal vascular 20-HETE production impairs autoregulation of renal blood flow

1994 • 158 citations

Cytochrome P-450 arachidonic acid epoxygenase. Regulatory control of the renal epoxygenase by dietary salt loading.

1992 • 151 citations

Epoxyeicosatrienoic Acids and Their Sulfonimide Derivatives Stimulate Tyrosine Phosphorylation and Induce Mitogenesis in Renal Epithelial Cells

1998 • 134 citations

An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells.

1991 • 122 citations

Contribution of NO and cytochrome P450 to the vasodilator effect of bradykinin in the rat kidney

1992 • 121 citations

Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites.

1992 • 106 citations

Regulation of Potassium Channels in Coronary Arterial Smooth Muscle by Endothelium-Derived Vasodilators

1997 • 105 citations

Cytochrome P450: a novel system modulating Ca²⁺ channels and contraction in mammalian heart cells

1998 • 100 citations

Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 arachidonic acid epoxygenase

1993 • 97 citations

Epoxyeicosatrienoic acids, potassium channel blockers and endothelium‐dependent hyperpolarization in the guinea‐pig carotid artery

1998 • 95 citations

Contribution of 20-HETE to the vasodilator actions of nitric oxide in renal arteries

1998 • 90 citations

Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses

1990 • 83 citations

Renal cytochrome P-450-dependent metabolism of arachidonic acid in spontaneously hypertensive rats

1988 • 79 citations

Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney

1991 • 71 citations

5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis

1995 • 62 citations

[40] Synthesis of epoxyeicosatrienoic acids and heteroatom analogs

1990 • 60 citations

Synthesis and biological activity of carboxyl-terminus modified prostaglandin analogs

1979 • 59 citations

Role of Cytochrome P-450 in Elevating Renal Vascular Tone in Spontaneously Hypertensive Rats

1993 • 55 citations

Differential responses of cyclic GMP-dependent and cyclic AMP-dependent protein kinases to synthetic peptide inhibitors

1983 • 52 citations

Newborn piglet cerebral microvascular responses to epoxyeicosatrienoic acids

1997 • 50 citations

Cytochrome P-450-dependent vasodilator responses to arachidonic acid in the isolated, perfused kidney of the rat.

1991 • 40 citations

Contribution of constrictor prostanoids to the calcium-dependent basal tone in the aorta from rats with aortic coarctation-induced hypertension: relationship to nitric oxide.

1997 • 24 citations

Endothelium-Derived Hyperpolarizing Factor, But Not Nitric Oxide, Is Reversibly Inhibited by Brefeldin A

1997 • 17 citations

Afferent arteriolar response to arachidonic acid: involvement of metabolic pathways

1996 • 16 citations

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