Identification of SH2-Bβ as a potent cytoplasmic activator of the tyrosine kinase Janus kinase 2

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

STATs and Gene Regulation

1997 • 3,927 citations

A family of cytokine-inducible inhibitors of signalling

1997 • 2,055 citations

STATs: Signal Transducers and Activators of Transcription

1996 • 1,414 citations

A new protein containing an SH2 domain that inhibits JAK kinases

1997 • 1,413 citations

Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses

1998 • 1,316 citations

Structure and function of a new STAT-induced STAT inhibitor

1997 • 1,308 citations

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

1993 • 1,223 citations

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

1998 • 1,155 citations

Stat5a is mandatory for adult mammary gland development and lactogenesis.

1997 • 1,106 citations

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1997 • 989 citations

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

1993 • 988 citations

Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis

1998 • 904 citations

Jaks and Stats in signaling by the cytokine receptor superfamily

1995 • 902 citations

High-Efficiency Transformation of Mammalian Cells by Plasmid DNA

1987 • 729 citations

Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation

1998 • 666 citations

Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription.

1994 • 599 citations

Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.

1993 • 516 citations

Mechanism of signaling by growth hormone receptor

1996 • 264 citations

Growth Hormone, Interferon-γ, and Leukemia Inhibitory Factor Promoted Tyrosyl Phosphorylation of Insulin Receptor Substrate-1

1995 • 246 citations

Activation of JAK2 tyrosine kinase by prolactin receptors in Nb2 cells and mouse mammary gland explants.

1994 • 225 citations

Identification and Characterization of Novel Substrates of Trk Receptors in Developing Neurons

1998 • 224 citations

The Janus Protein Tyrosine Kinase Family and Its Role in Cytokine Signaling

1995 • 217 citations

The role of the growth hormone (GH) receptor and JAK1 and JAK2 kinases in the activation of Stats 1, 3, and 5 by GH.

1996 • 198 citations

Activation of Acute Phase Response Factor (APRF)/Stat3 Transcription Factor by Growth Hormone

1995 • 180 citations

Identification of SH2-Bβ as a Substrate of the Tyrosine Kinase JAK2 Involved in Growth Hormone Signaling

1997 • 175 citations

Proline-rich Sequence-mediated Jak2 Association to the Prolactin Receptor Is Required but Not Sufficient for Signal Transduction

1995 • 172 citations

Growth Hormone-promoted Tyrosyl Phosphorylation of SHC Proteins and SHC Association with Grb2

1995 • 168 citations

The Yeast Tribrid System—Genetic Detection of trans-phosphorylated ITAM-SH2-Interactions

1995 • 157 citations

Growth Hormone, Interferon-γ, and Leukemia Inhibitory Factor Utilize Insulin Receptor Substrate-2 in Intracellular Signaling

1996 • 120 citations

In vivo growth hormone treatment rapidly stimulates the tyrosine phosphorylation and activation of Stat3.

1995 • 106 citations

Growth Hormone Regulation of SIRP and SHP-2 Tyrosyl Phosphorylation and Association

1998 • 100 citations

Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase.

1996 • 90 citations

SH2-B Is Required for Nerve Growth Factor-induced Neuronal Differentiation

1999 • 88 citations

A Functional DNA Binding Domain Is Required for Growth Hormone-induced Nuclear Accumulation of Stat5B

1999 • 79 citations

Janus kinases in cytokine signalling

1996 • 73 citations

Insulin-like Growth Factor-I Receptor and Insulin Receptor Association with a Src Homology-2 Domain-containing Putative Adapter

1998 • 72 citations

Growth Hormone-Induced Tyrosyl Phosphorylation and Deoxyribonucleic Acid Binding Activity of Stat5A and Stat5B*

1997 • 71 citations

Platelet-derived Growth Factor (PDGF) Stimulates the Association of SH2-Bβ with PDGF Receptor and Phosphorylation of SH2-Bβ

1998 • 65 citations

Evidence for association of the cloned liver growth hormone receptor with a tyrosine kinase.

1992 • 34 citations