Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism.

Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide

1963 • 7,266 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Rapid analysis of amino acids using pre-column derivatization

1984 • 2,491 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

1990 • 997 citations

GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies.

1989 • 993 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

An SN2 deprotection of synthetic peptides with a low concentration of hydrofluoric acid in dimethyl sulfide: evidence and application in peptide synthesis

1983 • 545 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 538 citations

GMP-140 mediates adhesion of stimulated platelets to neutrophils

1990 • 515 citations

A monoclonal antibody to a membrane glycoprotein binds only to activated platelets.

1984 • 456 citations

Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.

1992 • 178 citations

Characterization of the enhanced adhesion of neutrophil leukocytes to thrombin-stimulated endothelial cells.

1990 • 163 citations

Pulmonary microembolism

1983 • 158 citations

Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.

1992 • 146 citations

Structural and Biosynthetic Studies of the Granule Membrane Protein, GMP-140, from Human Platelets and Endothelial Cells

1989 • 107 citations

A 14 amino acid peptide derived from the amino terminus of the cleaved thrombin receptor elevates intracellular calcium and stimulates prostacyclin production in human endothelial cells

1991 • 90 citations

Thrombin‐induced adherence of neutrophils to cultured endothelial monolayers: Increased endothelial adhesiveness

1988 • 57 citations

Solid phase peptide synthesis

2002 • 54 citations

GMP-140 mediates adhesion of stimulated platelets to neutrophils

1990 • 44 citations

Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients

1992 • 42 citations

PADGEM (GMP140) is a component of Weibel-Palade bodies of human endothelial cells

1989 • 41 citations

Phenotypes of Cultured Endothelium: Expression of Angiotensin-Converting Enzyme Activity1

2015 • 15 citations