Transcriptional Regulation of a Mouse Clara Cell-Specific Protein (mCC10) Gene by the NKx Transcription Factor Family Members Thyroid Transcription Factor 1 and Cardiac Muscle-Specific Homeobox Protein (CSX)

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 2,165 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Regulation of Inducible and Tissue-Specific Gene Expression

1987 • 1,640 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

The structure and function of the homeodomain

1989 • 1,007 citations

A simple phase-extraction assay for chloramphenicol acyltransferase activity

1988 • 1,006 citations

The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain

1991 • 882 citations

Cystic fibrosis: molecular biology and therapeutic implications

1992 • 820 citations

The gene tinman is required for specification of the heart and visceral muscles in Drosophila

1993 • 790 citations

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

1990 • 545 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

An Escherichia coli vector to express and purify foreign proteins by fusion to and separation from maltose-binding protein

1988 • 539 citations

The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis.

1994 • 518 citations

Drosophila NK-homeobox genes.

1989 • 300 citations

Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain

1992 • 291 citations

Identification of Novel DNA Binding Targets and Regulatory Domains of a Murine Tinman Homeodomain Factor, nkx-2.5

1995 • 289 citations

Lung Cell-specific Expression of the Murine Surfactant Protein A (SP-A) Gene Is Mediated by Interactions between the SP-A Promoter and Thyroid Transcription Factor-1

1995 • 277 citations

A novel B cell-derived coactivator potentiates the activation of immunoglobulin promoters by octamer-binding transcription factors

1992 • 272 citations

Features of embryonic induction

1988 • 271 citations

A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila

1990 • 237 citations

Cell-Type-Specific Expression of the Rat Thyroperoxidase Promoter Indicates Common Mechanisms for Thyroid-Specific Gene Expression

1992 • 210 citations

Variable Effects of Phosphorylation of Pit-1 Dictated by the DNA Response Elements

1991 • 206 citations

[73] Interaction of protein with DNA in vitro

1987 • 203 citations

Gene Structure and Expression of Human Thyroid Transcription Factor-1 in Respiratory Epithelial Cells

1995 • 200 citations

cis-acting elements that confer lung epithelial cell expression of the CC10 gene.

1992 • 144 citations

Three levels of functional interaction determine the activity of CCAAT/enhancer binding protein-alpha on the serum albumin promoter.

1994 • 138 citations

A ubiquitous factor is required for C/EBP-related proteins to form stable transcription complexes on an albumin promoter segment in vitro.

1992 • 138 citations

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

1991 • 133 citations

The lung-specific CC10 gene is regulated by transcription factors from the AP-1, octamer, and hepatocyte nuclear factor 3 families.

1993 • 126 citations

The nucleotide sequences recognized by the glucocorticoid receptor in the rabbit uteroglobin gene region are located far upstream from the initiation of transcription.

1984 • 125 citations

Cystic ibrosis: Molecular Biology and Therapeutic Implications

1992 • 118 citations

Cells of the lung: biology and clinical implications.

1983 • 112 citations

A cell type specific factor recognizes the rat thyroglobulin promoter

1987 • 105 citations

An immunologic study of the secretory products of rat Clara cells.

1984 • 103 citations

The pathology of lung cancer--changing concepts and newer diagnostic techniques.

1988 • 102 citations

Drosophila tissue-specific transcription factor NTF-1 contains a novel isoleucine-rich activation motif.

1993 • 101 citations

Tissue-specific expression, hormonal regulation and 5′-flanking gene region of the rat Clara cell 10 kDa protein: Comparison to rabbit uteroglobin

1990 • 97 citations

The DNA Binding Activity and the Dimerization Ability of the Thyroid Transcription Factor I Are Redox Regulated

1995 • 80 citations

Transcriptional regulation of liver-specific gene expression

1991 • 75 citations

Reversible inhibition of a thyroid-specific trans-acting factor by Ras.

1991 • 68 citations

Identification of hepatocyte nuclear factor-3 binding sites in the Clara cell secretory protein gene

1993 • 65 citations

The Role of the Nonciliated Bronchiolar Epithelial (Clara) Cell as the Progenitor Cell during Bronchiolar Epithelial Differentiation in the Perinatal Rabbit Lung

1992 • 61 citations

Bronchial mucosal cells.

1979 • 60 citations

Expression of SV40 T antigen under control of rabbit uteroglobin promoter in transgenic mice

1991 • 49 citations

Cloning and Characterization of the Mouse Clara Cell-Specific 10-kDa Protein Gene: Comparison of the 5′-Flanking Region with the Human, Rat, and Rabbit Gene

1993 • 48 citations

Cell-specific expression of a Clara cell secretory protein-human growth hormone gene in the bronchiolar epithelium of transgenic mice.

1992 • 48 citations

Clara cell secretory protein gene expression in bronchiolar epithelium

1992 • 45 citations

cis-Acting Elements Involved in the Regulation of Mouse Clara Cell-specific 10-kDa Protein Gene

1995 • 44 citations

Ultrastructural localization of uteroglobin immunoreactivity in rabbit lung and endometrium, and rat ventral prostate

1985 • 44 citations

Partial purification of a binding protein for polychlorinated biphenyls from rat lung cytosol: physicochemical and immunochemical characterization

1988 • 42 citations

Immunohistochemical localization of mouse Clara cell 10-KD protein using antibodies raised against the recombinant protein.

1996 • 37 citations

Cloning and Tissue-specific Expression of the cDNA for the Mouse Clara Cell 10 kD Protein: Comparison of Endogenous Expression to Rabbit Uteroglobin Promoter-driven Transgene Expression

1993 • 30 citations

Expression and Regulation of the Rabbit Uteroglobin Gene in Transgenic Mice

1991 • 29 citations

5' flanking region of the Clara cell secretory protein gene specifies a unique temporal and spatial pattern of gene expression in the developing pulmonary epithelium.

1994 • 15 citations