Imipramine distribution among red blood cells, plasma and brain tissue.

Phosphorus Assay in Column Chromatography

1959 • 12,895 citations

Reevaluating equilibrium and kinetic binding parameters for lipophilic drugs based on a structural model for drug interactions with biological membranes

1991 • 194 citations

G proteins: implications for psychiatry

1992 • 172 citations

Tricyclic Antidepressant Concentrations in Plasma

1994 • 134 citations

Clinical and biochemical aspects of depressive disorders: II. Transmitter/receptor theories

1991 • 124 citations

Binding of some antidepressants to the 5-hydroxytryptamine transporter in brain and platelets

1990 • 96 citations

Plasma levels of tricyclic antidepressants and clinical efficacy: review of the literature -- part II.

1979 • 92 citations

Drug Membrane Interaction and the Importance for Drug Transport, Distribution, Accumulation, Efficacy and Resistance

1994 • 86 citations

Blood and brain concentrations of imipramine, clomipramine and their monomethylated metabolites after oral and intramuscular administration in rats

1977 • 78 citations

Advances in sodium-ion coupled biogenic amine transporters

1992 • 65 citations

The Second-Messenger Dysbalance Hypothesis of Affective Disorders

1990 • 45 citations

Organspecific, qualitative changes in the phospholipid composition of rats after chronic administration of the antidepressant drug desipramine

1988 • 34 citations

Pharmacokinetics of Maprotiline and Its Demethylated Metabolite in Serum and Specific Brain Regions of Rats after Acute and Chronic Administration of Maprotiline

1991 • 30 citations

Plasma and erythrocyte levels of tricyclic antidepressants in depressed patients

1978 • 29 citations

Single and multiple desipramine exposures of cultured cells

1990 • 27 citations

Direct activation of purified Go-type GTP binding protein by tricyclic antidepressants

1992 • 21 citations

Differential Scanning Calorimetry Study of the Interaction of Antidepressant Drugs, Noradrenaline, and 5-Hydroxytryptamine with a Membrane Model

1990 • 20 citations

The route of administration of imipramine as a factor affecting formation of its metabolite desipramine

1982 • 17 citations

Studies on plasma level/effect relationships in imipramine therapy.

1978 • 16 citations

The mechanism of action of antidepressants revised

1990 • 14 citations

On the role of plasma level monitoring of tricyclic antidepressants in clinical practice.

1978 • 13 citations

Serotonin Transport in Reconstituted Endothelial Cell Plasma Membrane Proteoliposomes: Effect of Hypoxia

1992 • 12 citations

Perspectives on Intracellular Storage and Transport of Cationic-Lipophilic Drugs

1993 • 9 citations

Antidepressant plasma levels revisited

1994 • 8 citations

Liposomes - Model Membranes to Study the Binding of Tricyclic Antidepressants

1991 • 7 citations

Radioimmunoassay of Dibenzazepines and Dibenzcycloheptanodienes in Body Fluids and Tissues

1991 • 6 citations

Methylated and Demethylated Tricyclic Antidepressants and Their Binding to Cell Membranes

1991 • 5 citations

Regional distribution and elimination kinetics of imipramine in rat brain after multiple dosages.

1986 • 3 citations

Plasma levels of antidepressants after their withdrawal.

1990 • 2 citations