Electrophysiological and Beta-Receptor Blocking Effects of MJ 1999 on Dog and Rabbit Cardiac Tissue

The effect of the cardiac membrane potential on the rapid availability of the sodium‐carrying system

1955 • 763 citations

On dynamic equilibrium in the heart

1913 • 732 citations

The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibres

1968 • 488 citations

A theory of drug action based on the rate of drug-receptor combination

1961 • 430 citations

Inotropic Effects of Electric Currents

1969 • 305 citations

Effect of lidocaine on the electrophysiological properties of ventricular muscle and Purkinje fibers

1970 • 269 citations

Effects of adrenaline on membrane inward currents during the cardiac action potential

1969 • 267 citations

Pharmacological and toxicological properties of two new beta-adrenergic receptor antagonists.

1965 • 208 citations

Drug antagonism and pAx.

1957 • 207 citations

EVALUATION OF THE CARDIAC EFFECTS OF SEVERAL BETA ADRENERGIC BLOCKING AGENTS

1967 • 205 citations

Electrophysiological Effects of Diphenylhydantoin on Canine Purkinje Fibers

1968 • 204 citations

DIRECTIONAL DIFFERENCES IN THE CONDUCTION OF THE IMPULSE THROUGH HEART MUSCLE AND THEIR POSSIBLE RELATION TO EXTRASYSTOLIC AND FIBRILLARY CONTRACTIONS

1928 • 203 citations

The use of beta-adrenergic receptor blocking drugs in dysrhythmias

1969 • 174 citations

Prevention of ventricular fibrillation induced by coronary ligation.

1968 • 173 citations

APPRAISAL OF THE EFFECTS OF CATECHOLAMINES ON CARDIAC ELECTRICAL ACTIVITY*

1967 • 149 citations

Comparative myocardial depressant and anti-arrhythmic properties of d-propranolol, dl-propranolol and quinidine.

1967 • 125 citations

THE EFFECTS OF PRONETHALOL AND ITS DEXTRO ISOMER UPON EXPERIMENTAL CARDIAC ARRHYTHMIAS.

1965 • 118 citations

Slow inactivation of currents in cardiac Purkinje fibres

1968 • 115 citations

A comparison of the antiarrhythmic actions of two new synthetic compounds, iproveratril and MJ 1999, with quinidine and pronethalol.

1967 • 96 citations

The effect of aconitine on the membrane current in cardiac muscle

1967 • 93 citations

The genesis of cardiac arrhythmias

1966 • 93 citations

Myocardial and local anesthetic actions of β-adrenergic receptor blocking drugs: Relationship to physicochemical properties

1968 • 74 citations

Temporal Relation Between Long-Lasting Aftercontractions and Action Potentials in Cat Papillary Muscles

1968 • 73 citations

Inotropie and Chronotropic Effects of a Series of -Adrenergic Blocking Drugs: Some Structure-Activity Relationships.

1966 • 72 citations

Introductory address. Part I. Biological aspects: the antagonism of drugs

1943 • 63 citations

Antagonism of epinephrine-induced cardiac arrhythmias by 4-(2-isopropylamino-1-hydroxyethyl)-methanesulfonanilide (MJ 1999) .

1966 • 57 citations

Inotropic and metabolic effects of three beta-adrenergic receptor blocking drugs on isolated rabbit left atria.

1965 • 55 citations

Steric aspects of adrenergic drugs. 8. Optical isomers of beta adrenergic receptor antagonists.

1968 • 52 citations

Increase in PNa and PK of Cultured Heart Cells Produced by Veratridine

1969 • 52 citations

Cardiovascular pharmacology of two new beta-adrenergic receptor antagonists.

1965 • 46 citations

A comparative study of some cardiovascular effects of sotalol (MJ 1999) and propranolol

1969 • 45 citations

Antiarrhythmic activity of the dextro- and levorotatory isomers of 4-(2-isopropylamino-1-hydroxyethyl) methanesulfonanilide (MJ 1999).

1968 • 44 citations

Sotalol: A new, safe beta adrenergic receptor blocking agent∗

1968 • 42 citations

Inhibition of cardiac chronotropic action of isoproterenol by Sotalol (MJ 1999) in rat, dog and man.

1967 • 38 citations

Blockade of epinephrine- and ouabain-induced cardiac arrhythmias in the dog heart-lung preparation.

1966 • 35 citations

Beta-adrenergic blocking agents for the treatment of angina pectoris

1969 • 31 citations

The antiarrhythmic properties of ICI 46037, a quaternary analog of propranolol.

1968 • 17 citations

Effects on Myocardial Contractility, Hemodynamics and Cardiac Metabolism of a New Beta-Adrenergic Blocking Drug, Sotalol

1969 • 17 citations

The Myocardial Cell

1966 • 14 citations

Influence of 4-(2-isopropylamino-1-hydroxyethyl) methanesulfonanilide (MJ 1999) on ventricular fibrillation induced by coronary occlusion.

1966 • 3 citations