Beta-adrenergic blocking agents for the treatment of angina pectoris

Hemodynamic Determinants of Oxygen Consumption of the Heart With Special Reference to the Tension-Time Index

1957 • 1,328 citations

Coronary heart disease

1966 • 1,258 citations

Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow

1963 • 1,015 citations

Relation of Heart Rate and Systolic Blood Pressure to the Onset of Pain in Angina Pectoris

1967 • 563 citations

Effects of beta-adrenergic blockade on the cardiac response to maximal and submaximal exercise in man.

1965 • 483 citations

Metabolism of the human heart

1954 • 440 citations

Regulation of Coronary Blood Flow

1991 • 414 citations

Use of Propranolol (Inderal) in Treatment of Hypertension

1964 • 407 citations

Regulation of Coronary Blood Flow

1964 • 383 citations

Control of Coronary Blood Flow by an Autoregulatory Mechanism

1964 • 374 citations

Coronary Circulation in Health and Disease.

1950 • 358 citations

Velocity of contraction as a determinant of myocardial oxygen consumption

1965 • 328 citations

EFFECT OF A β-ADRENERGIC-BLOCKING AGENT, PROPRANOLOL, ON ASTHMATICS

1964 • 309 citations

Unwanted effects of propranolol

1966 • 300 citations

Effect of Coronary Vasodilator Drugs on Retrograde Flow in Areas of Chronic Myocardial Ischemia

1964 • 292 citations

Effect of Nitroglycerin on the Coronary Circulation in Patients with Coronary Artery Disease or Increased Left Ventricular Work

1959 • 291 citations

Hospitals in Switzerland.

1948 • 274 citations

The Relation of Cardiac Effort to Myocardial Oxygen Consumption and Coronary Flow

1958 • 260 citations

Cardiovascular Effects of Glucagon in Man

1968 • 238 citations

Hemodynamic Determinants of Coronary Flow: Effect of Changes in Aortic Pressure and Cardiac Output on the Relationship Between Myocardial Oxygen Consumption and Coronary Flow

1957 • 238 citations

Effects of exercise on myocardial force-velocity relations in intact unanesthetized man: relative roles of changes in heart rate, sympathetic activity, and ventricular dimensions.

1965 • 231 citations

Studies on the pharmacology of glucagon.

1960 • 226 citations

Sympathetic Control of Coronary Circulation

1967 • 213 citations

Measurement of the Angina Threshold Using Atrial Pacing: A New Technique for the Study of Angina Pectoris

1967 • 206 citations

EVALUATION OF THE CARDIAC EFFECTS OF SEVERAL BETA ADRENERGIC BLOCKING AGENTS

1967 • 205 citations

Bronchial Response to Beta-Adrenergic Blockade

1966 • 205 citations

Isoproterenol and cardiovascular performance

1964 • 204 citations

Left Ventricular Pressure -Volume Relationships and Myocardial Oxygen Consumption in the Isolated Heart

1961 • 201 citations

The anginal syndrome with normal coronary arteriography.

1967 • 196 citations

Amelioration of Angina Pectoris in Idiopathic Hypertrophic Subaortic Stenosis with Beta-Adrenergic Blockade

1967 • 192 citations

Metabolic studies on the human heart in vivo

1953 • 192 citations

CARDIAC OXYGEN METABOLISM AND CONTROL OF THE CORONARY CIRCULATION

1947 • 183 citations

The prophylactic value of propranolol in angina pectoris

1966 • 180 citations

Propranolol and angina pectoris

1966 • 178 citations

EFFECTS OF PROPRANOLOL ON THE HORMONAL AND METABOLIC RESPONSES TO INSULIN-INDUCED HYPOGLYCÆMIA

1966 • 176 citations

Effect of propranolol on ventilatory function

1966 • 176 citations

Beta-Adrenergic Receptor Blocking Drugs

1966 • 173 citations

Coronary Circulation in Health and Disease

1951 • 166 citations

Use of Propranolol in Angina Pectoris

1965 • 165 citations

Action of Nitroglycerin on the Coronary Circulation in Normal and in Mild Cardiac Subjects

1959 • 164 citations

CLINICAL PHARMACOLOGY OF A BETA-ADRENERGIC-BLOCKING AGENT (NETHALIDE)

1962 • 163 citations

THE CORONARY CIRCULATION

1946 • 159 citations

Interrelation Between Cardiac Oxygen Consumption and Coronary Blood Flow

1955 • 152 citations

Effect of Left Ventricular Hypertension, Ischemia and Vasoactive Drugs on the Myocardial Distribution of Coronary Flow

1967 • 151 citations

HYPOGLYCÆMIA PRECIPITATED BY PROPRANOLOL

1966 • 149 citations

Propranolol in hypertension

1966 • 147 citations

Effect of Epinephrine and Norepinephrine on Coronary Circulation

1958 • 144 citations

Multicenter trial of propranolol in angina pectoris

1966 • 143 citations

PATTERNS OF HUMAN MYOCARDIAL OXYGEN EXTRACTION DURING REST AND EXERCISE*

1962 • 132 citations

Mechanisms of Angina in Aortic Stenosis

1967 • 131 citations

The Effect of Beta Adrenergic Blockade on Patterns of Urinary Sodium Excretion

1966 • 127 citations

Hemodynamic changes after beta adrenergic blockade

1966 • 125 citations

Adrenergic Receptor Activity in the Coronary Arteries of the Unanesthetized Dog

1967 • 124 citations

Hypoxemia and Coronary Blood Flow12

1957 • 118 citations

Effect of Pronethalol in Angina Pectoris

1963 • 113 citations

Propranolol in Patients with Angina Pectoris

1967 • 111 citations

Effect of Propranolol (Inderal) in Angina Pectoris: Preliminary Report

1964 • 107 citations

Propranolol in the therapy of angina pectoris

1966 • 107 citations

Myocardial metabolism in cardiac hypoxia

1967 • 106 citations

Propranolol and isosorbide dinitrate synergism in angina pectoris

1968 • 105 citations

A Comparative Study of Nitroglycerin and Propranolol

1967 • 104 citations

Double-blind Trail to Propranolol (Inderal) in Angina Pectoris

1965 • 103 citations

An Intrinsic Adrenergic Vasodilator Mechanism in the Coronary Vascular Bed of the Dog

1965 • 98 citations

Effects of beta adrenergic blockade on heart size

1966 • 94 citations

Anaerobic myocardial metabolism

1962 • 87 citations

Double-blind Trial of Propranolol (Inderal) in Angina of Effort

1964 • 86 citations

MYOCARDIAL VASCULAR REACTIVITY AFTER BETA-ADRENERGIC BLOCKADE

1966 • 82 citations

Effects of propranolol on exercise tolerance in angina pectoris

1966 • 80 citations

Beta adrenergic blockade

1968 • 76 citations

Control of the Splanchnic Circulation in Man

1967 • 74 citations

Effects of Beta-Adrenergic Blockade (Propranolol) on Left Ventricular Hemodynamics and the Electrocardiogram During Exercise-Induced Angina Pectoris

1968 • 72 citations

Inotropie and Chronotropic Effects of a Series of -Adrenergic Blocking Drugs: Some Structure-Activity Relationships.

1966 • 72 citations

The pharmacology of beta sympathetic blockade

1966 • 70 citations

Determinants of coronary flow and myocardial oxygen consumption

1962 • 66 citations

Pharmacology of the Coronary Circulation

1965 • 66 citations

Oxidation Reduction in Heart Muscle

1962 • 65 citations

Effect of Propranolol on Systemic and Coronary Hemodynamics at Rest and during Simulated Exercise

1966 • 65 citations

Cardiac output after beta-adrenergic blockade in ischaemic heart disease.

1965 • 64 citations

SEX RATIO IN PHENYLKETONURIA

1970 • 63 citations

Regulation of Coronary Flow

1955 • 62 citations

THE CARDIAC RESPONSE TO STIMULATION OF THE STELLATE GANGLIA AND CARDIAC NERVES

1945 • 61 citations

OBSERVATIONS ON THE MECHANISMS OF INFARCTION IN THE DOG AFTER EXPERIMENTAL OCCLUSION OF THE CORONARY ARTERY

1966 • 61 citations

Physiological Differences between the Effects of Neuronally Released and Bloodborne Norepinephrine on Beta Adrenergic Receptors in the Arterial Bed of the Dog

1967 • 59 citations

THE HAeMODYNAMIC EFFECTS OF -SYMPATHETIC BLOCKADE

1964 • 56 citations

Myocardial Oxygen Consumption and Coronary Blood Flow during Potassium‐Induced Cardiac Arrest and during Ventricular Fibrillation¹

1957 • 55 citations

Inotropic and metabolic effects of three beta-adrenergic receptor blocking drugs on isolated rabbit left atria.

1965 • 55 citations

Effects of interrupted coronary flow upon myocardial metabolism and contractility

1968 • 54 citations

Effects of Propranolol and Its Stereoisomers upon Coronary Vascular Resistance

1967 • 52 citations

The high permeability of human red cells to adenine and hypoxanthine and their ribosides

1960 • 48 citations

BLOCKADE OF SYMPATHETIC β‐RECEPTORS IN THE MYOCARDIAL CIRCULATION

1965 • 47 citations

Influence of norepinephrine on myocardial oxygen consumption under controlled hemodynamic conditions

1965 • 47 citations

Propranolol in hypertension

1966 • 46 citations

Separation of cardioaccelerator and coronary vasomotor fibers in the dog

1961 • 45 citations

Hemodynamic studies and clinical experience with nethalide, a beta-adrenergic blocking agent

1965 • 44 citations

The Effect of a β-Adrenergic-Blocking Agent (Nethalide) and Nitroglycerin on Exercise Tolerance in Angina Pectoris

1965 • 40 citations

Systemic circulatory response to stress of simulated flight and to physical exercise before and after propranolol blockade.

1967 • 40 citations

Propranolol Hydrochloride in the Treatment of Angina Pectoris

1966 • 39 citations

Effects of Norepinephrine on the Coronary Circulation in Man

1964 • 38 citations

Myocardial uptake of free fatty acids and carbohydrates after beta adrenergic blockade

1968 • 35 citations

Beta-Adrenergic Receptor Blocking Drugs

1966 • 34 citations

PROPRANOLOL AND HYPOGLYCEMIA

1967 • 30 citations

Effect of propranolol (inderal) on exercise tolerance in angina pectoris.

1966 • 28 citations

Myocardial Blood Flow in Man Measured by a Coincidence Counting System and a Single Bolus of ⁸⁴ Ribidium Chloride

1968 • 28 citations

Effect of Propranolol on the Peripheral Circulation.

1965 • 26 citations

Effects of Propranolol on Patients with Complete Heart Block and Implanted Pacemakers

1967 • 25 citations

Early Changes in Collateral Flow Following Coronary Artery Ligation: The Role of the Sympathetic Nervous System

1968 • 25 citations

Effect of Therapy on Survival in Angina Pectoris.

1968 • 23 citations

Propranolol and Angina Pectoris

1967 • 22 citations

Beta-adrenergic blockade in cardiac infarction

1968 • 21 citations

DRUG INHIBITION OF CATECHOLAMINE‐INDUCED METABOLIC EFFECTS IN HUMANS*

1967 • 20 citations

THE PHYSIOLOGICAL RÔLE OF CORONARY CONSTRICTOR FIBRES. II. THE RÔLE OF CORONARY VASOMOTORS IN METABOLIC ADAPTATION OF THE CORONARIES

1963 • 20 citations

Modification of cardiovascular responses by propranolol.

1967 • 19 citations

Coronary insufficiency in man

1962 • 19 citations

Systemic lupus erythematosus and pregnancy.

1965 • 18 citations

Effects of iproveratril and nitroglycerin in the heart and coronary circulation of dogs

1968 • 18 citations

Pharmacological Studies with Propranolol (Inderal)

1966 • 18 citations

THE PHYSIOLOGICAL RÔLE OF THE CORONARY CONSTRICTOR FIBRES. I. THE EFFECT OF THE CORONARY VASOMOTORS ON THE SYSTEMIC BLOOD PRESSURE

1963 • 18 citations

CLINICAL EFFICACY OF PROPRANOLOL AS A LOCAL ANAESTHETIC

1967 • 15 citations

Histochemical and electron microscopic study of heart muscle after beta-adrenergic blockade

1967 • 14 citations

Hemodynamic responses to beta-adrenergic blockade in dogs

1967 • 14 citations

The Haemodynamic Effects of Beta-Adrenergic Blockade in Man

1966 • 14 citations

A NEURAL ACTION OF PRONETHALOL*

1967 • 13 citations

Phasic myocardial blood flow in hemorrhagic hypotension

1968 • 12 citations

PROPRANOLOL AND HYPOGLYCÆMIA

1967 • 12 citations

The Effect of Propranolol (‘Inderal’) on Effort Tolerance in Angina Pectoris

1966 • 10 citations

The Pharmacology of the Coronary Circulation

1957 • 10 citations

Beta-Adrenergic Blocking Effects of Propranolol.

1966 • 8 citations

BETA-RECEPTORS IN CORONARY VESSELS

1966 • 8 citations

Nonspecific and beta-adrenergic blocking effects of Alderlin in angina pectoris

1965 • 8 citations

Propranolol in Parkinsonian tremor

1966 • 6 citations

Formation of a New Socket for an Artificial Eye

1894 • 5 citations

The Treatment of Angina Pectoris by Propranolol (‘Inderal’)

1966 • 4 citations