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Colchicine and its analogues: Recent findings

Data up to Jan 2025

Published1988
Citations152
References48

Total Citations Per Year

Abstract

References (48)

The relationship between proton-proton NMR coupling constants and substituent electronegativities—I

1980 • 2,006 citations

A Controlled Trial of Colchicine in Preventing Attacks of Familial Mediterranean Fever

1974 • 414 citations

Isolation, Structure, and Synthesis of Combretastatins A-1 and B-1, Potent New Inhibitors of Microtubule Assembly, Derived from Combretum caffrum

1987 • 312 citations

Microtubules

1978 • 289 citations

Colchicine plasma levels

1970 • 166 citations

Molecular features of colchicine associated with antimitotic activity and inhibition of tubulin polymerization

1976 • 141 citations

Conformational states of tubulin liganded to colchicine, tropolone methyl ether, and podophyllotoxin

1982 • 137 citations

COLCHICINE-BINDING PROTEIN AND THE SECRETION OF THYROID HORMONE

1972 • 117 citations

Synthese des Colchicins

1961 • 111 citations

Interaction of some colchicine analogs, vinblastine and podophyllotoxin with rat brain microtubule protein

1973 • 99 citations

Binding to tubulin of the colchicine analog 2-methoxy-5-(2', 3', 4'-trimethoxyphenyl)tropone. Thermodynamic and kinetic aspects.

1984 • 95 citations

Changes in the circular dichroic spectrum of colchicine associated with its binding to tubulin

1981 • 91 citations

Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines

1981 • 90 citations

Interactions of combretastatin, a new plant-derived antimitotic agent, with tubulin

1983 • 82 citations

Textbook of Rheumatology

1985 • 81 citations

B ring regulation of colchicine binding kinetics and fluorescence.

1986 • 53 citations

Synthesis and biological effects of novel thiocolchicines. 3. evaluation of N-acyldeacetylthiocolchicines, N-(alkoxycarbonyl)deacetylthiocolchicines, and O-ethyldemethylthiocolchicines. New synthesis of thiodemecolcine and antileukemic effects of 2-demethyl- and 3-demethylthiocolchicine

1985 • 49 citations

Stereochemistry of the 1,2,3,4-Dibenzcyclonona-1,3-diene System.1 A Note on the Racemization Barrier in Bridged Biphenyls

1962 • 45 citations

Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines

1983 • 39 citations

Microbial Transformations and 13C-NMR Analysis of Colchicine

1979 • 33 citations

Colchicine binding to antibodies.

1980 • 33 citations

A novel synthesis of colchicide and analogs from thiocolchicine and congeners: reevaluation of colchicide as a potential antitumor agent

1987 • 32 citations

Contraction of the Tropolonic Ring of Colchicine by Hydrogen Peroxide Oxidation

1984 • 25 citations

Herstellung des racemischen Colchicins und des unnatürlichen (+)‐Colchicins

1957 • 24 citations

Facile conversion of natural colchicine into (.+-.)-congeners and (+)-enantiomers including 2-demethyl analogs

1986 • 24 citations

Fluorescein colchicine. Synthesis, purification, and biological activity.

1978 • 24 citations

Simple Conversion of Colchicine into Demecolcine

1979 • 22 citations

The crystal structure of isocolchicine, an inactive isomer of the mitotic spindle inhibitor colchicine

1978 • 22 citations

Alkaloid biosynthesis. Part XVII. The structure and chemistry of androcymbine

1972 • 17 citations

The Microbiological Metabolism of Colchicine

1969 • 16 citations

Synthesis of two aromatic methylenedioxy-substituted colchicine congeners: elucidation of the structure of cornigerine as 2,3-(methylenedioxy)-2,3-didemethoxycolchicine

1981 • 13 citations

Sub-nanogram detection of dihydroartemisinin after chemical derivatization with diacetyldihydrofluorescein followed by high-performance liquid chromatography and UV absorption

1987 • 12 citations

7‐Oxo‐deacetamidocolchiceine and 7‐Benzylimino‐deacetamido‐colchiceine: Two novel products from the base catalysed reaction of (−)‐N‐Benzylidene‐deacetylcolchiceine

1978 • 12 citations

Esters of 1‐O‐Demethylthiocolchicines: Formation of Isomers in Chloroform Solution

1985 • 12 citations

The Structure Elucidation of Pseudothiocolchicine

1985 • 11 citations

Beitrag zur Wirkung des Colchicins

1932 • 11 citations

Selective Ether-cleavage of Thiocolchicoside and Thiocolchine: Characterization of 3- and 2-Demethylthiocolchicine and Catecholic Congeners

1983 • 11 citations

ChemInform Abstract: CONTRACTION OF THE TROPOLONIC RING OF COLCHICINE BY HYDROGEN PEROXIDE OXIDATION

1985 • 10 citations

Detection of Metabolite of Qinghaosu in Nanomolar Quantities: DADF-Esters of Dihydroqinghaosu and Its Epoxy Analog. The Chemistry of Drugs. V

1984 • 10 citations

The structure of colchiceine ethyl acetate–water solvate

1979 • 10 citations

<scp>TETRAMETHOPRIM</scp> and <scp>PENTAMETHOPRIM</scp>: Synthesis, Antibacterial Properties and X‐Ray Structures

1983 • 10 citations

Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congeners

1987 • 9 citations

Revision of the Structure of ‘Epoxycolchicine’

1980 • 9 citations

Reaction of alcohols and amines with diacetyldihydrofluorescein (DADF): Conversion into erythrosine-derivatives on TLC-plates by ammonia and iodine vapors

1984 • 8 citations

Circular Dichroic Spectra and Ionization Processes of Some Tropolonic Alkaloids

1987 • 3 citations

N-Dideuterobutyryldeacetylcolchicine: Probes to Study Colchicine Binding Sites on Tubulin Protein

1985 • 2 citations

Structural studies of colchicine derivatives. III. Structure of 7-deacetamidocolchiceine, C19H20O5

1984 • 1 citations

Structural studies of colchicine derivatives. IV. The structure of colchiceine benzoate monohydrate, C28H27NO7.H2O

1985 • 1 citations

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Colchicine and its analogues: Recent findings (1988) – Medicinal Research Reviews | Metascience Observatory Explorer