Cloning and sequencing a human homolog (hMYH) of the Escherichia coli mutY gene whose function is required for the repair of oxidative DNA damage

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

A short course in bacterial genetics

1992 • 2,245 citations

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

1991 • 2,172 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Mutator phenotype may be required for multistage carcinogenesis.

1991 • 1,327 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

1992 • 875 citations

Splicing of Messenger RNA Precursors

1984 • 874 citations

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.

1995 • 804 citations

Sequence identification of 2,375 human brain genes

1992 • 764 citations

The GO system protects organisms from the mutagenic effect of the spontaneous lesion 8-hydroxyguanine (7,8-dihydro-8-oxoguanine)

1992 • 688 citations

Evidence that MutY and MutM combine to prevent mutations by an oxidatively damaged form of guanine in DNA.

1992 • 590 citations

Microsatellite instability: marker of a mutator phenotype in cancer.

1994 • 552 citations

Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis.

1993 • 437 citations

The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions.

1988 • 343 citations

Characterization of a Mammalian Homolog of the Escherichia coli MutY Mismatch Repair Protein

1995 • 194 citations

mutM, a second mutator locus in Escherichia coli that generates G.C----T.A transversions

1988 • 180 citations

Escherichia coli mutY gene product is required for specific A-G----C.G mismatch correction.

1988 • 152 citations