Effects of tumor promoters on the frequency of metallothionein I gene amplification in cells exposed to cadmium.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.

1978 • 972 citations

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

1982 • 638 citations

Cellular Transforming Genes

1982 • 622 citations

Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene.

1980 • 570 citations

Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.

1979 • 484 citations

Phorbol esters and vasopressin stimulate DNA synthesis by a common mechanism

1980 • 334 citations

Amplification of the metallothionein-I gene in cadmium-resistant mouse cells.

1981 • 314 citations

Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters.

1981 • 254 citations

Isolation and characterization of the mouse metallothionein-I gene.

1980 • 210 citations

Phorbol ester dramatically increases incidence of methotrexate-resistant mouse cells: Possible mechanisms and relevance to tumor promotion

1981 • 171 citations

On the possibility of metabolic control of replicon "misfiring": relationship to emergence of malignant phenotypes in mammalian cell lineages.

1981 • 104 citations

Gene-amplification model of carcinogenesis.

1981 • 86 citations

Toxins, anticancer agents, and tumor promoters from marine prokaryotes

1982 • 75 citations

Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis

1982 • 74 citations

Effects of phorbol ester tumor promoters on arachidonic acid metabolism in chick embryo fibroblasts.

1979 • 64 citations

Do Tumor Promoters Affect DNA After All?

1983 • 53 citations

A new cell line derived from newborn Chinese hamster lung tissue.

1970 • 51 citations

Organization of sequences related to U6 RNA in the human genome

1981 • 50 citations

The third class of new tumor promoters, polyacetates (debromoaplysiatoxin and aplysiatoxin), can differentiate biological actions relevant to tumor promoters.

1982 • 44 citations

Potent tumor promoters other than phorbol ester and their significance.

1982 • 37 citations

Enhancement of cell proliferation in low calcium medium by tumor promoters

1981 • 30 citations

A New Toxic Substance, Teleocidin, Produced byStreptomyces.

1960 • 13 citations