The Glucocorticoid-Induced TNF Receptor-Related Protein (GITR)-GITR Ligand Pathway Acts As a Mediator of Cutaneous Dendritic Cell Migration and Promotes T Cell-Mediated Acquired Immunity

Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche

2004 • 1,387 citations

Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.

1996 • 1,167 citations

CCR7 Governs Skin Dendritic Cell Migration under Inflammatory and Steady-State Conditions

2004 • 997 citations

Langerhans cells renew in the skin throughout life under steady-state conditions

2002 • 946 citations

Dynamics and Function of Langerhans Cells In Vivo

2005 • 899 citations

Early molecular events in the induction phase of contact sensitivity.

1992 • 660 citations

Engagement of Glucocorticoid-Induced TNFR Family-Related Receptor on Effector T Cells by its Ligand Mediates Resistance to Suppression by CD4+CD25+ T Cells

2004 • 498 citations

An essential role for Langerhans cell-derived IL-1 beta in the initiation of primary immune responses in skin.

1993 • 427 citations

Bone Marrow Stromal Cell Antigen 2 Is a Specific Marker of Type I IFN-Producing Cells in the Naive Mouse, but a Promiscuous Cell Surface Antigen following IFN Stimulation

2006 • 423 citations

A new member of the tumor necrosis factor/nerve growth factor receptor family inhibits T cell receptor-induced apoptosis

1997 • 410 citations

Chemokine receptor CCR5 promotes leukocyte trafficking to the brain and survival in West Nile virus infection

2005 • 385 citations

Frontline: GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations

2004 • 358 citations

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

2003 • 353 citations

Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy

2007 • 312 citations

Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells

2004 • 288 citations

Mice deficient in IL-1beta manifest impaired contact hypersensitivity to trinitrochlorobenzone.

1996 • 241 citations

Cutting Edge: The Natural Ligand for Glucocorticoid-Induced TNF Receptor-Related Protein Abrogates Regulatory T Cell Suppression

2004 • 202 citations

Skin Inflammation During Contact Hypersensitivity Is Mediated by Early Recruitment of CD8+ T Cytotoxic 1 Cells Inducing Keratinocyte Apoptosis

2002 • 201 citations

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

1999 • 191 citations

Role of cytokines in epidermal Langerhans cell migration

1999 • 172 citations

Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL)

2006 • 157 citations

Depressed Langerhans cell migration and reduced contact hypersensitivity response in mice lacking TNF receptor p75.

1997 • 152 citations

Migration of Langerhans cells and dermal dendritic cells in skin organ cultures: augmentation by TNF-α and IL-1 β

1999 • 121 citations

Preferential Involvement of Tim-3 in the Regulation of Hepatic CD8+ T Cells in Murine Acute Graft-versus-Host Disease

2006 • 111 citations

Dermal Dendritic Cells, and Not Langerhans Cells, Play an Essential Role in Inducing an Immune Response

2008 • 106 citations

Role of glucocorticoid‐induced TNF receptor family gene (GITR) in collagen‐induced arthritis

2005 • 98 citations

GITR interacts with the pro-apoptotic protein Siva and induces apoptosis

2002 • 98 citations

The differential role of CD86 and CD80 co-stimulatory molecules in the induction and the effector phases of contact hypersensitivity

1996 • 88 citations

Topical Application of Cream-emulsified CD86 siRNA Ameliorates Allergic Skin Disease by Targeting Cutaneous Dendritic Cells

2008 • 81 citations

Expression of CD90 on keratinocyte stem/progenitor cells

2006 • 78 citations

Chemical Activation of Innate and Specific Immunity in Contact Dermatitis

2000 • 73 citations

GITR modulates innate and adaptive mucosal immunity during the development of experimental colitis in mice

2006 • 73 citations

IL-1-induced tumor necrosis factor-alpha elicits inflammatory cell infiltration in the skin by inducing IFN-gamma-inducible protein 10 in the elicitation phase of the contact hypersensitivity response

2003 • 67 citations

Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells

2003 • 65 citations

Proinflammatory Role of Glucocorticoid-Induced TNF Receptor-Related Gene in Acute Lung Inflammation

2006 • 64 citations

NGF-promoted axon growth and target innervation requires GITRL-GITR signaling

2008 • 61 citations

Glucocorticoid-Induced TNF Receptor, a Costimulatory Receptor on Naive and Activated T Cells, Uses TNF Receptor-Associated Factor 2 in a Novel Fashion as an Inhibitor of NF-κB Activation

2005 • 59 citations

Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage

2002 • 53 citations

Cytokine knockouts in contact hypersensitivity research

2003 • 53 citations

GITR ligand-costimulation activates effector and regulatory functions of CD4+ T cells

2008 • 48 citations

Soluble glucocorticoid‐induced tumor necrosis factor receptor (sGITR) increased MMP‐9 activity in murine macrophage

2003 • 44 citations

The existence of CD11c+ sentinel and F4/80+ interstitial dendritic cells in dental pulp and their dynamics and functional properties

2006 • 44 citations

The Glucocorticoid-Induced Tumor Necrosis Factor Receptor-Related Gene Modulates the Response toCandida albicansInfection

2005 • 41 citations

Genetic and pharmacological inhibition of GITR‐GITRL interaction reduces chronic lung injury induced by bleomycin instillation

2006 • 40 citations

Insights into molecular mechanisms of contact hypersensitivity gained from gene knockout studies

2001 • 40 citations

Glucocorticoid-induced TNF receptor family gene (GITR) knockout mice exhibit a resistance to splanchnic artery occlusion (SAO) shock

2004 • 38 citations

Glucocorticoid-induced Tumor Necrosis Factor Receptor Is a p21 Transcriptional Target Conferring Resistance of Keratinocytes to UV Light-induced Apoptosis

2005 • 36 citations

RECOMBINANT GLUCOCORTICOID INDUCED TUMOUR NECROSIS FACTOR RECEPTOR (rGITR) INDUCED COX-2 ACTIVITY IN MURINE MACROPHAGE Raw 264.7 CELLS

2002 • 31 citations

Identification of three distinct subsets of migrating dendritic cells from oral mucosa within the regional lymph nodes

2008 • 30 citations

The Role of CTLA-4 in Murine Contact Hypersensitivity

2001 • 19 citations

Soluble glucocorticoid-induced tumor necrosis factor receptor stimulates osteoclastogenesis by down-regulation of osteoprotegerin in bone marrow stromal cells

2006 • 19 citations