An introduction to PET and SPECT neuroreceptor quantification models.

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

1983 • 3,439 citations

Simplified Reference Tissue Model for PET Receptor Studies

1996 • 1,980 citations

Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data. Generalizations

1985 • 1,604 citations

Distribution Volume Ratios without Blood Sampling from Graphical Analysis of PET Data

1996 • 1,461 citations

Graphical Analysis of Reversible Radioligand Binding from Time—Activity Measurements Applied to [N-¹¹C-Methyl]-(−)-Cocaine PET Studies in Human Subjects

1990 • 1,412 citations

Fitting curves to data using nonlinear regression: a practical and nonmathematical review

1987 • 1,314 citations

Parametric Imaging of Ligand-Receptor Binding in PET Using a Simplified Reference Region Model

1997 • 1,064 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

Kinetic Analysis of Central [¹¹C]Raclopride Binding to D₂-Dopamine Receptors Studied by PET—A Comparison to the Equilibrium Analysis

1989 • 454 citations

Comparison of Bolus and Infusion Methods for Receptor Quantitation: Application to [¹⁸F]Cyclofoxy and Positron Emission Tomography

1993 • 366 citations

[sup 123 I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease

1996 • 363 citations

High‐ and Low‐Affinity Transport of D‐Glucose from Blood to Brain

1981 • 325 citations

Graphical, Kinetic, and Equilibrium Analyses of in vivo [¹²³I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

1994 • 274 citations

PET evaluation of the dopamine system of the human brain.

1996 • 249 citations

Multicompartmental Analysis of [¹¹C]-Carfentanil Binding to Opiate Receptors in Humans Measured by Positron Emission Tomography

1989 • 194 citations

SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil: kinetic and equilibrium paradigms.

1994 • 146 citations

Noninvasive quantification of dopamine D2 receptors with iodine-123-IBF SPECT.

1996 • 131 citations

Requirements and implementation of a flexible kinetic modeling tool.

1997 • 114 citations

SPECT imaging of pre- and postsynaptic dopaminergic alterations in <scp>l</scp> -dopa–untreated PD

1999 • 95 citations

Compartmental modeling of iodine-123-iodobenzofuran binding to dopamine D2 receptors in healthy subjects.

1994 • 90 citations

SPECT Quantification of [¹²³I]Iomazenil Binding to Benzodiazepine Receptors in Nonhuman Primates: I. Kinetic Modeling of Single Bolus Experiments

1994 • 81 citations

Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT.

1999 • 39 citations

In vivo quantification of dopamine D2 receptor parameters in nonhuman primates with [123I]iodobenzofuran and single photon emission computerized tomography

1994 • 36 citations

Modeling of Receptor Ligand Data in PET and SPECT Imaging: A Review of Major Approaches

2001 • 32 citations

Simplified quantification and reproducibility studies of dopamine D2-receptor binding with iodine-123-IBF SPECT in healthy subjects.

1997 • 31 citations