Prognostic relevance of P-glycoprotein expression in breast cancer

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Nonparametric Estimation from Incomplete Observations

1958 • 37,219 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Regression Models and Life-Tables

1972 • 27,145 citations

Evaluation of survival data and two new rank order statistics arising in its consideration.

1966 • 7,595 citations

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

1987 • 2,788 citations

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

1990 • 1,063 citations

Systemic Treatment of Early Breast Cancer by Hormonal, Cytotoxic, or Immune Therapy:133 Randomised Trials involoving 31 000 Recurrences and 24 000 Deaths Among 75 000 Women (Summary)

1993 • 967 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Breast Cancer

1992 • 695 citations

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

1992 • 677 citations

Tumor microvessel density, p53 expression, tumor size, and peritumoral lymphatic vessel invasion are relevant prognostic markers in node-negative breast carcinoma.

1994 • 473 citations

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

1991 • 447 citations

Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies.

1990 • 386 citations

MDR1 Gene Expression and Treatment Outcome in Acute Myeloid Leukemia

1991 • 372 citations

P-glycoprotein expression and function in circulating blood cells from normal volunteers

1994 • 350 citations

Monoclonal antibody JSB‐1 detects a highly conserved epitope on the P‐glycoprotein associated with multi‐drug‐resistance

1988 • 278 citations

Prognostic Factors and Treatment Decisions in Axillary-Node-Negative Breast Cancer

1992 • 277 citations

Prognostic Factors and Therapeutic Decisions in Axillary Node-Negative Breast Cancer

1993 • 265 citations

Relationship of the expression of the multidrug resistance gene product (P-glycoprotein) in human colon carcinoma to local tumor aggressiveness and lymph node metastasis.

1991 • 261 citations

Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues

1990 • 240 citations

Clinical Relevance of Immunohistochemical Detection of Multidrug Resistance P-Glycoprotein in Breast Carcinoma

1991 • 208 citations

Prediction of Doxorubicin Resistance In Vitro in Myeloma, Lymphoma, and Breast Cancer by P-Glycoprotein Staining

1989 • 202 citations

Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line

1991 • 156 citations

Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening.

1992 • 156 citations

P-Glycoprotein expression in treated and untreated human breast cancer

1989 • 133 citations

Patient subsets and variation in therapeutic efficacy.

1982 • 130 citations

Immunohistochemical analysis of P-glycoprotein expression correlated with chemotherapy resistance in locally advanced breast cancer

1990 • 127 citations

Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody.

1993 • 125 citations

The morphometric prognostic index is the strongest prognosticator in premenopausal lymph node-negative and lymph node-positive breast cancer patients

1991 • 99 citations

Optimization of immunocytochemical P-glycoprotein assessment in multidrug-resistant plasma cell myeloma using three antibodies.

1990 • 90 citations

Expression of P-glycoprotein in breast cancer tissue and in vitro resistance to doxorubicin and vincristine

1991 • 86 citations

Expression of mdr1 and gst-π in human breast tumours: comparison to in vitro chemosensitivity

1990 • 86 citations

P-glycoprotein expression in primary breast cancer detected by immunocytochemistry with two monoclonal antibodies

1990 • 85 citations

P-glycoprotein (MDR 1 gene product) in cells of the immune system: Its possible physiologic role and alteration in aging and human immunodeficiency virus-1 (HIV-1) infection

1993 • 76 citations

Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype [see comments]

1991 • 70 citations

Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype [see comments]

1991 • 60 citations

The Multicenter Morphometric Mammary Carcinoma Project (MMMCP)

1989 • 59 citations

P-glycoprotein expression is increased in human secretory and gestational endometrium.

1991 • 56 citations

MDR1 gene expression and prognostic factors in primary breast carcinomas

1991 • 50 citations

Multidrug resistance from the clinical point of view

1991 • 47 citations

Differentiation dependent expression of P-glycoprotein in the normal and neoplastic human kidney

1991 • 37 citations

Tyrosine kinase receptor — nuclear protooncogene interactions in breast cancer

1991 • 20 citations