Refocusing neutralizing antibody response by targeted dampening of an immunodominant epitope.

A general method ofin vitropreparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions

1988 • 2,410 citations

Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody

1994 • 1,106 citations

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

1993 • 1,005 citations

Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.

1990 • 975 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Structural requirements of N-glycosylation of proteins. Studies with proline peptides as conformational probes

1983 • 606 citations

Type-specific neutralization of the human immunodeficiency virus with antibodies to env-encoded synthetic peptides.

1988 • 540 citations

The Acquired Immunodeficiency Syndrome

1983 • 474 citations

Computer-assisted analysis of envelope protein sequences of seven human immunodeficiency virus isolates: prediction of antigenic epitopes in conserved and variable regions

1987 • 443 citations

Characterization of a human immunodeficiency virus neutralizing monoclonal antibody and mapping of the neutralizing epitope

1988 • 412 citations

Complete Nucleotide Sequences of Functional Clones of the AIDS Virus

1987 • 348 citations

Genetic variation in AIDS viruses

1986 • 279 citations

An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection.

1991 • 262 citations

Emergence of viruses resistant to neutralization by V3-specific antibodies in experimental human immunodeficiency virus type 1 IIIB infection of chimpanzees

1990 • 230 citations

Interaction between the human T-cell lymphotropic virus type IIIB envelope glycoprotein gp120 and the surface antigen CD4: role of carbohydrate in binding and cell fusion.

1987 • 220 citations

Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity.

1987 • 219 citations

Antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans

1993 • 208 citations

Identification and characterization of a neutralization site within the second variable region of human immunodeficiency virus type 1 gp120

1992 • 175 citations

Antibody-mediated in vitro neutralization of human immunodeficiency virus type 1 abolishes infectivity for chimpanzees

1990 • 156 citations

Epitopes recognized by the neutralizing antibodies of an HIV-1-infected individual.

1990 • 125 citations

Long-Term High-Titer Neutralizing Activity Induced by Octameric Synthetic HIV-1 Antigen

1991 • 123 citations

Protection of MN-rgp120-Immunized Chimpanzees from Heterologous Infection with a Primary Isolate of Human Immunodeficiency Virus Type 1

1996 • 100 citations

Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1

1995 • 97 citations

Identification of Conserved and Variant Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) gp120 by Human Monoclonal Antibodies Produced by EBV-Transformed Cell Lines

1990 • 79 citations

B Cell Epitope Mapping of Human Immunodeficiency Virus Envelope Glycoproteins with Long (19- to 36-residue) Synthetic Peptides

1990 • 72 citations

B‐Cell Abnormalities in AIDS: Stable and Clonally‐Restricted Antibody Response in HIV‐1 Infection

1993 • 70 citations

Loss of a neutralizing epitope by a spontaneous point mutation in the V3 loop of HIV-1 isolated from an infected laboratory worker.

1993 • 54 citations

Strain specificity and binding affinity requirements of neutralizing monoclonal antibodies to the C4 domain of gp120 from human immunodeficiency virus type 1

1993 • 45 citations

Human Immunodeficiency Virus Glycoproteins: Lectin Binding Properties

1989 • 34 citations

Temporal development of cross-neutralization between HTLV-III B and HTLV-III RF in experimentally infected chimpanzees

1988 • 30 citations

Structural characterization of broadly neutralizing human monoclonal antibodies against the CD4 binding site of HIV-1 gp120

1994 • 29 citations

Frequent and Early HIV-1_MNNeutralizing Capacity in Sera from Dutch HIV-1 Seroconverters Is Related to Antibody Reactivity to Peptides from the gp120 V3 Domain

1994 • 25 citations

Antigen-specific early primary humoral responses modulate immunodominance of B cell epitopes.

1994 • 24 citations

Compositional Similarities between the Human Immunodeficiency Virus and Surface Antigens of Pathogens

1996 • 10 citations

Kernel Density Analysis of Variable and Conserved Regions of the Envelope Proteins of Human Immunodeficiency Virus Type 1 and Associated Epitopes

1996 • 9 citations

Candidate AIDS Vaccine

1987 • 3 citations