Protection of MN-rgp120-Immunized Chimpanzees from Heterologous Infection with a Primary Isolate of Human Immunodeficiency Virus Type 1

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latent viral structure

1990 • 1,560 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

HIV-1 replication is controlled at the level of T cell activation and proviral integration.

1990 • 800 citations

Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

1989 • 781 citations

Conserved Sequence and Structural Elements in the HIV-1 Principal Neutralizing Determinant

1990 • 665 citations

Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160

1990 • 593 citations

Cellular tropism of the human retrovirus HTLV-III/LAV. I. Role of T cell activation and expression of the T4 antigen.

1985 • 545 citations

High concentrations of recombinant soluble CD4 are required to neutralize primary human immunodeficiency virus type 1 isolates.

1990 • 461 citations

Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus.

1991 • 357 citations

Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

1994 • 241 citations

Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses.

1992 • 224 citations

Effect of immunization with a vaccinia-HIV env recombinant on HIV infection of chimpanzees

1987 • 197 citations

Evidence that T cell activation is required for HIV-1 entry in CD4+ lymphocytes.

1989 • 177 citations

Two Antigenically Distinct Subtypes of Human Immunodeficiency Virus Type 1: Viral Genotype Predicts Neutralization Serotype

1994 • 161 citations

Adaptation to persistent growth in the H9 cell line renders a primary isolate of human immunodeficiency virus type 1 sensitive to neutralization by vaccine sera

1995 • 143 citations

Induction of HIV-1-neutralising and syncytium-inhibiting antibodies in uninfected recipients of HIV-1IIIB rgp120 subunit vaccine

1993 • 118 citations

HIV-1 envelope-elicited neutralizing antibody titres correlate with protection and virus load in chimpanzees

1994 • 110 citations

Proliferative and cytotoxic T cells to AIDS virus glycoproteins in chimpanzees immunized with a recombinant vaccinia virus expressing AIDS virus envelope glycoproteins.

1987 • 99 citations

Neutralizing antibodies to HIV-1 in seronegative volunteers immunized with recombinant gp120 from the MN strain of HIV-1. NIAID AIDS Vaccine Clinical Trials Network

1994 • 96 citations

Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1

1992 • 74 citations

Re-evaluation of the Involvement of the Adhesion Molecules ICAM-1/LFA-1 in Syncytia Formation of HIV-1-Infected Subclones of a CEM T-Cell Leukemic Line

1991 • 46 citations