Depression of excitability by sphingosine 1-phosphate in rat ventricular myocytes

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

1993 • 879 citations

Ionic Mechanisms of Propagation in Cardiac Tissue

1997 • 659 citations

Sphingolipids—The Enigmatic Lipid Class: Biochemistry, Physiology, and Pathophysiology

1997 • 640 citations

Conductance properties of single inwardly rectifying potassium channels in ventricular cells from guinea‐pig heart.

1984 • 560 citations

Sphingosine 1-Phosphate, a Bioactive Sphingolipid Abundantly Stored in Platelets, Is a Normal Constituent of Human Plasma and Serum

1997 • 442 citations

Surface:volume relationship in cardiac myocytes studied with confocal microscopy and membrane capacitance measurements: species-dependence and developmental effects

1996 • 322 citations

Sphingosine-1-phosphate rapidly induces Rho-dependent neurite retraction: action through a specific cell surface receptor.

1996 • 280 citations

Sphingosine 1-Phosphate Induces Platelet Activation through an Extracellular Action and Shares a Platelet Surface Receptor with Lysophosphatidic Acid

1997 • 200 citations

Activation of a High Affinity Gi Protein-coupled Plasma Membrane Receptor by Sphingosine-1-phosphate

1996 • 197 citations

Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins.

1996 • 185 citations

Inward Rectification and Implications for Cardiac Excitability

1996 • 168 citations

Role of an inwardly rectifying potassium current in rabbit ventricular action potential.

1992 • 164 citations

Involvement of a Pertussis Toxin-sensitive G Protein in the Mitogenic Signaling Pathways of Sphingosine 1-Phosphate

1995 • 161 citations

The threshold conditions for initiation of action potentials by excitable cells

1966 • 147 citations

Action potentials recorded with patch-clamp amplifiers: are they genuine?

1996 • 136 citations

Cytoskeleton modulates gating of voltage-dependent sodium channel in heart

1995 • 123 citations

Sphingosine 1-phosphate stimulates Rho-mediated tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 fibroblasts

1997 • 112 citations

Activation of muscarinic K+ current in guinea‐pig atrial myocytes by sphingosine‐1‐phosphate.

1995 • 106 citations

Role of sodium‐calcium exchange in activation of contraction in rat ventricle.

1993 • 98 citations

Uncoupling of cardiac cells by fatty acids: structure-activity relationships

1991 • 94 citations

Time-dependent changes in kinetics of Na+ current in single canine cardiac Purkinje cells

1992 • 79 citations

Mechanism of modulation of the voltage-gated skeletal and cardiac muscle sodium channels by fatty acids

1997 • 72 citations

Lysophosphatidic acid inhibits gap-junctional communication and stimulates phosphorylation of connexin-43 in WB cells: possible involvement of the mitogen-activated protein kinase cascade

1994 • 72 citations

Arachidonic acid and lipoxygenase metabolites uncouple neonatal rat cardiac myocyte pairs

1992 • 64 citations

Selected metabolic alterations in the ischemic heart and their contributions to arrhythmogenesis

1994 • 54 citations

Regulation of unloaded cell shortening by sarcolemmal sodium‐calcium exchange in isolated rat ventricular myocytes.

1993 • 53 citations

Sphingolipids as mediators of effects of platelet-derived growth factor in vascular smooth muscle cells

1993 • 51 citations

Characterization of sphingosine 1-phosphate-induced actions and its signaling pathways in rat hepatocytes

1997 • 42 citations

Sphingolipid actions on sodium and calcium currents of rat ventricular myocytes

1996 • 37 citations

Basic Concepts in Cellular Cardiac Electrophysiology: Part I: Ion Channels, Membrane Currents, and the Action Potential

1995 • 32 citations

Sphingosine‐1‐phosphate inhibits extracellular matrix protein‐induced haptotactic motility but not adhesion of B16 mouse melanoma cells

1994 • 28 citations

Dietary n-3 fatty acids in the prevention of lethal cardiac arrhythmias

1997 • 23 citations

Effects of tissue geometry on initiation of a cardiac action potential

1989 • 16 citations

Sphingosine 1-phosphate stimulates Na+/H+ exchange in thyroid FRTL-5 cells

1997 • 15 citations

Characterization of the acetylcholine-sensitive muscarinic K+ channel in isolated feline atrial and ventricular myocytes

1995 • 12 citations