Ionic Mechanisms of Propagation in Cardiac Tissue

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

A practical method for numerical evaluation of solutions of partial differential equations of the heat-conduction type

1947 • 3,041 citations

A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes.

1994 • 1,549 citations

Reconstruction of the action potential of ventricular myocardial fibres

1977 • 1,418 citations

Electric current flow in excitable cells

1976 • 1,353 citations

The heart and cardiovascular system

1986 • 1,333 citations

Cardiac electrophysiology and arrhythmias

1985 • 937 citations

Reentry as a cause of ventricular tachycardia in patients with chronic ischemic heart disease: electrophysiologic and anatomic correlation.

1988 • 764 citations

The electrical constants of a crustacean nerve fibre

1946 • 756 citations

The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents.

1981 • 726 citations

Electrophysiologic and anatomic basis for fractionated electrograms recorded from healed myocardial infarcts.

1985 • 676 citations

The electrical constants of Purkinje fibres

1952 • 628 citations

Inactivation of Ca channels

1984 • 616 citations

Re-entrant ventricular arrhythmias in the late myocardial infarction period. 1. Conduction characteristics in the infarction zone.

1977 • 515 citations

Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts.

1988 • 513 citations

A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation.

1994 • 460 citations

Structural and electrophysiological changes in the epicardial border zone of canine myocardial infarcts during infarct healing.

1985 • 433 citations

Two Components of the Delayed Rectifier K ⁺ Current in Ventricular Myocytes of the Guinea Pig Type

1995 • 417 citations

Electrophysiologic mapping to determine the mechanism of experimental ventricular tachycardia initiated by premature impulses

1982 • 334 citations

Slow recovery from inactivation of inward currents in mammalian myocardial fibres

1974 • 325 citations

Excitatory Factors in Ventricular Tachycardia Resulting from Myocardial Ischemia. Potassium a Major Excitant

1954 • 285 citations

Paradoxical Improvement of Impulse Conduction in Cardiac Tissue by Partial Cellular Uncoupling

1997 • 279 citations

Reentrant ventricular arrhythmias in the late myocardial infarction period. 9. Electrophysiologic-anatomic correlation of reentrant circuits.

1983 • 244 citations

Electrophysiologic Effects of Acute Myocardial Ischemia

1997 • 234 citations

A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue.

1987 • 201 citations

The Stochastic Nature of Cardiac Propagation at a Microscopic Level

1995 • 196 citations

Some electrical and pharmacological properties of gap junctions between adult ventricular myocytes

1985 • 182 citations

Influence of Extracellular K ⁺ Concentration on Cable Properties and Excitability of Sheep Cardiac Purkinje Fibers

1970 • 158 citations

Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes.

1993 • 158 citations

Effects of the discrete pattern of electrical coupling on propagation through an electrical syncytium.

1982 • 156 citations

The Numerical Solution of Ordinary and Partial Differential Equations

1988 • 149 citations

Inhibition and Rapid Recovery of Ca ²⁺ Current During Ca ²⁺ Release From Sarcoplasmic Reticulum in Guinea Pig Ventricular Myocytes

1995 • 145 citations

Anisotropic Activation Spread in Heart Cell Monolayers Assessed by High-Resolution Optical Mapping

1996 • 136 citations

Ca ²⁺ Influx During the Cardiac Action Potential in Guinea Pig Ventricular Myocytes

1996 • 127 citations

Electrical properties of the nexal membrane studied in rat ventricular cell pairs.

1986 • 126 citations

Combined effects of hypoxia, hyperkalemia and acidosis on membrane action potential and excitability of guinea-pig ventricular muscle*

1984 • 121 citations

Directional differences in excitability and margin of safety for propagation in sheep ventricular epicardial muscle.

1990 • 98 citations

Involvement of the Calcium Inward Current in Cardiac Impulse Propagation

1997 • 97 citations

Anisotropic conduction in monolayers of neonatal rat heart cells cultured on collagen substrate.

1994 • 94 citations

Action potential propagation through embryonic dorsal root ganglion cells in culture. I. Influence of the cell morphology on propagation properties

1994 • 86 citations

Propagating depolarization in anisotropic human and canine cardiac muscle: apparent directional differences in membrane capacitance. A simplified model for selective directional effects of modifying the sodium conductance on Vmax, tau foot, and the propagation safety factor.

1987 • 83 citations

Directional characteristics of action potential propagation in cardiac muscle. A model study.

1991 • 77 citations

Modulating L-type calcium current affects discontinuous cardiac action potential conduction

1996 • 68 citations

Effect of resistive discontinuities on waveshape and velocity in a single cardiac fibre

1987 • 63 citations

Control of action potential propagation by intracellular Ca2+ in cultured rat dorsal root ganglion cells.

1996 • 57 citations

Action potential conduction between a ventricular cell model and an isolated ventricular cell

1996 • 49 citations

A Multidimensional Model of Cellular Effects on the Spread of Electrotonic Currents and on Propagating Action Potentials *

2020 • 43 citations

Effects of hypoxia, hyperkalemia, and metabolic acidosis on canine subendocardial action potential conduction.

1987 • 25 citations

Initial Value Ordinary Differential Equations

1988 • 13 citations