Interactions between enteropathogenic Escherichia coli and host epithelial cells

Actin accumulation at sites of bacterial adhesion to tissue culture cells: basis of a new diagnostic test for enteropathogenic and enterohemorrhagic Escherichia coli

1989 • 884 citations

An Inducible Bundle-Forming Pilus of Enteropathogenic Escherichia coli

1991 • 610 citations

Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.

1994 • 594 citations

A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K‐12

1997 • 524 citations

Enteropathogenic Escherichia coli

1992 • 510 citations

Infections of the Gastrointestinal Tract

1996 • 506 citations

Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion

1996 • 451 citations

Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen

1994 • 412 citations

The role of the eae gene of enterohemorrhagic Escherichia coli in intimate attachment in vitro and in a porcine model.

1993 • 365 citations

Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection.

1993 • 345 citations

Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake.

1992 • 328 citations

A plasmid‐encoded type IV fimbrial gene of enteropathogenic Escherichia coli associated with localized adherence

1992 • 288 citations

A plasmid-encoded regulatory region activates chromosomal eaeA expression in enteropathogenic Escherichia coli

1995 • 270 citations

A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation.

1996 • 269 citations

A cluster of fourteen genes from enteropathogenic Escherichia coli is sufficient for the biogenesis of a type IV pilus

1996 • 267 citations

EspA, a protein secreted by enteropathogenic Escherichia coli, is required to induce signals in epithelial cells

1996 • 259 citations

Cell‐surface‐bound Yersinia translocate the protein tyrosine phosphatase YopH by a polarized mechanism into the target cell

1995 • 246 citations

Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cells

1992 • 215 citations

Building bridges: disulphide bond formation in the cell

1994 • 213 citations

The Cell-binding Domain of Intimin from Enteropathogenic Escherichia coli Binds to β1 Integrins

1996 • 199 citations

Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier function

1995 • 187 citations

The bundle‐forming pili of enteropathogenic Escherichia coli: transcriptional regulation by environmental signals

1996 • 177 citations

The eae gene of Citrobacter freundii biotype 4280 is necessary for colonization in transmissible murine colonic hyperplasia

1993 • 175 citations

Elevation of intracellular free calcium levels in HEp-2 cells infected with enteropathogenic Escherichia coli

1991 • 160 citations

Characterization of EspC, a 110-kilodalton protein secreted by enteropathogenic Escherichia coli which is homologous to members of the immunoglobulin A protease-like family of secreted proteins

1996 • 159 citations

Construction and analysis of TnphoA mutants of enteropathogenic Escherichia coli unable to invade HEp-2 cells

1990 • 158 citations

Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophils

1996 • 156 citations

Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers

1993 • 146 citations

DsbA is required for stability of the type IV pilin of enteropathogenic Escherichia coli

1996 • 142 citations

The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells

1994 • 138 citations

Cloning and characterization of bfpTVW, genes required for the transcriptional activation of bfpA in enteropathogenic Escherichia coli

1996 • 137 citations

Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis

1996 • 136 citations

Expression of attaching/effacing activity by enteropathogenic Escherichia coli depends on growth phase, temperature, and protein synthesis upon contact with epithelial cells

1996 • 127 citations

A diarrheal pathogen, enteropathogenic Escherichia coli (EPEC), triggers a flux of inositol phosphates in infected epithelial cells.

1994 • 117 citations

Comparison of Helicobacter pylori and attaching-effacing Escherichia coli adhesion to eukaryotic cells

1993 • 106 citations

Novel form of actin-based motility transports bacteria on the surfaces of infected cells

1996 • 105 citations

Signal transduction responses following adhesion of verocytotoxin-producing Escherichia coli

1995 • 102 citations

Molecular characterization of a carboxy-terminal eukaryotic-cell-binding domain of intimin from enteropathogenic Escherichia coli

1995 • 98 citations

Signal transduction in human epithelial cells infected with attaching and effacing Escherichia coli in vitro

1994 • 77 citations

Intestinal epithelial cell protein phosphorylation in enteropathogenic Escherichia coli diarrhoea

1992 • 73 citations

Protein phosphorylation by protein kinase C in HEp-2 cells infected with enteropathogenic Escherichia coli

1990 • 69 citations

Enteropathogenic Escherichia coli markedly decreases the resting membrane potential of Caco-2 and HeLa human epithelial cells

1996 • 61 citations

Hafnia alvei in stool specimens from patients with diarrhea and healthy controls

1994 • 60 citations

Carbon dioxide regulated secretion of the EaeB protein of enteropathogenicEscherichia coli

1995 • 43 citations