RECEPTOR-G PROTEIN SIGNALING IN YEAST

Molecular Genetics of Human Color Vision: The Genes Encoding Blue, Green, and Red Pigments

1986 • 1,702 citations

Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

1986 • 1,264 citations

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

1986 • 917 citations

Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments.

1986 • 781 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model

1985 • 732 citations

Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.

1986 • 650 citations

A regulatory hierarchy for cell specialization in yeast

1989 • 612 citations

GTP-binding domain: three consensus sequence elements with distinct spacing.

1987 • 602 citations

Genetic and Pharmacological Suppression of Oncogenic Mutations in RAS Genes of Yeast and Humans

1989 • 535 citations

Site of G Protein Binding to Rhodopsin Mapped with Synthetic Peptides from the α Subunit

1988 • 491 citations

Structural basis of β‐adrenergic receptor function

1989 • 480 citations

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.

1987 • 439 citations

G-protein βγ-subunits activate the cardiac muscarinic K+-channel via phospholipase A2

1989 • 438 citations

G proteins control diverse pathways of transmembrane signaling ¹

1989 • 399 citations

Regulation of Adenylyl Cyclase-Coupled beta-Adrenergic Receptors

1988 • 389 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

The yeast α-factor receptor: structural properties deduced from the sequence of theSTE2gene

1985 • 318 citations

The carboxy-terminal segment of the yeast α-factor receptor is a regulatory domain

1988 • 317 citations

Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor.

1986 • 305 citations

cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae

1988 • 270 citations

Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.

1987 • 253 citations

Control of Yeast Mating Signal Transduction by a Mammalian β ₂ -adrenergic Receptor and G _s α Subunit

1990 • 224 citations

The C-terminus of the S. cerevisiae α-pheromone receptor mediates an adaptive response to pheromone

1988 • 214 citations

Binding of α-factor pheromone to yeast a cells: Chemical and genetic evidence for an α-factor receptor

1983 • 211 citations

A yeast operator overlaps an upstream activation site

1987 • 200 citations

Control of yeast cell type by the mating type locus

1981 • 180 citations

Synchronization of haploid yeast cell cycles, a prelude to conjugation

1973 • 174 citations

The STE2 gene product is the ligand-binding component of the alpha-factor receptor of Saccharomyces cerevisiae.

1988 • 174 citations

Protease B of the lysosomelike vacuole of the yeast Saccharomyces cerevisiae is homologous to the subtilisin family of serine proteases.

1987 • 161 citations

G protein linked signal transduction pathways in development: Dictyostelium as an experimental system

1989 • 144 citations

Constitutive mutants in the yeast pheromone response: Ordered function of the gene products

1989 • 143 citations

Common Modifications of Trimeric G Proteins and ras Protein: Involvement of Polyisoprenylation

1990 • 122 citations

Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.

1990 • 118 citations

Regulation of the yeast pheromone response pathway by G protein subunits.

1990 • 116 citations

Morphogenic effects of alpha-factor on Saccharomyces cerevisiae a cells

1976 • 116 citations

Binding of alpha-factor pheromone to Saccharomyces cerevisiae a cells: dissociation constant and number of binding sites.

1986 • 108 citations

Effects of expression of mammalian G alpha and hybrid mammalian-yeast G alpha proteins on the yeast pheromone response signal transduction pathway.

1990 • 108 citations

Induction of the yeast α-specific STE3 gene by the peptide pheromone a-factor

1984 • 97 citations

Multiple regulation of STE2, a mating-type-specific gene of Saccharomyces cerevisiae.

1986 • 88 citations

The Yeast Repeated Element Sigma Contains a Hormone-Inducible Promoter

1987 • 77 citations

An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function.

1988 • 76 citations

GPA1Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae.

1989 • 61 citations

Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae.

1984 • 57 citations

A relationship between the yeast cell cycle genes CDC4 and CDC36 and the ets sequence of oncogenic virus E26

1984 • 51 citations

CDC36 and CDC39 are negative elements in the signal transduction pathway of yeast.

1990 • 41 citations

Mutations Probe Structure and Function of G-protein Chains

1988 • 34 citations

The Yeast G-Protein Homolog Is Involved in the Mating Pheromone Signal Transduction System

1989 • 25 citations

Functional Domains of a Peptide Hormone Receptor: The -Factor Receptor (STE2 Gene Product) of the Yeast Saccharomyces cerevisiae

1988 • 21 citations

Functional Expression of the Yeast α-Factor Receptor in Xenopus Oocytes

1989 • 15 citations

Independent action of α-factor and cycloheximide on the rate of cell-cycle initiation inSaccharomyces cerevisiae

1981 • 7 citations