Vaccination to prevent persistent viral infection

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system

1974 • 2,058 citations

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells

1993 • 1,219 citations

CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection

1994 • 1,161 citations

Molecular mimicry and autoimmune disease

1987 • 943 citations

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.

1984 • 782 citations

Evidence for a differential avidity model of T cell selection in the thymus

1994 • 679 citations

The Virology and Immunobiology of Lymphocytic Choriomeningitis Virus Infection

1980 • 554 citations

Lymphocytic Choriomeningitis Virus

2016 • 423 citations

The Minimal Number of Class II MHC-Antigen Complexes Needed for T Cell Activation

1990 • 410 citations

A Trojan Horse mechanism for the spread of visna virus in monocytes

1985 • 340 citations

How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model

1994 • 309 citations

The Molecular Biology of Human Immunodeficiency Virus Type 1 Infection

1991 • 278 citations

Cytoimitiunotherapy for persistent virus infection reveals a unique clearance pattern from the central nervous system

1986 • 250 citations

Genomic and Biological Variation among Commonly Used Lymphocytic Choriomeningitis Virus Strains

1983 • 241 citations

Immunopathogenesis of HIV infection

1991 • 213 citations

A "string-of-beads" vaccine, comprising linked minigenes, confers protection from lethal-dose virus challenge

1993 • 176 citations

Fine dissection of a nine amino acid glycoprotein epitope, a major determinant recognized by lymphocytic choriomeningitis virus-specific class I-restricted H-2Db cytotoxic T lymphocytes.

1988 • 166 citations

Viruses Perturb Lymphocyte Functions: Selected Principles Characterizing Virus-Induced Immunosuppression

1987 • 152 citations

Molecular anatomy of viral persistence

1991 • 148 citations

Molecular analyses of a five-amino-acid cytotoxic T-lymphocyte (CTL) epitope: an immunodominant region which induces nonreciprocal CTL cross-reactivity

1989 • 138 citations

Vaccination and protection from a lethal viral infection: Identification, incorporation, and use of a cytotoxic T lymphocyte glycoprotein epitope

1990 • 132 citations

Molecularly engineered vaccine which expresses an immunodominant T-cell epitope induces cytotoxic T lymphocytes that confer protection from lethal virus infection

1989 • 127 citations

Virus-lymphocyte interactions IV. Molecular characterization of LCMV Armstrong (CTL+) small genomic segment and that of its variant, clone 13 (CTL−)

1988 • 118 citations

Vaccination for Disease

1991 • 117 citations

Medical Consequences of Persistent Viral Infection

1986 • 99 citations

Antibody-independent activation of the alternative complement pathway by measles virus-infected cells.

1980 • 95 citations

Thymic selection and adaptability of cytotoxic T lymphocyte responses in transgenic mice expressing a viral protein in the thymus.

1994 • 89 citations

The Immune Response to Viruses

1989 • 87 citations

Lysis of measles virus-infected cells by the purified cytolytic alternative complement pathway and antibody.

1979 • 73 citations

Infection of lymphocytes by a virus that aborts cytotoxic T lymphocyte activity and establishes persistent infection.

1991 • 71 citations

Selective disruption of growth hormone transcription machinery by viral infection.

1992 • 58 citations

A common antiviral cytotoxic T-lymphocyte epitope for diverse major histocompatibility complex haplotypes: implications for vaccination.

1992 • 55 citations

Patterns of Persistent Viral Infections

1986 • 50 citations

Diversity of T-cell receptors in virus-specific cytotoxic T lymphocytes recognizing three distinct viral epitopes restricted by a single major histocompatibility complex molecule

1992 • 49 citations

MHC class I and non-MHC-linked capacity for generating an anti-viral CTL response determines susceptibility to CTL exhaustion and establishment of virus persistence in mice.

1994 • 49 citations

Abrogation of tolerance to a chronic viral infection.

1991 • 47 citations

Virus-lymphocyte interactions III. Biologic parameters of a virus variant that fails to generate CTL and establishes persistent infection in immunocompetent hosts

1988 • 41 citations

Failure to cleave measles virus fusion protein in lymphoid cells. A possible mechanism for viral persistence in lymphocytes

1981 • 40 citations

Immunological tolerance to a non-cytopathic virus is not inheritable in mice.

1984 • 3 citations