Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

A PROSPECTIVE, RANDOMIZED TRIAL OF AUTOLOGOUS BONE MARROW TRANSPLANTATION AND CHEMOTHERAPY IN MULTIPLE MYELOMA

2013 • 2,176 citations

Cancer: Principles and Practice of Oncology

1994 • 1,825 citations

Osteopetrosis in mice lacking NF-κB1 and NF-κB2

1997 • 988 citations

Total Therapy With Tandem Transplants for Newly Diagnosed Multiple Myeloma

1999 • 499 citations

Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion

1993 • 437 citations

Maintenance Treatment with Recombinant Interferon Alfa-2b in Patients with Multiple Myeloma Responding to Conventional Induction Chemotherapy

1990 • 389 citations

Primary dexamethasone treatment of multiple myeloma

1992 • 351 citations

Combination chemotherapy versus melphalan and prednisolone in the treatment of multiple myeloma: an overview of published trials.

1992 • 339 citations

VAD‐based regimens as primary treatment for multiple myeloma

1990 • 320 citations

Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell

2000 • 319 citations

Interleukin-6 Inhibits Apoptosis of Malignant Plasma Cells

1995 • 287 citations

Interleukin-6 prevents dexamethasone-induced myeloma cell death

1994 • 275 citations

Interleukin-6 is a potent myeloma-cell growth factor in patients with aggressive multiple myeloma

1989 • 271 citations

High-Dose Glucocorticoid Treatment of Resistant Myeloma

1986 • 251 citations

Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients

2001 • 212 citations

Role of NF-κB in the Rescue of Multiple Myeloma Cells From Glucocorticoid-Induced Apoptosis by Bcl-2

1999 • 202 citations

INFUSION OF VINCRISTINE AND DOXORUBICIN WITH ORAL DEXAMETHASONE AS FIRST-LINE THERAPY FOR MULTIPLE MYELOMA

1989 • 198 citations

Interferon-α treatment in multiple myeloma: Meta-analysis of 30 randomised trials among 3948 patients

2000 • 168 citations

Interleukin-1 accelerates autocrine growth of myeloma cells through interleukin-6 in human myeloma

1989 • 141 citations

Combination chemotherapy, glucocorticoids, and interferon alfa in the treatment of multiple myeloma: a Southwest Oncology Group study.

1994 • 139 citations

Verapamil reversal of doxorubicin resistance in multidrug-resistant human myeloma cells and association with drug accumulation and DNA damage.

1988 • 105 citations

Randomized trial of interferon maintenance in multiple myeloma: a study of the National Cancer Institute of Canada Clinical Trials Group.

1995 • 102 citations

Reversal of drug‐resistance in multiple myeloma with verapamil

1988 • 102 citations

Interferon alfa‐2b versus no maintenance therapy during the plateau phase in multiple myeloma: a randomized study

1995 • 96 citations

Interferon-alpha for induction and maintenance in multiple myeloma: Results of two multicenter randomized trials and summary of other studies

1995 • 90 citations

A comparison of polychemotherapy and melphalan/prednisone for primary remission induction, and interferon-alpha for maintenance treatment, in multiple myeloma. A prospective trial of the German Myeloma Treatment Group

1995 • 75 citations

Effect of glucocorticoids on the biologic activities of myeloma cells: inhibition of interleukin-1 beta osteoclast activating factor-induced bone resorption

1990 • 63 citations

Interferon versus interferon plus prednisone remission maintenance therapy for multiple myeloma: a Southwest Oncology Group Study.

1998 • 62 citations

Remission Maintenance Therapy for Multiple Myeloma

1975 • 62 citations

IFN-alpha is a survival factor for human myeloma cells and reduces dexamethasone-induced apoptosis.

1998 • 60 citations

Enhanced cytotoxicity against colon carcinoma by combinations of noncompeting monoclonal antibodies to the 17-1A antigen.

1988 • 53 citations

IFN-α Is a Survival Factor for Human Myeloma Cells and Reduces Dexamethasone-Induced Apoptosis

1998 • 48 citations

High‐dose dexamethasone for refractory or relapsing multiple myeloma

1991 • 43 citations

Randomized trial of ?-interferon or dexamethasone as maintenance treatment for multiple myeloma

2000 • 39 citations

Response rate and survival in myeloma patients receiving prednisone alone

1985 • 28 citations

Dose Intensity Analysis of Melphalan and Prednisone in Multiple Myeloma

1988 • 23 citations

Interferon plus Glucocorticoids as Intensified Maintenance Therapy Prolongs Tumor Control in Relapsed Myeloma

1993 • 15 citations

Deleted Work

1955 • 0 citations

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