The Saccharomyces cerevisiae RAD9 Checkpoint Reduces the DNA Damage-Associated Stimulation of Directed Translocations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Life with 6000 Genes

1996 • 4,125 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

The distribution of the numbers of mutants in bacterial populations

1949 • 1,471 citations

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1992 • 1,358 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

1992 • 1,117 citations

Loss of a yeast telomere: Arrest, recovery, and chromosome loss

1993 • 787 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

One-step transformation of yeast in stationary phase

1992 • 683 citations

The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control

1976 • 518 citations

Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae.

1992 • 514 citations

Yeast Checkpoint Genes in DNA Damage Processing: Implications for Repair and Arrest

1995 • 418 citations

Functions of microtubules in the Saccharomyces cerevisiae cell cycle.

1988 • 410 citations

Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: the Role of the Yeast Ultraviolet Repair Gene RAD1

1992 • 375 citations

Centromeric DNA from Saccharomyces cerevisiae

1982 • 292 citations

Nucleotide sequence and transcriptional mapping of the yeastpet56-his3-dedlgene region

1985 • 290 citations

Specific Cleavage of Model Recombination and Repair Intermediates by the Yeast Rad1-Rad10 DNA Endonuclease

1994 • 265 citations

Cell cycle arrest of cdc mutants and specificity of the RAD9 checkpoint.

1993 • 263 citations

UV MUTAGENESIS IN RADIATION-SENSITIVE STRAINS OF YEAST

1976 • 255 citations

Lethality induced by a single site-specific double-strand break in a dispensable yeast plasmid.

1993 • 254 citations

High Spontaneous Intrachromosomal Recombination Rates in Ataxia-Telangiectasia

1993 • 240 citations

Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

1988 • 232 citations

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage.

1990 • 223 citations

RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination.

1988 • 209 citations

RAD9, RAD17, and RAD24 Are Required for S Phase Regulation in Saccharomyces cerevisiae in Response to DNA Damage

1997 • 198 citations

RAD9-dependent G1 arrest defines a second checkpoint for damaged DNA in the cell cycle of Saccharomyces cerevisiae.

1993 • 195 citations

Radiosensitivity in Ataxia-telangiectasia: Anomalies in Radiation-induced Cell Cycle Delay

1994 • 192 citations

Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1.

1993 • 178 citations

Physical mapping of large DNA by chromosome fragmentation.

1988 • 170 citations

A 24-base-pair DNA sequence from the MAT locus stimulates intergenic recombination in yeast.

1986 • 169 citations

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1995 • 167 citations

Characterization of G1 checkpoint control in the yeast Saccharomyces cerevisiae following exposure to DNA-damaging agents.

1994 • 148 citations

Multiple pathways for homologous recombination in Saccharomyces cerevisiae.

1995 • 142 citations

Directionality and Regulation of Cassette Substitution in Yeast

1984 • 139 citations

Cloning and sequence analysis of the Saccharomyces cerevisiae RAD9 gene and further evidence that its product is required for cell cycle arrest induced by DNA damage.

1989 • 134 citations

Nonmutagenic carcinogens induce intrachromosomal recombination in yeast

1989 • 134 citations

Cell cycle checkpoints, genetic instability and cancer.

1993 • 126 citations

A defect in mismatch repair in Saccharomyces cerevisiae stimulates ectopic recombination between homeologous genes by an excision repair dependent process.

1990 • 117 citations

A physical, genetic and transcriptional map of the cloned his3 gene region of Saccharomyces cerevisiae

1980 • 116 citations

A novel role for the budding yeast RAD9 checkpoint gene in DNA damage-dependent transcription.

1996 • 111 citations

The Product of the HO Gene Is a Nuclease: Purification and Characterization of the Enzyme

1984 • 105 citations

Recombinational substrates designed to study recombination between unique and repetitive sequences in vivo.

1987 • 104 citations

Lack of association between intrachromosomal gene conversion and reciprocal exchange

1984 • 103 citations

Replication-dependent sister chromatid recombination in rad1 mutants of Saccharomyces cerevisiae.

1993 • 86 citations

The relevance of the nuclear division cycle to radiosensitivity in yeast

1978 • 80 citations

Spontaneous mitotic recombination in yeast: the hyper-recombinational rem1 mutations are alleles of the RAD3 gene.

1988 • 77 citations

GENETIC AND MOLECULAR ANALYSIS OF THE GAL3 GENE IN THE EXPRESSION OF THE GALACTOSE/MELIBIOSE REGULON OF SACCHAROMYCES CEREVISIAE

1986 • 73 citations

Cell-cycle-specific repair of DNA double strand breaks in Saccharomyces cerevisiae.

1980 • 71 citations

Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia

1989 • 69 citations

Gene conversion at different points in the mitotic cycle of Saccharomyces cerevisiae

1984 • 63 citations

On the mechanism of UV and γ-ray-induced intrachromosomal recombination in yeast cells synchronized in different stages of the cell cycle

1995 • 61 citations

Simultaneous detection of changes in chromosome number, gene conversion and intergenic recombination during mitosis of Saccharomyces cerevisiae: spontaneous and ultraviolet light induced events

1982 • 60 citations

RAD1, an Excision Repair Gene of Saccharomyces cerevisiae, Is Also Involved in Recombination

1988 • 60 citations

Cell-Cycle-Specific Repair of DNA Double-Strand Breaks in Saccharomyces cerevisiae

1980 • 57 citations

Characterization of RAD9 of Saccharomyces cerevisiae and Evidence that Its Function Acts Posttranslationally in Cell Cycle Arrest after DNA Damage

1990 • 55 citations

A physical comparison of chromosome III in six strains of Saccharomyces cerevisiae

1994 • 54 citations

Genome rearrangement in top3 mutants of Saccharomyces cerevisiae requires a functional RAD1 excision repair gene.

1992 • 53 citations

Gene conversion and associated reciprocal recombination are separable events in vegetative cells of Saccharomyces cerevisiae.

1983 • 51 citations

Origins of Gene Conversion and Reciprocal Exchange in Ascobolus

1984 • 49 citations

Mitotic recombination: Mismatch correction and replicational resolution of holliday structures formed at the two strand stage in Saccharomyces

1981 • 46 citations

Molecular cloning and characterization of the RAD1 gene of Saccharomyces cerevisiae

1983 • 46 citations

Recombination of Ty elements in yeast can be induced by a double-strand break.

1995 • 45 citations

Direction of chromosome rearrangements in Saccharomyces cerevisiae by use of his3 recombinational substrates.

1988 • 44 citations

Cloning and Sequence Analysis of the Saccharomyces cerevisiae RAD9 Gene and Further Evidence that Its Product Is Required for Cell Cycle Arrest Induced by DNA Damage

1989 • 36 citations

Regulation of the RAD6 gene of Saccharomyces cerevisiae in the mitotic cell cycle and in meiosis

1986 • 35 citations

DNA-damaging agents stimulate the formation of directed reciprocal translocations in Saccharomyces cerevisiae

1994 • 33 citations

Arrest of the mitotic cell cycle and of meiosis in Saccharomyces cerevisiae by MMS

1985 • 33 citations

Mating type regulates the radiation-associated stimulation of reciprocal translocation events in Saccharomyces cerevisiae

1994 • 29 citations

Genome Rearrangement in top3 Mutants of Saccharomyces cerevisiae Requires a Functional RAD1 Excision Repair Gene

1992 • 15 citations

Direction of Chromosome Rearrangements in Saccharomyces cerevisiae by Use of his3 Recombinational Substrates

1988 • 12 citations

Characterization of a B-lymphocyte t(2;14) (p11;q32) translocation from an ataxia telangiectasia patient conferring a proliferative advantage on cells in vitro

1991 • 8 citations