Cloning and Sequence Analysis of the Saccharomyces cerevisiae RAD9 Gene and Further Evidence that Its Product Is Required for Cell Cycle Arrest Induced by DNA Damage

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli

1984 • 1,608 citations

Codon selection in yeast.

1982 • 1,580 citations

The SOS regulatory system of Escherichia coli

1982 • 1,491 citations

Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles

1983 • 1,256 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

The molecular biology of the yeast saccharomyces

1982 • 1,165 citations

Transformation in yeast: Development of a hybrid cloning vector and isolation of the can1 gene

1979 • 1,080 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Replacement of chromosome segments with altered DNA sequences constructed in vitro.

1979 • 779 citations

Methods in yeast genetics, laboratory manual

1987 • 733 citations

The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

1987 • 731 citations

GENETIC CONTROL OF THE CELL DIVISION CYCLE IN YEAST: V. GENETIC ANALYSIS OF cdc MUTANTS

1973 • 728 citations

The making of strand-specific M13 probes

1982 • 652 citations

Isolation of genes by complementation in yeast: molecular cloning of a cell-cycle gene.

1980 • 502 citations

GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast

1985 • 496 citations

An inducible DNA replication–cell division coupling mechanism in E. coli

1981 • 450 citations

A Method for Gene Disruption That Allows Repeated Use of URA3 Selection in the Construction of Multiply Disrupted Yeast Strains

1987 • 408 citations

ALTERED FIDELITY OF MITOTIC CHROMOSOME TRANSMISSION IN CELL CYCLE MUTANTS OF S. CEREVISIAE

1985 • 390 citations

Gene conversion between duplicated genetic elements in yeast

1981 • 353 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

The mitotic inducer nim1+ functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

1987 • 334 citations

GCN4 protein, a positive transcription factor in yeast, binds general control promoters at all 5' TGACTC 3' sequences.

1986 • 320 citations

Lethal Disruption of the Yeast Actin Gene by Integrative DNA Transformation

1982 • 298 citations

Mechanism by which caffeine potentiates lethality of nitrogen mustard.

1982 • 294 citations

Characterization of postreplication repair in Saccharomyces cerevisiae and effects of rad6, rad18, rev3 and rad52 mutations

1981 • 289 citations

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

1987 • 279 citations

Three Additional Genes Required for Deoxyribonucleic Acid Synthesis in Saccharomyces cerevisiae

1973 • 278 citations

Saccharomyces cerevisiae cell cycle mutant cdc9 is defective in DNA ligase

1978 • 260 citations

The DNA-binding domains of the jun oncoprotein and the yeast GCN4 transcriptional activator protein are functionally homologous

1987 • 260 citations

UV MUTAGENESIS IN RADIATION-SENSITIVE STRAINS OF YEAST

1976 • 255 citations

Role of sulA and sulB in filamentation by lon mutants of Escherichia coli K-12

1981 • 229 citations

ISOLATION AND CHARACTERIZATION OF MMS-SENSITIVE MUTANTS OF SACCHAROMYCES CEREVISIAE

1977 • 216 citations

Genetic control of the cell division cycle in yeast

1971 • 214 citations

Regulation of MPF activity in vitro

1988 • 209 citations

Different drugs arrest cells at a number of distinct stages in G2

1975 • 201 citations

The RAD6 protein of Saccharomyces cerevisiae polyubiquitinates histones, and its acidic domain mediates this activity.

1988 • 196 citations

Effects of Caffeine on Radiation-Induced Phenomena Associated with Cell-Cycle Traverse of Mammalian Cells

1974 • 191 citations

Mutagenesis in Saccharomyces Cerevisiae

1982 • 181 citations

Radiation-Sensitive Mutants and Repair in Yeast

1983 • 177 citations

The Action of Caffeine on X-Irradiated HeLa Cells: III. Enhancement of X-Ray-Induced Killing during G 2 Arrest

1978 • 160 citations

Premature chromosome condensation I. Visualization of X-ray-induced chromosome damage in interphase cells

1974 • 154 citations

RAD6 gene of Saccharomyces cerevisiae encodes a protein containing a tract of 13 consecutive aspartates.

1985 • 151 citations

TheSaccharomyces cerevisiae RAD18gene encodes a protein that contains potential zinc finger domains for nucleic acid binding and a putative nucleotide binding sequence

1988 • 147 citations

Fungal recombination

1985 • 121 citations

Analysis of the mechanism for reversion of a disrupted gene.

1988 • 114 citations

Yeast gene CDC8 encodes thymidylate kinase and is complemented by herpes thymidine kinase gene TK.

1984 • 109 citations

The Cause of G2-Arrest in Chinese Hamster Ovary Cells Treated With Anticancer Drugs2

1976 • 104 citations

Nucleotide sequence, transcript mapping, and regulation of the RAD2 gene of Saccharomyces cerevisiae

1986 • 97 citations

The relevance of the nuclear division cycle to radiosensitivity in yeast

1978 • 80 citations

Saccharomyces cerevisiae cdc9, a Structural Gene for Yeast DNA Ligase which Complements Schizosaccharomyces pombe cdc 17

1983 • 64 citations

Changes in protein phosphorylation during the cell cycle of Chinese hamster ovary cells.

1985 • 48 citations

Premature chromosome condensation II. The nature of chromosome gaps produced by alkylating agents and ultraviolet light

1974 • 48 citations

Spontaneous mitotic recombination in mms8-1, an allele of the CDC9 gene of Saccharomyces cerevisiae

1981 • 47 citations

Phosphorylation of non-histone proteins associated with mitosis in HeLa cells

1984 • 45 citations

Isolation and characterization of the RAD2 gene of Saccharomyces cerevisiae

1984 • 39 citations

X-ray enhances mating type switching in heterothallic strains of Saccharomyces cerevisiae

1982 • 36 citations

Arrest of the mitotic cell cycle and of meiosis in Saccharomyces cerevisiae by MMS

1985 • 33 citations

Domain Structure and Functional Analysis of the Carboxyl-Terminal Polyacidic Sequence of the RAD6 Protein of Saccharomyces cerevisiae

1988 • 31 citations

Molecular mechanisms of the chromosome condensation and decondensation cycle in mammalian cells

1986 • 28 citations

a/alpha-specific effect on the mms3 mutation on ultraviolet mutagenesis in Saccharomyces cerevisiae

1981 • 13 citations