Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae

Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation

2000 • 1,939 citations

Translational control in stress and apoptosis

2005 • 1,328 citations

Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies

2003 • 1,323 citations

Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress

2006 • 1,285 citations

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

2006 • 1,006 citations

RNA granules

2006 • 946 citations

The enzymes and control of eukaryotic mRNA turnover

2004 • 793 citations

Movement of Eukaryotic mRNAs Between Polysomes and Cytoplasmic Processing Bodies

2005 • 754 citations

Processing bodies require RNA for assembly and contain nontranslating mRNAs

2005 • 696 citations

A role for the P-body component GW182 in microRNA function

2005 • 670 citations

A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation.

1993 • 660 citations

Cytoplasmic foci are sites of mRNA decay in human cells

2004 • 644 citations

The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex

1998 • 632 citations

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

2005 • 631 citations

General Translational Repression by Activators of mRNA Decapping

2005 • 630 citations

The Transcription Factor Associated Ccr4 and Caf1 Proteins Are Components of the Major Cytoplasmic mRNA Deadenylase in Saccharomyces cerevisiae

2001 • 574 citations

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript.

1994 • 511 citations

Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae.

1990 • 409 citations

Control of mRNA Decay by Heat Shock-Ubiquitin-Proteasome Pathway

1999 • 395 citations

Ccr4p is the catalytic subunit of a Ccr4p/Pop2p/Notp mRNA deadenylase complex inSaccharomyces cerevisiae

2002 • 325 citations

Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs in Saccharomyces cerevisiae

1999 • 240 citations

Mutations affecting stability and deadenylation of the yeast MFA2 transcript.

1992 • 228 citations

The yeast POP2 gene encodes a nuclease involved in mRNA deadenylation

2001 • 196 citations

A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons.

1993 • 192 citations

The Yeast Pan2 Protein Is Required for Poly(A)-binding Protein-stimulated Poly(A)-nuclease Activity

1996 • 182 citations

Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA

1994 • 174 citations

Mutations in trans-Acting Factors Affecting mRNA Decapping in Saccharomyces cerevisiae

1996 • 168 citations

Identification and Comparison of Stable and Unstable mRNAs in Saccharomyces cerevisiae

1990 • 125 citations

Mild temperature shock affects transcription of yeast ribosomal protein genes as well as the stability of their mRNAs

1988 • 85 citations

Glucose starvation induces a drastic reduction in the rates of both transcription and degradation of mRNA in yeast

2000 • 77 citations

Stressed out! Effects of environmental stress on mRNA metabolism

2006 • 75 citations

A Small Segment of the MATα1 Transcript Promotes mRNA Decay in Saccharomyces cerevisiae: a Stimulatory Role for Rare Codons

1993 • 63 citations

Double-stranded RNA-dependent Protein Kinase (pkr) Is Essential for Thermotolerance, Accumulation of HSP70, and Stabilization of ARE-containing HSP70 mRNA during Stress

2002 • 52 citations

Preferential deadenylation of Hsp70 mRNA plays a key role in regulating Hsp70 expression in Drosophila melanogaster.

1994 • 51 citations

Expression of the HXT13, HXT15 and HXT17 genes in Saccharomyces cerevisiae and stabilization of the HXT1 gene transcript by sugar-induced osmotic stress

2006 • 48 citations

Inhibition of mRNA deadenylation and degradation by different types of cell stress

2006 • 45 citations

Inhibition of 5′ to 3′ mRNA degradation under stress conditions in Saccharomyces cerevisiae: from GCN4 to MET16

2004 • 22 citations

Sodium-induced GCN4 Expression Controls the Accumulation of the 5′ to 3′ RNA Degradation Inhibitor, 3′-Phosphoadenosine 5′-Phosphate

2005 • 17 citations

Preferential Deadenylation of Hsp70 mRNA Plays a Key Role in Regulating Hsp70 Expression in Drosophila melanogaster

1994 • 13 citations