The sea urchin multicatalytic protease: purification, biochemical analysis, subcellular distribution, and relationship to snRNPs.

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

1977 • 5,640 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

A rapid, sensitive, and specific method for the determination of protein in dilute solution

1973 • 2,518 citations

Gene Activity in Early Development

1968 • 1,725 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Purification of two high molecular weight proteases from rabbit reticulocyte lysate.

1987 • 542 citations

Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome)

1988 • 404 citations

The Ro small cytoplasmic ribonucleoproteins: identification of the antigenic protein and its binding site on the Ro RNAs.

1984 • 372 citations

The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.

1984 • 371 citations

A high molecular weight protease in the cytosol of rat liver. I. Purification, enzymological properties, and tissue distribution.

1986 • 327 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

The prosome: an ubiquitous morphologically distinct RNP particle associated with repressed mRNPs and containing specific ScRNA and a characteristic set of proteins.

1984 • 180 citations

Drosophila small cytoplasmic 19S ribonucleoprotein is homologous to the rat multicatalytic proteinase

1988 • 179 citations

Purification of the individual snRNPs U1, U2, U5 and U4/U6 from HeLa cells and characterization of their protein constituents.

1986 • 170 citations

Prosomes

1986 • 122 citations

Characterization of the prosome from Drosophila and its similarity to the cytoplasmic structures formed by the low molecular weight heat-shock proteins.

1985 • 110 citations

Eukaryotic pre-tRNA 5′ processing nuclease: Copurification with a complex cylindrical particle

1986 • 106 citations

Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cells.

1986 • 100 citations

Skeletal muscle proteasome can degrade proteins in an ATP-dependent process that does not require ubiquitin.

1989 • 93 citations

THE ISOLATION OF NUCLEI FROM EGGS AND EMBRYOS OF THE SEA URCHIN

1962 • 91 citations

Cytolocalization of prosomes as a function of differentiation

1988 • 73 citations

A 20S particle ubiquitous from yeast to human

1987 • 67 citations

Sea urchin prosome: characterization and changes during development.

1987 • 59 citations

Fertilization triggers unmasking of maternal mRNAs in sea urchin eggs.

1987 • 58 citations

Analysis of changes in a yolk glycoprotein complex in the developing sea urchin embryo

1985 • 53 citations

Structure of the sea urchin U1 RNA repeat

1985 • 53 citations

The 19S ring-type particles of Drosophila

1987 • 46 citations

An assessment of the masked message hypothesis: Sea urchin egg messenger ribonucleoprotein complexes are efficient templates for in vitro protein synthesis

1982 • 41 citations

Transient synthesis of a specific set of proteins during the rapid cleavage phase of sea urchin development

1986 • 39 citations

Differential repression of specific mRNA in erythroblast cytoplasm: a possible role for free mRNP proteins.

1983 • 35 citations

Sea urchin maternal and embryonic U1 RNAs are spatially segregated in early embryos.

1987 • 27 citations

Evidence for an association between U1 RNA and interspersed repeat single-copy RNAs in the cytoplasm of sea urchin eggs†

1987 • 21 citations

19s cylinder particles ubiqutious from plants to man: Their morphology, molecular composition and potential functions

1987 • 17 citations

Fertilization triggers unmasking of maternal mRNAs in sea urchin eggs

1987 • 8 citations