Surgical and Radiosurgical Management of Brain Metastases

A Randomized Trial of Surgery in the Treatment of Single Metastases to the Brain

1990 • 3,068 citations

Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial

2004 • 2,348 citations

Postoperative Radiotherapy in the Treatment of Single Metastases to the Brain

1998 • 1,864 citations

Incidence Proportions of Brain Metastases in Patients Diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System

2004 • 1,678 citations

Prophylactic Cranial Irradiation for Patients with Small-Cell Lung Cancer in Complete Remission

1999 • 1,607 citations

Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma

2002 • 1,520 citations

Central nervous system metastases in women who receive trastuzumab‐based therapy for metastatic breast carcinoma

2003 • 1,284 citations

Treatment of single brain metastasis: Radiotherapy alone or combined with neurosurgery

1993 • 1,034 citations

Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases

1999 • 1,002 citations

The palliation of brain metastases: Final results of the first two studies by the radiation therapy oncology group

1980 • 968 citations

Radiation‐induced dementia in patients cured of brain metastases

1989 • 943 citations

Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors [RETIRED]

2000 • 834 citations

Distribution of Brain Metastases

1988 • 773 citations

A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis

1994 • 706 citations

CNS Metastases in Breast Cancer

2004 • 692 citations

A randomized trial to assess the efficacy of surgery in addition to radiotherapy in patients with a single cerebral metastasis

1996 • 680 citations

The choice of treatment of single brain metastasis should be based on extracranial tumor activity and age

1994 • 649 citations

Surgical treatment of multiple brain metastases

1993 • 560 citations

Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma

1998 • 548 citations

A multi-institutional review of radiosurgery alone vs. radiosurgery with whole brain radiotherapy as the initial management of brain metastases

2002 • 510 citations

Determinants of Outcome in Melanoma Patients With Cerebral Metastases

2004 • 431 citations

Radiosurgery for brain metastases: is whole brain radiotherapy necessary?

1999 • 413 citations

Methylphenidate therapy improves cognition, mood, and function of brain tumor patients.

1998 • 377 citations

Temozolomide for the Treatment of Brain Metastases Associated With Metastatic Melanoma: A Phase II Study

2004 • 352 citations

A comparison of surgical resection and stereotactic radiosurgery in the treatment of solitary brain metastases

2003 • 318 citations

Surgery versus radiosurgery in the treatment of brain metastasis

1996 • 310 citations

Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis

2001 • 282 citations

Radiosurgery for the treatment of previously irradiated recurrent primary brain tumors and brain metastases: Initial report of radiation therapy oncology group protocol 90-05

1996 • 279 citations

Surgery and radiotherapy compared with gamma knife radiosurgery in the treatment of solitary single cerebral metastases of small diameter

1999 • 277 citations

Radiosurgery in patients with renal cell carcinoma metastasis to the brain: long-term outcomes and prognostic factors influencing survival and local tumor control

2003 • 273 citations

Stereotactic radiosurgery for cerebral metastatic melanoma: factors affecting local disease control and survival

1998 • 265 citations

Radiosurgery for brain metastases: Relationship of dose and pattern of enhancement to local control

1997 • 264 citations

Brain metastasis from prostate carcinoma

2003 • 219 citations

Application of recursive partitioning analysis and evaluation of the use of whole brain radiation among patients treated with stereotactic radiosurgery for newly diagnosed brain metastases

2000 • 206 citations

Stereotactic Radiosurgery for Patients with ???Radioresistant??? Brain Metastases

2002 • 201 citations

A cost-effectiveness and cost-utility analysis of radiosurgery vs. resection for single-brain metastases

1997 • 198 citations

Defining the Role of Stereotactic Radiosurgery Versus Microsurgery in the Treatment of Single Brain Metastases

2000 • 198 citations

Prophylactic Cranial Irradiation in Locally Advanced Non–Small-Cell Lung Cancer After Multimodality Treatment: Long-Term Follow-Up and Investigations of Late Neuropsychologic Effects

1999 • 194 citations

Surgical treatment of primary lung cancer with synchronous brain metastases

2001 • 191 citations

Detection of Brain Metastasis in Potentially Operable Non-small Cell Lung Cancer

1999 • 191 citations

The Cost Effectiveness of Stereotactic Radiosurgery versus Surgical Resection in the Treatment of Solitary Metastatic Brain Tumors

1995 • 191 citations

Surgical Management of Non-small Cell Lung Cancer With Synchronous Brain Metastases

2001 • 190 citations

Subacute brain atrophy after radiation therapy for malignant brain tumor

1989 • 185 citations

Preirradiation paclitaxel in glioblastoma multiforme: efficacy, pharmacology, and drug interactions. New Approaches to Brain Tumor Therapy Central Nervous System Consortium.

1997 • 181 citations

Reoperation for recurrent metastatic brain tumors

1995 • 181 citations

Brain Metastases Treated with Radiosurgery Alone: An Alternative to Whole Brain Radiotherapy?

2004 • 178 citations

Surgical treatment of 70 patients with brain metastases from breast carcinoma

1997 • 168 citations

Equivalence of radiation schedules for the palliative treatment of brain metastases in patients with favorable prognosis

1981 • 167 citations

Brain metastases in locally advanced nonsmall cell lung carcinoma after multimodality treatment

2002 • 164 citations

Resection of brain metastases from colorectal carcinoma in 73 patients

1999 • 162 citations

Properly selected patients with multiple brain metastases may benefit from aggressive treatment of their intracranial disease.

2003 • 162 citations

Surgical resection of brain metastases from renal cell carcinoma in 50 patients

1996 • 154 citations

Diagnosis and Management of Central Nervous System Metastases from Breast Cancer

2003 • 153 citations

Craniotomy for the resection of metastatic brain tumors in the U.S., 1988–2000

2004 • 144 citations

Symptom response after palliative radiotherapy for patients with brain metastases

2002 • 136 citations

Brain Metastases in Patients with Ovarian Carcinoma: Prognostic Factors and Outcome

2004 • 130 citations

Metastasis of esophageal carcinoma to the brain

2003 • 129 citations

The treatment of patients with recurrent brain metastases. A retrospective analysis of 109 patients with nonsmall cell lung cancer

1995 • 123 citations

Hypofractionated stereotactic radiotherapy as an alternative to radiosurgery for the treatment of patients with brain metastases

2000 • 121 citations

Gamma Knife Radiosurgery for Malignant Melanoma Brain Metastases

2006 • 118 citations

The role of chemotherapy in brain metastases

2003 • 117 citations

Stereotactic radiosurgery for brainstem metastases

1999 • 113 citations

Cancer of the Nervous System

2004 • 106 citations

Brain metastases as the only manifestation of an undetected primary tumor

1998 • 86 citations

Brain metastases in small cell lung cancer.

2004 • 79 citations

Role of surgical resection for lung, liver, and central nervous system metastases in patients with gynecological cancer: a literature review

2004 • 77 citations

Stereotactic radiosurgery for brain metastases.

1999 • 75 citations

Factors influencing survival after gamma knife radiosurgery for patients with single and multiple brain metastases.

1996 • 67 citations

Gamma knife radiosurgery for simultaneous multiple metastatic brain tumors.

2000 • 64 citations

Investigating the Palliative Efficacy of Whole-brain Radiotherapy for Patients with Multiple-brain Metastases and Poor Prognostic Features

2003 • 62 citations

Gamma knife radiosurgery for metastatic tumours in the brain stem

2003 • 58 citations

Brain metastases in patients with no known primary tumor

2000 • 58 citations

Radiotherapy for brain metastases: defining palliative response

2001 • 53 citations

Radiation Necrosis after Treatment of Solitary Intracranial Metastases

1981 • 50 citations

Brain metastases in patients with cancer of unknown primary.

2003 • 49 citations

Direct costs of microsurgical management of radiosurgically amenable intracranial pathology in Germany: an analysis of meningiomas, acoustic nEuromas, metastases and arteriovenous malformations of less than 3 cm in diameter

2003 • 46 citations

Gamma knife radiosurgery for simultaneous multiple metastatic brain tumors

2000 • 45 citations

The effect of temozolomide-based chemotherapy in patients with cerebral metastases from melanoma

2004 • 45 citations

Of the nervous system.

2010 • 44 citations

Role of radiosurgery in the management of central nervous system metastases

1999 • 39 citations

The origin of brain metastases in patients with an undiagnosed primary tumour

2004 • 38 citations

A single institutional outcome analysis of Gamma Knife radiosurgery for single or multiple brain metastases

2000 • 35 citations

Supportive Care Management of Brain Metastases: What is Known and What We Need to Know

2003 • 28 citations

Prophylactic cranial irradiation in lung cancer

2004 • 21 citations

A Comparison of Craniotomy and Gamma Knife Charges in a Community-Based Gamma Knife Center

1996 • 21 citations

Extremely Delayed Cerebral Metastasis from Renal Carcinoma Report of Four Cases and Critical Analysis of the Literature

2004 • 15 citations