Lower Cognitive Performance in Normal Older Adult Male Twins Carrying the Apolipoprotein E 4 Allele

“Mini-mental state”

1975 • 82,784 citations

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

1993 • 8,888 citations

Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.

1993 • 4,145 citations

Association of apolipoprotein E allele ϵ4 with late‐onset familial and sporadic Alzheimer's disease

1993 • 3,693 citations

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.

1990 • 2,936 citations

Population-Based Norms for the Mini-Mental State Examination by Age and Educational Level

1993 • 2,707 citations

Apolipoprotein E polymorphism and atherosclerosis.

1988 • 2,007 citations

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

1994 • 1,813 citations

Genetic associations with human longevity at the APOE and ACE loci

1994 • 1,079 citations

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage.

1991 • 762 citations

Apolipoprotein E ∈4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases

1993 • 504 citations

Detection and Staging of Dementia in Alzheimer's Disease

1992 • 482 citations

Development of dementing illnesses in an 80‐year‐old volunteer cohort

1989 • 454 citations

Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease

1994 • 449 citations

Detection of dementia in the elderly using telephone screening of cognitive status

1993 • 440 citations

The apolipoprotein ε4 allele in patients with Alzheimer's disease

1993 • 401 citations

Apolipoprotein E polymorphism and coronary artery disease.

1983 • 352 citations

Apolipoprotein E: risk factor for Alzheimer disease.

1994 • 253 citations

Neuropsychologic Detection of Abnormal Mental Decline in Older Persons

1985 • 204 citations

Hereditary Influences on Cognitive Functioning in Older Men

1993 • 128 citations

Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type

1987 • 86 citations

Decline in Cognitive Performance in Aging Twins

1992 • 85 citations

Genetic association and linkage analysis of the apolipoprotein CII locus and familial Alzheimer's disease

1992 • 76 citations

Plasma apolipoproteins in patients with multi-infarct dementia

1989 • 65 citations

Heritability of Cognitive Performance in Aging Twins The National Heart, Lung, and Blood Institute Twin Study

1990 • 58 citations

Concordance of ischemic heart disease in the NHLBI twin study after 14–18 years of follow-up

1991 • 46 citations

Cognitive performance in relatives of patients with probable Alzheimer disease: An age at onset effect?

1992 • 33 citations