Identification of Upregulated Genes in Scrapie-Infected Brain Tissue

Prions

1998 • 5,102 citations

Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

1996 • 3,063 citations

Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

1997 • 1,396 citations

Activation of microglial cells by β-amyloid protein and interferon-γ

1995 • 1,298 citations

Neurotoxicity of a prion protein fragment

1993 • 937 citations

A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

1998 • 810 citations

B Cell–attracting Chemokine 1, a Human CXC Chemokine Expressed in Lymphoid Tissues, Selectively Attracts B Lymphocytes via BLR1/CXCR5

1998 • 807 citations

Mig and IP-10: CXC chemokines that target lymphocytes

1997 • 802 citations

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1997 • 552 citations

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

1996 • 506 citations

Expression of chemokine receptors by subsets of neurons in the central nervous system.

1997 • 384 citations

Microglial Activation Resulting from CD40-CD40L Interaction After β-Amyloid Stimulation

1999 • 356 citations

Strain-dependent Differences in β-Sheet Conformations of Abnormal Prion Protein

1998 • 313 citations

Neuropathological changes in scrapie and Alzheimer's disease are associated with increased expression of apolipoprotein E and cathepsin D in astrocytes

1991 • 297 citations

Isolation of cDNAs of scrapie-modulated RNAs by subtractive hybridization of a cDNA library.

1988 • 286 citations

Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease

1999 • 263 citations

A Study of the Interferon Antiviral Mechanism: Apoptosis Activation by the 2–5A System

1997 • 262 citations

Role of Microglia in Neuronal Cell Death in Prion Disease

1998 • 237 citations

Prion research: the next frontiers

1997 • 221 citations

Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents

1999 • 182 citations

Gene Expression in Scrapie

1998 • 153 citations

Characterization of the microglial response in murine scrapie

1994 • 144 citations

Activation of cerebral cytokine gene expression and its correlation with onset of reactive astrocyte and acute-phase response gene expression in scrapie

1994 • 136 citations

Immunocytochemical appearance of cytokines, prostaglandin E2 and lipocortin-1 in the CNS during the incubation period of murine scrapie correlates with progressive PrP accumulations

1997 • 131 citations

Microglial Activation Varies in Different Models of Creutzfeldt-Jakob Disease

1999 • 89 citations

Cloning of a Gene Whose Expression Is Increased in Scrapie and in Senile Plaques in Human Brain

1985 • 68 citations

Expression of Polyubiquitin and Heat‐Shock Protein 70 Genes Increases in the Later Stages of Disease Progression in Scrapie‐Infected Mouse Brain

1994 • 67 citations

Upregulation of the Genes Encoding Lysosomal Hydrolases, a Perforin-Like Protein, and Peroxidases in the Brains of Mice Affected with an Experimental Prion Disease

2000 • 67 citations

Effect of repeated oral infection of hamsters with scrapie.

1998 • 57 citations

The molecular pathogenesis of astrogliosis in scrapie and Alzheimer's disease

1987 • 55 citations

The Human Spongiform Encephalopathies: Kuru, Creutzfeldt-Jakob Disease, and the Gerstmann-Sträussler-Scheinker Syndrome

1991 • 50 citations

Microglia and prion disease: a review.

1997 • 44 citations

Transcriptional regulation of chemokine gene expression in astrocytes

1996 • 36 citations

Reactive astroglia‐neuron relationships in the human cerebellar cortex: A quantitative, morphological and immunocytochemical study in Creutzfeldt‐Jakob disease

1993 • 35 citations

Human TSE disease — viral or protein only?

1997 • 29 citations

Identification of differentially expressed genes in scrapie-infected mouse neuroblastoma cells

1995 • 25 citations

The Scrapie Fibril Protein and Its Cellular Isoform

1991 • 24 citations

Localization of 2′,5′-oligoadenylate synthetase and the enhancement of its activity with recombinant interferon-α A/D in the mouse brain

1997 • 15 citations