A naturally occurring isoform of the human macrophage scavenger receptor (SR-A) gene generated by alternative splicing blocks modified LDL uptake

A Receptor-Mediated Pathway for Cholesterol Homeostasis

1986 • 5,638 citations

Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition

1979 • 2,458 citations

LIPOPROTEIN METABOLISM IN THE MACROPHAGE: Implications for Cholesterol Deposition in Atherosclerosis

1983 • 2,306 citations

The Biochemistry of Glycoproteins and Proteoglycans

1980 • 1,231 citations

A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection

1997 • 1,210 citations

STRUCTURES AND FUNCTIONS OF MULTILIGAND LIPOPROTEIN RECEPTORS: Macrophage Scavenger Receptors and LDL Receptor-Related Protein (LRP)

1994 • 1,175 citations

Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils

1990 • 1,039 citations

Expression cloning of SR-BI, a CD36-related class B scavenger receptor.

1994 • 818 citations

Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils

1996 • 726 citations

Microglial Cells Internalize Aggregates of the Alzheimer's Disease Amyloid β-Protein Via a Scavenger Receptor

1996 • 649 citations

Cloning of a novel bacteria-binding receptor structurally related to scavenger receptors and expressed in a subset of macrophages

1995 • 501 citations

Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II

1990 • 460 citations

Role for the class A macrophage scavenger receptor in the phagocytosis of apoptotic thymocytes in vitro.

1996 • 427 citations

Human macrophage scavenger receptors: primary structure, expression, and localization in atherosclerotic lesions.

1990 • 360 citations

The SRCR superfamily: a family reminiscent of the Ig superfamily

1994 • 359 citations

Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor

1993 • 348 citations

An ancient, highly conserved family of cysteine-rich protein domains revealed by cloning type I and type II murine macrophage scavenger receptors.

1990 • 311 citations

Purification and characterization of a bovine acetyl low density lipoprotein receptor.

1988 • 259 citations

Structure of Glycoproteins and Their Oligosaccharide Units

1980 • 243 citations

Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster.

1995 • 243 citations

Expression of type I and type II bovine scavenger receptors in Chinese hamster ovary cells: lipid droplet accumulation and nonreciprocal cross competition by acetylated and oxidized low density lipoprotein.

1991 • 214 citations

Murine macrophage scavenger receptor: in vivo expression and function as receptor for macrophage adhesion in lymphoid and non‐lymphoid organs

1995 • 208 citations

Structures and high and low affinity ligand binding properties of murine type I and type II macrophage scavenger receptors

1993 • 155 citations

The collagenous domains of macrophage scavenger receptors and complement component C1q mediate their similar, but not identical, binding specificities for polyanionic ligands.

1993 • 150 citations

Structure, organization, and chromosomal mapping of the human macrophage scavenger receptor gene.

1993 • 132 citations

Differential expression of scavenger receptor isoforms during monocyte-macrophage differentiation and foam cell formation.

1994 • 125 citations

Structures of Class A Macrophage Scavenger Receptors

1996 • 86 citations

The type I and type II bovine scavenger receptors expressed in Chinese hamster ovary cells are trimeric proteins with collagenous triple helical domains comprising noncovalently associated monomers and Cys83-disulfide-linked dimers.

1991 • 63 citations

Structure and chromosomal location of the human CD6 gene: detection of five human CD6 isoforms.

1997 • 54 citations

Enhanced scavenger receptor expression in monocyte-macrophages in dialysis patients

1996 • 47 citations

Functional and possible physical association of scavenger receptor with cytoplasmic tyrosine kinase Lyn in monocytic THP‐1‐derived macrophages

1996 • 45 citations

A novel multi-gene family of sheep gamma delta T cells.

1994 • 43 citations

Dominant negative mutations of the scavenger receptor. Native receptor inactivation by expression of truncated variants.

1993 • 37 citations

Characterization of inherited scavenger receptor overexpression and abnormal macrophage phenotype in a normolipidemic subject with planar xanthomas.

1996 • 26 citations

Differential regulation of macrophage scavenger receptor isoforms: mRNA quantification using the polymerase chain reaction

1995 • 25 citations

Lipoprotein regulation of cholesterol metabolism in macrophages derived from human monocytes.

1982 • 23 citations

Lymph node homing cells biologically enriched for γδ T cells express multiple genes from the T19 repertoire

1994 • 19 citations