Increased Aryl Hydrocarbon Hydroxylase Activity in Hepatic Microsomes from Streptozotocin-Diabetic Female Rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.

1976 • 483 citations

Sex-Related Differences in Drug Metabolism

1975 • 408 citations

Aryl hydrocarbon (benzo[a]pyrene) hydroxylase in microsomes from rat tissues: Differential inhibition and stimulation by benzoflavones and organic solvents

1971 • 374 citations

Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene

1967 • 334 citations

Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.

1976 • 316 citations

A modified method for the assay of benzo[a]pyrene hydroxylase

1973 • 295 citations

Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.

1965 • 259 citations

The use of nicotinamide to modify the toxicity of streptozotocin diabetes without loss of antitumor activity.

1967 • 194 citations

Alpha-Naphthoflavone: An Inhibitor of Hydrocarbon Cytotoxicity and Microsomal Hydroxylase

1969 • 185 citations

Streptozotocin: depression of mouse liver pyridine nucleotides.

1968 • 136 citations

The metabolism of drugs by liver microsomes from alloxan-diabetic rats.

1961 • 116 citations

Effects of Streptozotocin on Carbohydrate and Lipid Metabolism in the Rat

1971 • 94 citations

Streptozotocin diabetes—further studies on the mechanism of depression of nicotinamide adenine dinucleotide concentrations in mouse pancreatic islets and liver

1973 • 92 citations

DIFFERENCES AMONG THE ACTION OF PHENOBARBITAL, METHYLCHOLANTHRENE AND MALE SEX HORMONE ON MICROSOMAL DRUG-METABOLIZING ENZYME SYSTEMS OF RAT LIVER

1966 • 88 citations

Studies on the Ability of Compounds to Block the Diabetogenic Activity of Streptozotocin

1969 • 74 citations

Altered Activity of Hepatic Mixed-Function Monooxygenase Enzymes in Streptozotocin-induced Diabetic Rats

1978 • 68 citations

THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.

1963 • 61 citations

Streptozotocin: Its excretion and metabolism in the rat

1976 • 61 citations

Properties of benzpyrene hydroxylase in the liver, intestinal mucosa and adrenal of untreated and 3-methylcholanthrene-treated rats.

1973 • 58 citations

Effect of experimental diabetes on drug metabolism in the rat.

1977 • 51 citations

Xenobiotic metabolism and enzyme induction in isolated rat intestinal microsomes.

1976 • 50 citations

A comprehensive study of in vitro drug metabolism in several laboratory species.

1976 • 48 citations

THE ROLE OF CYTOCHROME P‐450 AND P‐448 IN DRUG AND STEROID HYDROXYLATIONS

1973 • 41 citations

SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (I) THE ACTIVITY OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM

1970 • 38 citations

Plasma Glucose Levels in Normal and Adrenalectomized Mice Treated with Streptozotocin and Nicotinamide

1968 • 37 citations

Metabolism of Normal Body Constituents by Drug-Metabolizing Enzymes in Liver Microsomes

1971 • 36 citations

Metyrapone and other modifiers of microsomal drug metabolism.

1973 • 33 citations

Metabolism in vitro of digitoxigenin by rat liver homogenates

1971 • 31 citations

DIFFERENCES IN THE OXIDATIVE METABOLISM OF DRUGS BY LIVER MICROSOMES

1969 • 23 citations

Sex-dependent regulation of benzo[a]pyrene and zoxazolamine metabolism in rat tissues.

1977 • 20 citations

SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (II) THE SUBSTRATE INTERACTION WITH CYTOCHROME P-450 IN DRUG OXIDATION

1970 • 13 citations

SPECIES AND SEX DIFFERENCES IN AMINOPYRINE N-DEMETHY-LATING ACTIVITY OF LIVER MICROSOMES UNDER UNPHYSIOLOGICAL CONDITIONS

1968 • 9 citations

Effects of inhibitors on drug metabolism.

1973 • 8 citations

EFFECT OF PHENOBARBITAL ON THE ACTIVITIES OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM OF LIVER MICROSOMES IN ALLOXAN DIABETES AND THYROXINE TREATED RATS

1969 • 6 citations

Early effects of the administration of streptozotocin on muscle glycogen

1976 • 1 citations