Back to search

Altered Activity of Hepatic Mixed-Function Monooxygenase Enzymes in Streptozotocin-induced Diabetic Rats

Data up to Jan 2025

Published1978
Citations68
References30

Total Citations Per Year

Abstract

References (30)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Carbon Monoxide-binding Pigment of Liver Microsomes

1964 • 11,832 citations

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

1976 • 972 citations

Studies on the diabetogenic action of streptozotocin

1963 • 831 citations

EFFECT OF STARVATION ON NADPH-DEPENDENT ENZYMES IN LIVER MICROSOMES OF MALE AND FEMALE RATS

1965 • 542 citations

Sex-Related Differences in Drug Metabolism

1975 • 408 citations

Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.

1965 • 259 citations

Light and Electron Microscopy of Lesions in Rats Rendered Diabetic with Streptozotocin

1967 • 247 citations

Inherent specificities of purified cytochromes P-450 and P-448 toward biphenyl hydroxylation and ethoxyresorufin deethylation.

1975 • 209 citations

Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.

1975 • 150 citations

The metabolism of drugs by liver microsomes from alloxan-diabetic rats.

1961 • 116 citations

The stimulation of hydroxylation by carcinogenic and non-carcinogenic compounds

1966 • 92 citations

Comparison of streptozotocin and alloxan-induced diabetes in the rat, including volumetric quantitation of the pancreatic islets

1973 • 82 citations

THE RELATIONSHIP BETWEEN THE MECHANISM OF ACTION OF THE SULFONYLUREAS AND THE SECRETION OF INSULIN INTO THE PORTAL CIRCULATION

1959 • 69 citations

THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.

1963 • 61 citations

Effect of enzyme inducers on substrate specificity of the cytochrome P-450's.

1973 • 56 citations

The Metabolism of Biphenyl. II. Phenolic Metabolites in the Rat

1976 • 51 citations

Effect of experimental diabetes on drug metabolism in the rat.

1977 • 51 citations

A comprehensive study of in vitro drug metabolism in several laboratory species.

1976 • 48 citations

SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (I) THE ACTIVITY OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM

1970 • 38 citations

Biphenyl Hydroxylations and Spectrally Apparent Interactions with Liver Microsomes from Hamsters Pre-treated with Phenobarbitone and 3-Methylcholanthrene

1975 • 37 citations

Metabolism in vitro of digitoxigenin by rat liver homogenates

1971 • 31 citations

Effect of adrenalectomy or alloxan diabetes on the substrate interaction with cytochrome p-450 in the oxidation of drugs by liver microsomes

1971 • 26 citations

The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes

1976 • 24 citations

SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (II) THE SUBSTRATE INTERACTION WITH CYTOCHROME P-450 IN DRUG OXIDATION

1970 • 13 citations

Alkyl streptozotocin analogues with improved biological activities

1976 • 12 citations

SPECIES AND SEX DIFFERENCES IN AMINOPYRINE N-DEMETHY-LATING ACTIVITY OF LIVER MICROSOMES UNDER UNPHYSIOLOGICAL CONDITIONS

1968 • 9 citations

The metabolic transformation of phenylbutazone in the alloxan diabetic rat

1974 • 9 citations

Prolongation of Hypnosis by Epinephrine and Insulin

1945 • 6 citations

EFFECT OF PHENOBARBITAL ON THE ACTIVITIES OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM OF LIVER MICROSOMES IN ALLOXAN DIABETES AND THYROXINE TREATED RATS

1969 • 6 citations

Cited By (0)

Loading...
Altered Activity of Hepatic Mixed-Function Monooxygenase Enzymes in… (1978) – Xenobiotica | Metascience Observatory Explorer