Altered Activity of Hepatic Mixed-Function Monooxygenase Enzymes in Streptozotocin-induced Diabetic Rats
Data up to Jan 2025
Total Citations Per Year
Abstract
References (30)
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
1951 • 319,299 citations
The Carbon Monoxide-binding Pigment of Liver Microsomes
1964 • 11,832 citations
Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus
1976 • 972 citations
Studies on the diabetogenic action of streptozotocin
1963 • 831 citations
EFFECT OF STARVATION ON NADPH-DEPENDENT ENZYMES IN LIVER MICROSOMES OF MALE AND FEMALE RATS
1965 • 542 citations
Sex-Related Differences in Drug Metabolism
1975 • 408 citations
Sex differences in the effects of abnormal physiological states on the metabolism of drugs by rat liver microsomes.
1965 • 259 citations
Light and Electron Microscopy of Lesions in Rats Rendered Diabetic with Streptozotocin
1967 • 247 citations
Inherent specificities of purified cytochromes P-450 and P-448 toward biphenyl hydroxylation and ethoxyresorufin deethylation.
1975 • 209 citations
Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.
1975 • 150 citations
The metabolism of drugs by liver microsomes from alloxan-diabetic rats.
1961 • 116 citations
The stimulation of hydroxylation by carcinogenic and non-carcinogenic compounds
1966 • 92 citations
Comparison of streptozotocin and alloxan-induced diabetes in the rat, including volumetric quantitation of the pancreatic islets
1973 • 82 citations
THE RELATIONSHIP BETWEEN THE MECHANISM OF ACTION OF THE SULFONYLUREAS AND THE SECRETION OF INSULIN INTO THE PORTAL CIRCULATION
1959 • 69 citations
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.
1963 • 61 citations
Effect of enzyme inducers on substrate specificity of the cytochrome P-450's.
1973 • 56 citations
The Metabolism of Biphenyl. II. Phenolic Metabolites in the Rat
1976 • 51 citations
Effect of experimental diabetes on drug metabolism in the rat.
1977 • 51 citations
A comprehensive study of in vitro drug metabolism in several laboratory species.
1976 • 48 citations
SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (I) THE ACTIVITY OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM
1970 • 38 citations
Biphenyl Hydroxylations and Spectrally Apparent Interactions with Liver Microsomes from Hamsters Pre-treated with Phenobarbitone and 3-Methylcholanthrene
1975 • 37 citations
Metabolism in vitro of digitoxigenin by rat liver homogenates
1971 • 31 citations
Effect of adrenalectomy or alloxan diabetes on the substrate interaction with cytochrome p-450 in the oxidation of drugs by liver microsomes
1971 • 26 citations
The effects of benzopyrene and safrole on biphenyl 2-hydroxylase and other drug-metabolizing enzymes
1976 • 24 citations
SPECIES DIFFERENCE IN DRUG METABOLISM BY LIVER MICROSOMES IN ALLOXAN DIABETIC OR FASTED ANIMALS (II) THE SUBSTRATE INTERACTION WITH CYTOCHROME P-450 IN DRUG OXIDATION
1970 • 13 citations
Alkyl streptozotocin analogues with improved biological activities
1976 • 12 citations
SPECIES AND SEX DIFFERENCES IN AMINOPYRINE N-DEMETHY-LATING ACTIVITY OF LIVER MICROSOMES UNDER UNPHYSIOLOGICAL CONDITIONS
1968 • 9 citations
The metabolic transformation of phenylbutazone in the alloxan diabetic rat
1974 • 9 citations
Prolongation of Hypnosis by Epinephrine and Insulin
1945 • 6 citations
EFFECT OF PHENOBARBITAL ON THE ACTIVITIES OF DRUG-METABOLIZING ENZYMES AND ELECTRON TRANSPORT SYSTEM OF LIVER MICROSOMES IN ALLOXAN DIABETES AND THYROXINE TREATED RATS
1969 • 6 citations